Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marcos, Jorge R Guimarães"'
Autor:
Matheus de Freitas Silva, Ellen Tardelli Lima, Letizia Pruccoli, Newton G. Castro, Marcos Jorge R. Guimarães, Fernanda M. R. da Silva, Nathalia Fonseca Nadur, Luciana Luiz de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Vanessa Silva Gontijo, Andrea Tarozzi, Claudio Viegas
Publikováno v:
Molecules, Vol 25, Iss 14, p 3165 (2020)
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder that involves different pathogenic mechanisms. In this regard, the goal of this study was the design and synthesis of new compounds with multifunctional pharmacological activit
Externí odkaz:
https://doaj.org/article/766736aee49e4dc6b5abdcf74046e349
Autor:
Sarah, Macedo Vaz, Matheus, de Freitas Silva, Graziella, Dos Reis Rosa Franco, Marcos, Jorge R Guimarães, Fernanda, Motta R da Silva, Newton, Gonçalves Castro, Isabella, Alvim Guedes, Laurent E, Dardenne, Marina, Amaral Alves, Rafael, Garrett da Costa, Gabriela, Beserra Pinheiro, Letícia, Germino Veras, Márcia, Renata Mortari, Letizia, Pruccoli, Andrea, Tarozzi, Cláudio, Viegas
Publikováno v:
Bioorganic & Medicinal Chemistry. 71:116952
The search for new drug candidates against Alzheimer's disease (AD) remains a complex challenge for medicinal chemists due to its multifactorial pathogenesis and incompletely understood physiopathology. In this context, we have explored the molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2eaeeb2b517979d2d8639b8c37f216c
https://doi.org/10.1016/j.bmc.2022.116952
https://doi.org/10.1016/j.bmc.2022.116952
Autor:
Nathalia Fonseca Nadur, Ellen Tardelli Lima, Fernanda Rabaioli da Silva, Matheus de Freitas Silva, Marcos Jorge R. Guimarães, Claudio Viegas, Isabella A. Guedes, Vanessa Silva Gontijo, Andrea Tarozzi, Newton G. Castro, Arthur Eugen Kümmerle, Letizia Pruccoli, Luciana Luiz de Azevedo, Laurent E. Dardenne
Publikováno v:
Molecules
Volume 25
Issue 14
Molecules, Vol 25, Iss 3165, p 3165 (2020)
Volume 25
Issue 14
Molecules, Vol 25, Iss 3165, p 3165 (2020)
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder that involves different pathogenic mechanisms. In this regard, the goal of this study was the design and synthesis of new compounds with multifunctional pharmacological activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323f458908fd9f607d4807dcf8c9c4f3
Autor:
Newton G. Castro, Cynthia T. de Paula, Ivo S.F. Melo, Isis N. O. Souza, Kris Simone Tranches Dias, Gilda Neves, Thiago dos Santos, Letizia Pruccoli, Márcio M. Coelho, Alexandre Giusti-Paiva, Clarice de Carvalho Veloso, Claudio Viegas, Marina da Silva Boni, Fabiana Morroni, Andrea Tarozzi, Isabella A. Guedes, Fernanda Rabaioli da Silva, Marcos Jorge R. Guimarães, Marcelo Lourenço da Silva, Fabiana Cardosos Vilela Giusti, Laurent E. Dardenne
A novel series of feruloyl-donepezil hybrid compounds were designed, synthesized and evaluated as multitarget drug candidates for the treatment of Alzheimer's Disease (AD). InÂvitro results revealed potent acetylcholinesterase (AChE) inhibitory acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2365616dc4ecfb7ed325661055b31834
http://hdl.handle.net/11585/623951
http://hdl.handle.net/11585/623951
Autor:
Jan Korábečný, Marcos Jorge R. Guimarães, Andressa Souza de Oliveira, Fernanda Rabaioli da Silva, Patrícia Coelho do Nascimento Nogueira, Ondřej Soukup, Gina de Castro Couto, Maria Laura Bolognesi, Laís Flávia Nunes Lemes, Manuela Bartolini, Marina da Silva Boni, Newton G. Castro, Edilberto R. Silveira, Isis N. O. Souza, Luiz Antonio Soares Romeiro, Giselle de Andrade Ramos, Guilherme D. Brand, Vincenza Andrisano, Nelilma C. Romeiro
Cardanol is a phenolic lipid component of cashew nut shell liquid (CNSL), obtained as the byproduct of cashew nut food processing. Being a waste product, it has attracted much attention as a precursor for the production of high-value chemicals, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba63b666e902181419989cd712fd62f5
http://hdl.handle.net/11585/588069
http://hdl.handle.net/11585/588069