Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marco Strohmeier"'
Publikováno v:
A Lifecycle Approach to Knowledge Excellence in the Biopharmaceutical Industry ISBN: 9781315368337
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5384569a98efad939b4cc5b8d8fd013b
https://doi.org/10.1201/9781315368337-32
https://doi.org/10.1201/9781315368337-32
Autor:
Marco Strohmeier, Volker Windeisen, Irmgard Sinning, Gwyndaf Evans, Matthew J. Rodrigues, Steven E. Ealick, Yang Zhang, Jeremiah Hanes, Ivo Tews, Tadhg P. Begley, Gabriela Guédez, Antoine Royant, Stefan Fabian Weber
Publikováno v:
Nature Chemical Biology
Nature Chemical Biology, Nature Publishing Group, 2017, 13 (3), pp.290-294. ⟨10.1038/nchembio.2273⟩
Nature Chemical Biology, 2017, 13 (3), pp.290-294. ⟨10.1038/nchembio.2273⟩
Nature Chemical Biology, Nature Publishing Group, 2017, 13 (3), pp.290-294. ⟨10.1038/nchembio.2273⟩
Nature Chemical Biology, 2017, 13 (3), pp.290-294. ⟨10.1038/nchembio.2273⟩
International audience; Substrate channeling has emerged as a common mechanism for enzymatic intermediate transfer. A conspicuous gap in knowledge concerns the use of covalent lysine imines in the transfer of carbonyl-group-containing intermediates,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34970f0c3eeef2d7aad4fa6584bb26f0
https://hal.univ-grenoble-alpes.fr/hal-01487798/document
https://hal.univ-grenoble-alpes.fr/hal-01487798/document
Autor:
Ivo Tews, Marco Strohmeier, Silvia Wallner, Peter Macheroux, Sigrid Deller, Irmgard Sinning, Karsten Rippe, Martina Neuwirth, Volker Windeisen
Publikováno v:
FEBS Letters. 583:2179-2186
The universal enzymatic cofactor vitamin B6 can be synthesized as pyridoxal 5-phosphate (PLP) by the glutamine amidotransferase Pdx1. We show that Saccharomyces cerevisiae Pdx1 is hexameric by analytical ultracentrifugation and by crystallographic 3D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea1dc86e3de75146a9b78c8b9d0a183
https://doi.org/10.1016/j.febslet.2009.06.009
https://doi.org/10.1016/j.febslet.2009.06.009
Autor:
Ivo Tews, Karlheinz Flicker, Marco Strohmeier, Barbara Kappes, Peter Macheroux, Martina Neuwirth
Publikováno v:
Journal of Molecular Biology. 374:732-748
Pyridoxal 5'-phosphate (PLP) is required as a cofactor by many enzymes. The predominant de novo biosynthetic route is catalyzed by a heteromeric glutamine amidotransferase consisting of the synthase subunit Pdx1 and the glutaminase subunit Pdx2. Prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2a717963a4f688d12688aa3790d814
https://doi.org/10.1016/j.jmb.2007.09.038
https://doi.org/10.1016/j.jmb.2007.09.038
Publikováno v:
Biochemistry. 46:5131-5139
Two biosynthetic routes for the synthesis of pyridoxal 5'-phosphate (PLP), the biologically active compound of vitamin B6, have been characterized. The major pathway leads to direct formation of PLP from a pentasaccharide and a trisaccharide and is o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b3e5391d069a3c03379b74ae399bb0
https://doi.org/10.1021/bi602602x
https://doi.org/10.1021/bi602602x
Autor:
Ivo Tews, Thomas Raschle, Marco Strohmeier, Karsten Rippe, Jacek Mazurkiewicz, Thérésa Bridget Fitzpatrick, Irmgard Sinning
Publikováno v:
Proceedings of the National Academy of Sciences, Vol. 103, No 51 (2006) pp. 19284-9
Vitamin B 6 is an essential metabolic cofactor that has more functions in humans than any other single nutrient. Its de novo biosynthesis occurs through two mutually exclusive pathways that are absent in animals. The predominant pathway found in most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528cae52cfd0ca9eab767aa922781906
https://archive-ouverte.unige.ch/unige:89534
https://archive-ouverte.unige.ch/unige:89534
Autor:
Andrew J. Harvey, Jürgen Pleiss, Geoffrey B. Fincher, Maria Hrmova, Markus Fischer, Marco Strohmeier
Publikováno v:
Protein science : a publication of the Protein Society. 13(12)
Family GH16 glycoside hydrolases can be assigned to five subgroups according to their substrate specificities, including xyloglucan transglucosylases/hydrolases (XTHs), (1,3)-beta-galactanases, (1,4)-beta-galactanases/kappa-carrageenases, "nonspecifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f52c1325e4095e4f859fc9f1efec515
https://pubmed.ncbi.nlm.nih.gov/15557263
https://pubmed.ncbi.nlm.nih.gov/15557263