Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Marco T, Núñez"'
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 196 (2024)
Ferroptosis is an iron-dependent cell death pathway that involves the depletion of intracellular glutathione (GSH) levels and iron-mediated lipid peroxidation. Ferroptosis is experimentally caused by the inhibition of the cystine/glutamate antiporter
Externí odkaz:
https://doaj.org/article/adeba5054ea6414aa2cb9afdc4a22958
Autor:
Silvia Gleitze, Omar A. Ramírez, Ignacio Vega-Vásquez, Jing Yan, Pedro Lobos, Hilmar Bading, Marco T. Núñez, Andrea Paula-Lima, Cecilia Hidalgo
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 705 (2023)
Ferroptosis, a newly described form of regulated cell death, is characterized by the iron-dependent accumulation of lipid peroxides, glutathione depletion, mitochondrial alterations, and enhanced lipoxygenase activity. Inhibition of glutathione perox
Externí odkaz:
https://doaj.org/article/7e44a1aca8de4abd84363887a9a07e2c
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 214 (2023)
Protein aggregation, mitochondrial dysfunction, iron dyshomeostasis, increased oxidative damage and inflammation are pathognomonic features of Parkinson’s disease (PD) and other neurodegenerative disorders characterized by abnormal iron accumulatio
Externí odkaz:
https://doaj.org/article/1d7d30cd1951413a87391120ce20c221
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 5, Pp 1003-1004 (2022)
Externí odkaz:
https://doaj.org/article/64556740e85a457bbd95b007af46c14e
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1807 (2022)
Selective regional iron accumulation is a hallmark of several neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. The underlying mechanisms of neuronal iron dyshomeostasis have been studied, mainly in a gene-by-gene
Externí odkaz:
https://doaj.org/article/88154fda5feb418081958e0ba9cdc27b
Publikováno v:
Free Radical Biology and Medicine. 175:28-41
Iron, through its participation in oxidation/reduction processes, is essential for the physiological function of biological systems. In the brain, iron is involved in the development of normal cognitive functions, and its lack during development caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6592e6f86ffe0dfd2f519ca225b91c
https://doi.org/10.1016/j.freeradbiomed.2021.08.231
https://doi.org/10.1016/j.freeradbiomed.2021.08.231
Autor:
Olimpo García-Beltrán, Natalia P Mena, Pabla Aguirre, Germán Barriga-González, Antonio Galdámez, Edgar Nagles, Tatiana Adasme, Cecilia Hidalgo, Marco T Núñez
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189043 (2017)
Iron accumulation, oxidative stress and calcium signaling dysregulation are common pathognomonic signs of several neurodegenerative diseases, including Parkinson´s and Alzheimer's diseases, Friedreich ataxia and Huntington's disease. Given their the
Externí odkaz:
https://doaj.org/article/07513b7a3cd840afac3e9920a4d04929
Autor:
Olimpo García-Beltrán, Bruce K. Cassels, Claudio Pérez, Natalia Mena, Marco T. Núñez, Natalia P. Martínez, Paulina Pavez, Margarita E. Aliaga
Publikováno v:
Sensors, Vol 14, Iss 1, Pp 1358-1371 (2014)
Two new coumarin-based “turn-off” fluorescent probes, (E)-3-((3,4-dihydroxybenzylidene)amino)-7-hydroxy-2H-chromen-2-one (BS1) and (E)-3-((2,4-dihydroxybenzylidene)amino)-7-hydroxy-2H-chromen-2-one (BS2), were synthesized and their detection of c
Externí odkaz:
https://doaj.org/article/16965f69964a46bdb99809358921d1bf
Publikováno v:
Parkinson's Disease, Vol 2016 (2016)
Mitochondrial dysfunction, iron accumulation, and oxidative damage are conditions often found in damaged brain areas of Parkinson’s disease. We propose that a causal link exists between these three events. Mitochondrial dysfunction results not only
Externí odkaz:
https://doaj.org/article/496d35d3cc13478194e66efdbdd3c20e
Autor:
Camilo Segura, Osvaldo Yañez, Antonio Galdámez, Victoria Tapia, Marco T. Núñez, Igor Osorio-Román, Camilo García, Olimpo García-Beltrán
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 434:114278
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db35f557a8674146d6488af5ad0ea48e
https://doi.org/10.1016/j.jphotochem.2022.114278
https://doi.org/10.1016/j.jphotochem.2022.114278