Neuromuscular and cardiac adverse events associated with immune checkpoint inhibitors: pooled analysis of individual cases from multiple institutions and literature

Autor: Boutros, A., Bottini, A., Rossi, G., Tanda, E.T., Spagnolo, F., Barletta, G., Croce, E., Fava, P., Parisi, A., De Rosa, F., Palla, M., Marconcini, R., Ferrari, M., Grandis, M., Spallarossa, P., Sarocchi, M., Arboscello, E., Del Mastro, L., Lambertini, M., Pronzato, P., Genova, C.

Publikováno v: In ESMO Open February 2023 8(1)

A randomized phase II trial of Captem or Folfiri as second-line therapy in neuroendocrine carcinomas.

Autor: Bongiovanni A; Osteoncology and Rare Tumor Center (CDO-TR), IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Liverani C; Bioscience Laboratory, Preclinic and Osteoncology Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy. Electronic address: chiara.liverani@irst.emr.it., Foca F; Unit of Biostatistics and Clinical Trials, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Bergamo F; Medical Oncology Unit 1, IOV-Veneto Institute of Oncology IRCCS, Padua, Italy., Leo S; Department of Medical Oncology, 'Vito Fazzi' Hospital, Lecce, Italy., Pusceddu S; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, ENETS Center of Excellence, Milan, Italy., Gelsomino F; Department of Oncology and Hematology, Division of Oncology, University Hospital of Modena, Modena, Italy., Brizzi MP; Department of Oncology, 'San Luigi Gonzaga' University Hospital, University of Turin, Orbassano, Italy., Di Meglio G; Medical Oncology Unit, Bolzano Hospital, Bolzano, Italy., Spada F; Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology (IEO) IRCCS, Milan, Italy., Tamberi S; Medical Oncology Unit, 'Degli Infermi' Hospital, Faenza, Italy., Lolli I; Medical Oncology Unit, National Institute of Gastroenterology, IRCCS 'Saverio De Bellis', Castellana Grotte, Italy., Cives M; Department of Interdisciplinary Medicine, 'Aldo Moro' University of Bari, Bari, Italy; Division of Medical Oncology, Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari, Bari, Italy., Marconcini R; Medical Oncology Unit, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy., Pucci F; Medical Oncology Unit, University Hospital of Parma, Parma, Italy., Berardi R; Department of Medical Oncology, Università Politecnica delle Marche, Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona, Ancona, Italy., Antonuzzo L; Clinical Oncology Unit, Careggi University Hospital, Florence, Italy; Department of Experimental and Clinical Medicine, University of Florence, Italy., Badalamenti G; Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, Palermo, Italy., Santini D; Department of Medical Oncology, University Campus Bio-Medico, Rome, Italy., Recine F; Medical Oncology Unit, Azienda Ospedaliera 'San Giovanni Addolorata', Rome, Italy., Vanni S; Bioscience Laboratory, Preclinic and Osteoncology Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Tebaldi M; Unit of Biostatistics and Clinical Trials, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Severi S; Nuclear Medicine and Radiometabolic Units, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Rudnas B; Unit of Biostatistics and Clinical Trials, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Nanni O; Unit of Biostatistics and Clinical Trials, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Ranallo N; Osteoncology and Rare Tumor Center (CDO-TR), IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Crudi L; Department of Oncology, University Hospital of Ferrara, Cona, Italy., Calabrò L; Oncology Pharmacy Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori 'Dino Amadori', 47014 Meldola, Italy; Department of Translational Medicine, University of Ferrara, Ferrara, Italy., Ibrahim T; Osteoncology and Rare Tumor Center (CDO-TR), IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy; Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

Publikováno v: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2024 Sep; Vol. 208, pp. 114129. Date of Electronic Publication: 2024 May 25.

Epidemiology of gastroenteropancreatic neuroendocrine neoplasms: a review and protocol presentation for bridging tumor registry data with the Italian association for neuroendocrine tumors (Itanet) national database.

