Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marcos Francia"'
Autor:
Ariel Waisman, Federico Sevlever, Denisse Saulnier, Marcos Francia, Renata Blanco, Guadalupe Amín, Antonella Lombardi, Celeste Biani, María Belén Palma, Agustina Scarafía, Joaquín Smucler, Alejandro La Greca, Lucía Moro, Gustavo Sevlever, Alejandra Guberman, Santiago Miriuka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract In the mouse embryo, the transition from the preimplantation to the postimplantation epiblast is governed by changes in the gene regulatory network (GRN) that lead to transcriptional, epigenetic, and functional changes. This transition can b
Externí odkaz:
https://doaj.org/article/1a80d6d925074305b31faed269cd36f7
Autor:
Juan José Romero, María Cecilia De Rossi, Camila Oses, Camila Vázquez Echegaray, Paula Verneri, Marcos Francia, Alejandra Guberman, Valeria Levi
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background The cytoskeleton is a key component of the system responsible for transmitting mechanical cues from the cellular environment to the nucleus, where they trigger downstream responses. This communication is particularly relevant in e
Externí odkaz:
https://doaj.org/article/2f92720cb1d04535aec50846b16f11ee
Autor:
Claudia Solari, María Victoria Petrone, Ayelén Toro, Camila Vazquez Echegaray, María Soledad Cosentino, Ariel Waisman, Marcos Francia, Lino Barañao, Santiago Miriuka, Alejandra Guberman
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Abstract Objective Redox homeostasis maintenance is essential to bring about cellular functions. Particularly, embryonic stem cells (ESCs) have high fidelity mechanisms for DNA repair, high activity of different antioxidant enzymes and low levels of
Externí odkaz:
https://doaj.org/article/02d83a061a4f40b5ae4b1356fe889a90
Autor:
Marcos Francia, Martin Stortz, Camila Vazquez Echegaray, Camila Oses, Paula Verneri, María Victoria Petrone, Ayelen Toro, Ariel Waisman, Santiago Miriuka, María Soledad Cosentino, Valeria Levi, Alejandra Guberman
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254447 (2021)
Akt/PKB is a kinase involved in the regulation of a wide variety of cell processes. Its activity is modulated by diverse post-translational modifications (PTMs). Particularly, conjugation of the small ubiquitin-related modifier (SUMO) to this kinase
Externí odkaz:
https://doaj.org/article/a6d2bf6311314e98ae454f2f6fa37dd9
Autor:
Ayelén Toro, Nicolás Anselmino, Claudia Solari, Marcos Francia, Camila Oses, Pablo Sanchis, Juan Bizzotto, Camila Vazquez Echegaray, María Victoria Petrone, Valeria Levi, Elba Vazquez, Alejandra Guberman
Publikováno v:
Cells, Vol 10, Iss 1, p 35 (2020)
Stem cells genome safeguarding requires strict oxidative stress control. Heme oxygenase-1 (HO-1) and p53 are relevant components of the cellular defense system. p53 controls cellular response to multiple types of harmful stimulus, including oxidative
Externí odkaz:
https://doaj.org/article/bc89a76d3bd5427b9832539e520bb237
Autor:
Claudia Solari, Camila Vázquez Echegaray, María Soledad Cosentino, María Victoria Petrone, Ariel Waisman, Carlos Luzzani, Marcos Francia, Emilly Villodre, Guido Lenz, Santiago Miriuka, Lino Barañao, Alejandra Guberman
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144336 (2015)
Pluripotent stem cells possess complex systems that protect them from oxidative stress and ensure genomic stability, vital for their role in development. Even though it has been reported that antioxidant activity diminishes along stem cell differenti
Externí odkaz:
https://doaj.org/article/cd449a7449f840cd9e70377be22c7970
Autor:
Alejandra Guberman, Camila Vazquez Echegaray, María Soledad Cosentino, Ayelén Toro, Marcos Francia, Elba Vazquez, Claudia Solari, María Victoria Petrone
Publikováno v:
FEBS Letters. 595:1949-1961
In embryonic stem (ES) cells, oxidative stress control is crucial for genomic stability, self-renewal and cell differentiation. Heme oxygenase-1 (HO-1) is a key player of the anti-oxidant system, and is also involved in stem cell differentiation and
Autor:
Santiago Gabriel Miriuka, Camila Vazquez Echegaray, Lino Barañao, Ariel Waisman, Marcos Francia, Ayelén Toro, María Soledad Cosentino, María Victoria Petrone, Claudia Solari, Alejandra Guberman
Publikováno v:
BMC Research Notes
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Objective: Redox homeostasis maintenance is essential to bring about cellular functions. Particularly, embryonic stem cells (ESCs) have high fidelity mechanisms for DNA repair, high activity of different antioxidant enzymes and low levels of oxidativ
Autor:
Marcos Francia, Santiago Gabriel Miriuka, Gustavo Sevlever, Camila Vazquez Echegaray, Ariel Waisman, María Soledad Cosentino, Marcelo Schultz, Alejandra Guberman, Claudia Solari, Valeria Levi, María Victoria Petrone, Yanina D. Álvarez, Camila Oses
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Chromatin remodeling is fundamental for the dynamical changes in transcriptional programs that occur during development and stem cell differentiation. The histone acetyltransferase Kat6b is relevant for neurogenesis in mouse embryos, and mutations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7022304508af61ab8698c59f49e057fa
https://linkinghub.elsevier.com/retrieve/pii/S0022283619300889
https://linkinghub.elsevier.com/retrieve/pii/S0022283619300889
Autor:
María Soledad Cosentino, Camila Vazquez Echegaray, Marcos Francia, Alejandra Guberman, Lino Barañao, Ariel Waisman, Santiago Gabriel Miriuka, Claudia Solari, María Victoria Petrone
Redox homeostasis is vital for cellular functions and to prevent the detrimental consequences of oxidative stress. Pluripotent stem cells (PSCs) have an enhanced antioxidant system which supports the preservation of their genome. Besides, reactive ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d057415111bb4be2b211110db1dfafe3
https://www.sciencedirect.com/science/article/pii/S0925477318300558
https://www.sciencedirect.com/science/article/pii/S0925477318300558