Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Marco T, Radukic"'
Publikováno v:
ACS synthetic biology. 11(11)
Virus-like particles (VLPs) have been used for numerous pharmaceutical applications, particularly vaccination and drug delivery. Recombinant adeno-associated virus (rAAV), a leading candidate in gene therapy, has been proposed as a vaccine scaffold,
Autor:
Miriam S. Epping, Anke Hummel, Marco T. Radukic, Martina Viefhues, Severin Wedde, Armin Grundmann, Harald Gröger
Publikováno v:
Analytical and Bioanalytical Chemistry
Whole-cell biocatalysts are versatile tools in (industrial) production processes; though, the effects that impact the efficiency are not fully understood yet. One main factor that affects whole-cell biocatalysts is the surrounding medium, which often
The vaccine ChAdOx1 nCoV-19 has been widely used, but its purity has been disputed because of rare side effects. We used Nanopore sequencing to assess the sequence and genetic purity of a vaccine dose. As we were lacking a reference sequence for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d730746f77bcd088df52ac2cafbc390
https://doi.org/10.21203/rs.3.rs-799338/v1
https://doi.org/10.21203/rs.3.rs-799338/v1
Publikováno v:
NAR Genomics and Bioinformatics
Next-generation sequencing of single-stranded DNA (ssDNA) enables transgene characterization of gene-therapy vectors such as adeno-associated virus (AAV), but current library generation uses complicated and potentially biased second-strand synthesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff1c0c7cbda3458ea8f80429dc589dc
https://doi.org/10.1101/2019.12.27.885319
https://doi.org/10.1101/2019.12.27.885319