Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marco T Nuñez"'
Publikováno v:
American Journal of Physiology-Cell Physiology. 323:C1791-C1806
Iron absorption is a complex and highly controlled process where DMT1 transports nonheme iron through the brush-border membrane of enterocytes to the cytoplasm but does not transport alkaline-earth metals such as calcium. However, it has been propose
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218123 (2019)
Iron is essential for the normal development of cellular processes. This metal has a high redox potential that can damage cells and its overload or deficiency is related to several diseases, therefore it is crucial for its absorption to be highly reg
Externí odkaz:
https://doaj.org/article/65bbb545ad4a4745a0148caeee954b75
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169601 (2017)
Iron is a trace metal, key for the development of living organisms. Its absorption process is complex and highly regulated at the transcriptional, translational and systemic levels. Recently, the internalization of the DMT1 transporter has been propo
Externí odkaz:
https://doaj.org/article/5f56e1ce59a945f7b2259e720d050167
Autor:
Marco T. Nuñez, Pedro Chana-Cuevas
Publikováno v:
Pharmaceuticals, Vol 11, Iss 4, p 109 (2018)
Iron chelation has been introduced as a new therapeutic concept for the treatment of neurodegenerative diseases with features of iron overload. At difference with iron chelators used in systemic diseases, effective chelators for the treatment of neur
Externí odkaz:
https://doaj.org/article/5b96f86952234ed7975343b68d67715a
Publikováno v:
Biological Research, Vol 33, Iss 2, Pp 133-142 (2000)
Cells tightly regulate iron levels through the activity of iron regulatory proteins (IRPs) that bind to RNA motifs called iron responsive elements (IREs). When cells become iron-depleted, IRPs bind to IREs present in the mRNAs of ferritin and the tra
Externí odkaz:
https://doaj.org/article/9392a7d8bc2a468cb69c02d5aae7e305
Autor:
Marisol, Gómez, Margarita E, Aliaga, Verónica, Arancibia, Alexis, Moya, Camilo, Segura, Marco T, Nuñez, Pabla, Aguirre, Edgar, Nagles, Olimpo, García-Beltrán
Publikováno v:
RSC advances. 8(55)
A new probe (
Publikováno v:
Free Radical Biology and Medicine. 120:S146
Physiological levels of ROS are important for several processes in the nervous system, ranging from neuronal precursors proliferation, to axonal guidance and neurotransmission. ROS also support neurite outgrowth and axonal specification, but the mech
Autor:
Cegarra, Layimar1,2, Colins, Andrea1, Gerdtzen, Ziomara P.2, Nuñez, Marco T.3, Salgado, J. Cristian1,2 jsalgado@ing.uchile.cl
Publikováno v:
PLoS ONE. 6/10/2019, Vol. 14 Issue 6, p1-26. 26p.
Autor:
Colins, Andrea1, Gerdtzen, Ziomara P.2, Nuñez, Marco T.3, Salgado, J. Cristian1,2 jsalgado@ing.uchile.cl
Publikováno v:
PLoS ONE. 1/10/2017, Vol. 12 Issue 1, p1-24. 24p.
Publikováno v:
Canadian Journal of Physiology & Pharmacology. May2013, Vol. 91 Issue 5, p338-345. 8p. 2 Color Photographs, 1 Diagram, 1 Chart, 1 Graph.