Autor: Panzuto F; Department of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Digestive Disease Unit, ENETS Center of Excellence, Sant'Andrea University Hospital, Rome, Italy. francesco.panzuto@uniroma1.it., Partelli S; Pancreatic Surgery Unit, Pancreas Translational and Clinical Research Center, ENETS Center of Excellence, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy., Campana D; Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - University of Bologna, Medical Oncology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., de Braud F; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, ENETS Center of Excellence, Milan, Italy., Spada F; Gastrointestinal and Neuroendocrine Tumors Oncology Unit - ENETS Center of Excellence, European Institute of Oncology (IEO) - IRCCS, Milan, Italy., Cives M; Dipartimento Interdisciplinare di Medicina, Università di Bari 'Aldo Moro', Bari, Italy., Tafuto S; S.C. Sarcomi e Tumori Rari, Istituto Nazionale Tumori, I.R.C.C.S. - Fondazione 'G. Pascale', ENETS Center of Excellence, Napoli, Italy., Bertuzzi A; Sezione Sarcomi/NET e Oncologia del Giovane Adulto (AYA-Adolescent Young Adult) Humanitas Research Hospital-IRCCS Via Manzoni 56, 20089, Rozzano, Milan, Italy., Gelsomino F; Department of Oncology and Hematology, Division of Oncology, University Hospital of Modena, Modena, Italy., Bergamo F; Oncology 1, Veneto Institute of Oncology - IRCCS, Padua, Italy., Marcucci S; Department of Surgery & Hepato-Biliary and Pancreatic Unit Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), Trento, Italy., Mastrangelo L; UO Chirurgia Generale e d'Urgenza IRCCS Azienda Ospedaliera Universitaria Sant'Orsola Malpighi c/o Ospedale Maggiore, Bologna, Italy., Massironi S; Division of Gastroenterology, Fondazione IRCCS San Gerardo dei Tintori, and University of Milano-Bicocca, School of Medicine, Monza, Italy., Appetecchia M; Oncological Endocrinology Unit, Regina Elena National Cancer Institutre - IFO IRCCS, Roma, Italy., Filice A; Servizio di Medicina Nucleare, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Badalamenti G; Department of Surgical, Oncological and Oral Sciences, University of Palermo, Palermo, Italy., Bartolomei M; Nuclear Medicine Unit, Azienda Ospedaliera Universitaria-Ferrara, Ferrara, Italy., Amoroso V; Medical Oncology Unit, Department of Medical & Surgical Specialties, Radiological Sciences & Public Health, University of Brescia at Spedali Civili Hospital, Brescia, Italy., Landoni L; Department of General and Pancreatic Surgery, The Pancreas Institute, University of Verona Hospital Trust, ENETS Center of Excellence, Verona, Italy., Rodriquenz MG; Oncology Unit - Ospedale IRCCS Casa Sollievo della Sofferenza - San Giovanni Rotondo, Foggia, Italy., Valente M; Center for Immuno-Oncology, Oncology Department, University Hospital of Siena, Siena, Italy., Colao A; Department of Endocrinology University of Naples, Azienda Ospedaliera Universitaria 'Federico II', ENETS CEnter of Excellence, Napoli, Italy., Isidori A; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy., Fanciulli G; Endocrine Oncology Program, Endocrine Unit, University Hospital (AOU) of Sassari, Sassari, Italy., Bollina R; Presidio Ospedaliero di Rho, Milan, Italy., Ciola M; Regional Hospital of Bolzano, Bolzano, Italy., Butturini G; HPB Surgery, P. Pederzoli Hospital, Peschiera del Garda, Verona, Italy., Marconcini R; Medical Oncology Unit, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy., Arvat E; Oncological Endocrinology Unit, Department of Medical Sciences University of Turin, Turin, Italy., Cinieri S; Oncology Unit, A. Perrino Hospital, Brindisi, Italy., Berardi R; Department of Medical Oncology, Università Politecnica Delle Marche, AOU Ospedali Riuniti Delle Marche, Ancona, Italy., Baldari S; Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Messina, Italy., Riccardi F; Medical Oncology Unit, Ospedale Cardarelli, Naples, Italy., Spoto C; Medical Oncology, Santa Maria Goretti Hospital, Latina, Italy., Giuffrida D; Medical Oncology Department, Istituto Oncologico del Mediterraneo, Viagrande, Catania, Italy., Gattuso D; Oncology Unit, S. Filippo Neri Hospital ASL Roma 1, Rome, Italy., Ferone D; Endocrinology Unit, Department of Internal Medicine & Medical Specialties (DiMI), IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy., Rinzivillo M; Department of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Digestive Disease Unit, ENETS Center of Excellence, Sant'Andrea University Hospital, Rome, Italy., Bertani E; Digestive Surgery, European Institute of Oncology IRCCS, ENETS Center of Excellence, Milan, Italy., Versari A; Servizio di Medicina Nucleare, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Zerbi A; Humanitas Research Hospital -IRCCS, Pancreatic Surgery Unit, Rozzano, and Humanitas University, Department of Biomedical Sciences, Pieve Emanuele, Italy., Lamberti G; Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - University of Bologna, Medical Oncology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Lauricella E; Dipartimento Interdisciplinare di Medicina, Università di Bari 'Aldo Moro', Bari, Italy., Pusceddu S; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, ENETS Center of Excellence, Milan, Italy., Fazio N; Gastrointestinal and Neuroendocrine Tumors Oncology Unit - ENETS Center of Excellence, European Institute of Oncology (IEO) - IRCCS, Milan, Italy., Dell'Unto E; Department of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Digestive Disease Unit, ENETS Center of Excellence, Sant'Andrea University Hospital, Rome, Italy., Marini M; IMT School for Advanced Studies Lucca, Lucca, Italy., Falconi M; Pancreatic Surgery Unit, Pancreas Translational and Clinical Research Center, ENETS Center of Excellence, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy.

