Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marcos G. Ocaña"'
Autor:
Laura Pérez-Is, Marcos G Ocaña, A Hugo Montes, José A Carton, Victoria Álvarez, Álvaro Meana, Joshua Fierer, Eulalia Valle-Garay, Víctor Asensi
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0220022 (2019)
BACKGROUND:Osteomyelitis is a bone infection, most often caused by Staphylococcus aureus, in which neutrophils play a key role. Cathepsin G (CTSG) is a bactericidal serine protease stored in the neutrophil azurophilic granules. CTSG regulates inflamm
Externí odkaz:
https://doaj.org/article/d7c2e44518554947a0a80d88bb899b8a
Autor:
Marcos G. Ocaña, Victoria Alvarez, José A. Carton, Eulalia Valle-Garay, Alvaro Meana, Laura Pérez-Is, Joshua Fierer, Victor Asensi, A Hugo Montes
Publikováno v:
PloS one, vol 14, iss 10
PLoS ONE, Vol 14, Iss 10, p e0220022 (2019)
PLoS ONE
PLoS ONE, Vol 14, Iss 10, p e0220022 (2019)
PLoS ONE
Author(s): Perez-Is, Laura; Ocana, Marcos G; Montes, A Hugo; Carton, Jose A; Alvarez, Victoria; Meana, Alvaro; Fierer, Joshua; Valle-Garay, Eulalia; Asensi, Victor | Abstract: BACKGROUND:Osteomyelitis is a bone infection, most often caused by Staphyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35895b0a9c8cc8462b00b0d75015078
https://escholarship.org/uc/item/20c4q1hb
https://escholarship.org/uc/item/20c4q1hb
Autor:
Marcos G. Ocaña, A. H. Montes, Antonio Celada, Alvaro Meana, Victor Asensi, Eulalia Valle-Garay
Publikováno v:
Molecular Immunology. 45:2087-2096
Neutrophils (PMN), potent phagocytes, are the first line of the host immune defence against microorganisms, especially bacteria. Their half-life is very short and they are eliminated through apoptosis. Delayed neutrophil apoptosis is a characteristic
Autor:
Marcos G. Ocaña, Victor Asensi, Pelayo González, Antonio Celada, Angeles Solís, Eulalia Valle, Alvaro Meana, A Hugo Montes, José C. Paz, José A. Carton, Esteban López-Anglada, Joshua Fierer, Victoria Alvarez, Eliecer Coto, Aurora Astudillo
Publikováno v:
Nitric Oxide. 16:44-53
Cytokines generate nitric oxide (NO) in osteoblasts and neutrophils through the induction of NO synthase isoforms, endothelial (NOS3) and inducible (NOS2), thereby producing bone loss. In osteomyelitis (OM), a chronic infection of the bone, homozygos
Autor:
Marcos G. Ocaña, Alvaro Meana, J. A. Cartón, José C. Paz, Eulalia Valle, A. H. Montes, Victoria Alvarez, Joshua Fierer, Antonio Celada, Victor Asensi
Publikováno v:
Clinical and Experimental Immunology. 143:404-413
Summary Osteomyelitis is a bone infection caused mostly by Staphylococcus aureus but also by Gram-negative bacteria. Toll-like receptors (TLRs), after recognizing microbial products, induce a signal in neutrophils, leading to NF-κB activation and tr
Autor:
Marcos G. Ocaña, José A. Carton, Victor Asensi, A Hugo Montes, Joshua Fierer, Alvaro Meana, Eulalia Valle-Garay, Antonio Celada
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics. 9(4)
Background: Patients with osteomyelitis have a decreased rate of spontaneous apoptosis of their peripheral blood neutrophils. The G(-248)A polymorphism in the promoter region of the bax gene is associated with prolonged peripheral blood neutrophil su