Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marco Schlepütz"'
Autor:
Anouk Oldenburger, Gerald Birk, Marco Schlepütz, Andre Broermann, Birgit Stierstorfer, Steven S. Pullen, Jörg F. Rippmann
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract Fibrotic processes in the liver of non‐alcoholic steatohepatitis (NASH) patients cause microcirculatory dysfunction in the organ which increases blood vessel resistance and causes portal hypertension. Assessing blood vessel function in the
Externí odkaz:
https://doaj.org/article/8d0ef998b8d645d1824e8fb9eae616b3
Autor:
Verena A Lambermont, Marco Schlepütz, Constanze Dassow, Peter König, Luc J Zimmermann, Stefan Uhlig, Boris W Kramer, Christian Martin
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e97610 (2014)
Animal models should display important characteristics of the human disease. Sheep have been considered particularly useful to study allergic airway responses to common natural antigens causing human asthma. A rationale of this study was to establish
Externí odkaz:
https://doaj.org/article/0020c9b07b894112a080596d81f58ef8
Autor:
Marco Schlepütz, Annette D Rieg, Sophie Seehase, Jan Spillner, Alberto Perez-Bouza, Till Braunschweig, Thomas Schroeder, Marc Bernau, Verena Lambermont, Christina Schlumbohm, Katherina Sewald, Rüdiger Autschbach, Armin Braun, Boris W Kramer, Stefan Uhlig, Christian Martin
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47344 (2012)
The peripheral airway innervation of the lower respiratory tract of mammals is not completely functionally characterized. Recently, we have shown in rats that precision-cut lung slices (PCLS) respond to electric field stimulation (EFS) and provide a
Externí odkaz:
https://doaj.org/article/e2c7cfbae4404c5c832da3ab336fd7ac
Autor:
Irene H. Heijink, Patrick van Rijn, Gwenda F Vasse, Janette K. Burgess, Mehmet Nizamoglu, Barbro N. Melgert, M.J. Thomas, Marco Schlepütz
Publikováno v:
The Journal of Pathology
Fibrosis results from aberrant wound healing and is characterized by an accumulation of extracellular matrix, impairing the function of an affected organ. Increased deposition of extracellular matrix proteins, disruption of matrix degradation, but al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d21d73a8de191421c4cf6b421ba8b15
https://doi.org/10.1002/path.5632
https://doi.org/10.1002/path.5632
Autor:
Sven O. Dahms, Gisela Schnapp, Martin Winter, Frank H. Büttner, Marco Schlepütz, Christian Gnamm, Alexander Pautsch, Hans Brandstetter
Publikováno v:
ACS chemical biology. 17(4)
Inhibitors of the proprotein convertase furin might serve as broad-spectrum antiviral therapeutics. High cellular potency and antiviral activity against acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported for (3,5-dichlorophenyl)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94031702d81f07bf8302792eab924e3
https://pubmed.ncbi.nlm.nih.gov/35377598
https://pubmed.ncbi.nlm.nih.gov/35377598
Autor:
Eric Simon, Koert P. de Jong, Paul Nicklin, Marco Schlepütz, Emilia Gore, Peter Olinga, Miriam Boersema, Anouk Oldenburger, Jörg F. Rippmann, H. S. Hofker, Matthias Zwick, Emilia Bigaeva
Publikováno v:
Archives of toxicology, 93(12), 3549-3583. SPRINGER HEIDELBERG
Our knowledge of complex pathological mechanisms underlying organ fibrosis is predominantly derived from animal studies. However, relevance of animal models for human disease is limited; therefore, an ex vivo model of human precision-cut tissue slice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfe554fcf4c606e9e5175ae57f0a5eb
https://hdl.handle.net/11370/19b4a6de-42b7-4860-aa41-0b2c847c0d3c
https://hdl.handle.net/11370/19b4a6de-42b7-4860-aa41-0b2c847c0d3c
Autor:
Andre Broermann, Birgit Stierstorfer, Steven S. Pullen, Marco Schlepütz, Gerald Birk, Anouk Oldenburger, Jörg F. Rippmann
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 3, Pp n/a-n/a (2021)
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives
Fibrotic processes in the liver of non‐alcoholic steatohepatitis (NASH) patients cause microcirculatory dysfunction in the organ which increases blood vessel resistance and causes portal hypertension. Assessing blood vessel function in the liver is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513143c82ae7f08c521d073a3cd0f6d7
https://doi.org/10.1002/prp2.768
https://doi.org/10.1002/prp2.768
Publikováno v:
Airway pharmacology and treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dbdf43df05121505b05af2302f44674
https://doi.org/10.1183/13993003.congress-2019.pa4205
https://doi.org/10.1183/13993003.congress-2019.pa4205
Publikováno v:
ERS Lung Science Conference 2016.
The lung is perennially challenged by inflammatory stimuli. We hypothesize that pulmonary inflammation follows a modular concept, in which the mediator profile determines whether inflammation remains salutary or escalates into organ dysfunction. Some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec608a126d1e674c9f96eb0b731398c
https://doi.org/10.1183/13993003.congress-2016.pp223
https://doi.org/10.1183/13993003.congress-2016.pp223
Publikováno v:
3.2 Airway Cell Biology and Immunopathology.
Asthma is associated with chronic inflammation and episodes of exacerbations, which are often triggered by viral or bacterial infections. Toll-like receptors (TLRs) play a pivotal role in the innate immune response to invading pathogens. Precision-cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1722efe11c6c10621da3876e80b7767
https://doi.org/10.1183/13993003.congress-2016.pa3991
https://doi.org/10.1183/13993003.congress-2016.pa3991