Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marco Schaaf"'
Autor:
Odeta Meçe, Diede Houbaert, Maria-Livia Sassano, Tania Durré, Hannelore Maes, Marco Schaaf, Sanket More, Maarten Ganne, Melissa García-Caballero, Mila Borri, Jelle Verhoeven, Madhur Agrawal, Kathryn Jacobs, Gabriele Bergers, Silvia Blacher, Bart Ghesquière, Mieke Dewerchin, Johan V. Swinnen, Stefan Vinckier, María S. Soengas, Peter Carmeliet, Agnès Noël, Patrizia Agostinis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Autophagy is essential to endothelial cell homeostasis. Here the authors show that lipophagy in LEC supports fatty acid oxidation to sustain a mitochondrial-Prox1 gene expression circuit and promote response of LEC to lymphangiogenic mediators.
Externí odkaz:
https://doaj.org/article/6f053768112c4a3e957fc921d9943221
Autor:
Abhishek D. Garg, Monica Vara Perez, Marco Schaaf, Patrizia Agostinis, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi
Publikováno v:
OncoImmunology, Vol 6, Iss 7 (2017)
Dendritic cell (DC)-based vaccines against cancer have been extensively developed over the past two decades. Typically DC-based cancer immunotherapy entails loading patient-derived DCs with an appropriate source of tumor-associated antigens (TAAs) an
Externí odkaz:
https://doaj.org/article/e66c072e6d3e4ac9bbc1e7e6958fa25d
Autor:
Abhishek D. Garg, Lien Vandenberk, Matthias Van Woensel, Jochen Belmans, Marco Schaaf, Louis Boon, Steven De Vleeschouwer, Patrizia Agostinis
Publikováno v:
OncoImmunology, Vol 6, Iss 4 (2017)
Glioblastoma (GBM) is resistant to most multimodal therapies. Clinical success of immune-checkpoint inhibitors (ICIs) has spurred interest in applying ICIs targeting CTLA4, PD1 or IDO1 against GBM. This amplifies the need to ascertain GBM's intrinsic
Externí odkaz:
https://doaj.org/article/3a0cee7e7812429bb36bd26111abdbdf
Publikováno v:
Frontiers in Oncology, Vol 6 (2016)
Autophagy is best known as a lysosomal degradation and recycling pathway to maintain cellular homeostasis. During autophagy, cytoplasmic content is recognized and packed in autophagic vacuoles, or autophagosomes, and targeted for degradation. However
Externí odkaz:
https://doaj.org/article/f3d96cb2145d43d08a344c4b7d7e6bc1
Autor:
Judith Feinberg, Robert Stansbury, Marco Schaaf, Anina Aaron, Ira Sharma, Patrick J. Strollo, Nathan Pauly
Publikováno v:
J Clin Sleep Med
STUDY OBJECTIVES: To assess the prevalence rates of sleep-disordered breathing (SDB) in a high-risk and rural-dwelling Medicaid population with significant comorbidities. METHODS: Our study analyzed anonymized administrative claims data from West Vir
Autor:
Odeta Mece, Diede Houbaert, Tania Durré, Hannelore Maes, Marco Schaaf, Sanket More, Maarten Ganne, Melissa García-Caballero, Mila Borri, Jelle Verhoeven, Silvia Blacher, Bart Ghesquière, Mieke Dewerchin, Johannes Swinnen, Stefan Vinckier, Maria Soengas, Peter Carmeliet, Agnès Noel, Patrizia Agostinis
Autophagy has an emerging vasculoprotective role but whether and how it regulates lymphatic endothelial cells (LEC) and lymphangiogenesis is unknown. Here, we show that genetic deficiency of autophagy in LEC impairs the responses to VEGF-C and injury
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3d831b67d98d927664879d691c11830
https://doi.org/10.21203/rs.3.rs-403701/v1
https://doi.org/10.21203/rs.3.rs-403701/v1