Publikováno v: Endocrine [Endocrine] 2024 Apr; Vol. 84 (1), pp. 42-47. Date of Electronic Publication: 2024 Jan 04.

TGF-β mRNA Expression Levels in Extracellular Vesicles Are Associated With Immunotherapy Response in Metastatic Melanoma Patients

Autor: Crucitta, S., Cucchiara, F., Marconcini, R., Bulleri, A., Manacorda, S., Cioni, D., Nuzzo, A., De Jonge, E., Mathjissen, R., Neri, E., van Schaik, R., Fogli, S., Danesi, R., Del Re, M.

Publikováno v: In The Journal of Liquid Biopsy November 2023 1 Supplement

Outcomes in patients with BRAF ^V600 -mutated melanoma and brain metastases at baseline treated with dabrafenib plus trametinib.

Autor: Aglietta M; Department of Oncology, University of Torino, Torino, Italy.; Department of Medical Oncology, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Chiarion-Sileni V; Melanoma Unit, Veneto Institute of Oncology IOV-IRCCS, Padova, Veneto, Italy., Fava P; Dermatologic Clinic, Department of Medical Sciences, University of Turin, Turin, Piemonte, Italy., Guidoboni M; Immunotherapy - Cell Therapy and Biobank, IRCCS-IRST, Meldola (FC), Italy., Depenni R; Department of Oncology and Hematology, University Hospital of Modena and Reggio Emilia, Modena, Emilia-Romagna, Italy., Minisini A; Department of Oncology, Azienda Sanitaria Universitaria del Friuli Centrale, Udine, Italy., Consoli F; Department of Oncology, ASST Spedali Civili, Brescia, Lombardia, Italy., Ascierto PA; Department of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy., Rinaldi G; UOC Oncologia Medica Aoup Paolo Giaccone, Palermo, Sicilia, Italy., Banzi M; Oncology Unit, Presidio Ospedaliero Arcispedale Santa Maria Nuova AUSL di Reggio Emilia - IRCCS, Reggio Emilia, Italy., Marconcini R; Presidio Ospedaliero S. Chiara - Az. Ospedaliero Universitaria Pisana, Pisa, Toscana, Italy., Gueli R; Medical Oncology, ASST Sette Laghi, Circolo Hospital and Macchi Foundation, Varese, Lombardia, Italy., Ferraresi V; Sarcomas and Rare Tumors Unit, IRCCS - Regina Elena National Cancer Institute, Rome, Lazio, Italy., Tucci M; Department of Biomedical Sciences and Clinical Oncology, University of Bari, 'Aldo Moro,' Bari, Italy., Tonini G; Department of Medical Oncology, University Campus Bio-Medico, Rome, Italy., Lo Re G; Medical Oncology and Immune-Related Tumors, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy., Guida M; Rare Tumors and Melanoma Unit, IRCCS Istituto dei Tumori Giovanni Paolo II, Bari, Italy., Del Vecchio M; Unit of Melanoma Medical Oncology, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Lombardia, Italy., Marcon IG; Novartis Farma S.p.A, Origgio, Lombardia, Italy., Queirolo P; Oncology Division, Policlinico San Martino IRCCS, Genova, Liguria, Italy.; Division of Medical Oncology for Melanoma, Sarcoma, and Rare Tumors, IEO, European Institute of Oncology IRCCS, Milan, Italy.

Publikováno v: Tumori [Tumori] 2023 Dec; Vol. 109 (6), pp. 537-545. Date of Electronic Publication: 2023 Jul 07.