Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marco S.L. Alves"'
Autor:
Simone Van der Sander Lee, Jefferson Luiz Brum Marques, Roberto Léo da Silva, Sandra Cossul, Thaís Rossoni Weber, Marco S.L. Alves
Publikováno v:
Revista Portuguesa de Cardiologia, Vol 40, Iss 10, Pp 757-765 (2021)
Resumo: Fundamento: Diabetes mellitus tipo 1 (DM1) é uma doença crônica com pico de incidência na adolescência, com grande impacto na morbimortalidade, principalmente cardiovascular. A cardiomiopatia diabética caracteriza‐se por lesões estru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fd504cea450f2c7739c998bb27bc9f
https://doi.org/10.1016/j.repc.2020.11.012
https://doi.org/10.1016/j.repc.2020.11.012
Autor:
Roberto Léo da Silva, Marco S.L. Alves, Jefferson Luiz Brum Marques, Sandra Cossul, Thaís Rossoni Weber, Simone Van der Sander Lee
Publikováno v:
Revista portuguesa de cardiologia. 40(10)
Introduction Type 1 diabetes (T1D) is a chronic disease with peak incidence in adolescence; it has a major impact on morbidity and mortality, especially cardiovascular. Diabetic cardiomyopathy is characterized by structural and functional lesions in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3146404db172109a0b29914da965c4
https://pubmed.ncbi.nlm.nih.gov/34857115
https://pubmed.ncbi.nlm.nih.gov/34857115
Autor:
Robert D. Gaffin, Beata M. Wolska, Jillian N. Simon, Eric M. Montminy, R. John Solaro, David F. Wieczorek, Chad M. Warren, Marco S.L. Alves
Publikováno v:
Cardiovascular Research. 113:915-925
Background Dilated cardiomoypathies (DCM) are a heterogeneous group of inherited and acquired diseases characterized by decreased contractility and enlargement of cardiac chambers and a major cause of morbidity and mortality. Mice with Glu54Lys mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506201a9ac2c09bc83710c3c176e7243
https://doi.org/10.1093/cvr/cvx068
https://doi.org/10.1093/cvr/cvx068
Publikováno v:
Journal of Molecular and Cellular Cardiology. 48:834-842
Cardiomyopathies are a heterogeneous group of diseases of the myocardium associated with mechanical and/or electrical dysfunction that frequently show inappropriate ventricular hypertrophy or dilation. Current data suggest that numerous mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdaf2bec25ef9db4aaef47df0c3d6c7
https://doi.org/10.1016/j.yjmcc.2010.01.003
https://doi.org/10.1016/j.yjmcc.2010.01.003
Autor:
Eduardo Doubrawa, Acir Rachid, Francisco Luiz Gomide Mafra Magalhães, Marco S.L. Alves, Marister Malvezzi, M.M. Oliveira, Nelson Neto, Salun Coelho Aragão
Publikováno v:
Revista Brasileira de Reumatologia. 44:383-389
A linfohistiocitose hemofagocitica caracteriza-se por ativacao e proliferacao excessiva de linfocitos e macrofagos. Quando associada a artrite idiopatica juvenil e tambem conhecida por "sindrome de ativacao do macrofago", sendo uma complicacao potenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf3899b1f64c8c53339b2d6e368ab4ce
https://doi.org/10.1590/s0482-50042004000500013
https://doi.org/10.1590/s0482-50042004000500013
Autor:
Aaron C. Hinken, Chad M. Warren, R. John Solaro, Fernando Augusto Lavezzo Dias, David F. Wieczorek, Megan S. Utter, Brandon J. Biesiadecki, Eric M. Montminy, Sakthivel Sadayappan, Beata M. Wolska, Jillian N. Simon, Robert D. Gaffin, Marco S.L. Alves, rd Robert T. Davis, Jeffrey Robbins
Publikováno v:
Circulation. Cardiovascular genetics. 7(2)
Background— Hypertrophic cardiomyopathy (HCM) is a common genetic disorder caused mainly by mutations in sarcomeric proteins and is characterized by maladaptive myocardial hypertrophy, diastolic heart failure, increased myofilament Ca 2+ sensitivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf59e3aa0ae082292113101997c8aca9
https://pubmed.ncbi.nlm.nih.gov/24585742
https://pubmed.ncbi.nlm.nih.gov/24585742
Autor:
Lynley S. Heinrich, Marco S.L. Alves, Fernando Augusto Lavezzo Dias, Beata M. Wolska, David F. Wieczorek, Shamim A. K. Chowdhury, James R. Peña, Paul H. Goldspink, Robert D. Gaffin, Evangelia G. Kranias
Publikováno v:
Journal of molecular and cellular cardiology. 51(5)
We have recently shown that a temporary increase in sarcoplasmic reticulum (SR) cycling via adenovirus-mediated overexpression of sarcoplasmic reticulum ATPase (SERCA2) transiently improves relaxation and delays hypertrophic remodeling in a familial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfdd536a14d6c9d187417fa6f940009
https://pubmed.ncbi.nlm.nih.gov/21840315
https://pubmed.ncbi.nlm.nih.gov/21840315
Autor:
Andrew B. Herr, Ilona Bodi, Ganapathy Jagatheesan, Dipak K. Dube, R. John Solaro, Arnold M. Schwartz, Marco S.L. Alves, Beata M. Wolska, Natalia Petrashevskaya, Sudarsan Rajan, Roger Hullin, Chehade N. Karam, Stephen B. Liggett, Christian F. Bulcao, David F. Wieczorek, Greg P. Boivin, Shahab A. Akhter, Karen M. D'Souza
Publikováno v:
Circulation, vol. 121, no. 3, pp. 410-418
Background— Tropomyosin (TM), an essential actin-binding protein, is central to the control of calcium-regulated striated muscle contraction. Although TPM1α (also called α-TM) is the predominant TM isoform in human hearts, the precise TM isoform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13888fddce78325afffc51846fc704f6
https://pubmed.ncbi.nlm.nih.gov/20100986
https://pubmed.ncbi.nlm.nih.gov/20100986
Autor:
Corrado Poggesi, Beata M. Wolska, Chiara Tesi, R. John Solaro, Beatrice Scellini, Marco S.L. Alves, Brandon J. Biesiadecki, David F. Wieczorek, Ganapathy Jagatheesan, Jonathan P. Davis, Bin Liu
Publikováno v:
Biophysical Journal. (3):350a
Tropomyosin contains a phosphorylation site at Ser-283 located within the head-to-tail overlap region that regulates muscle contraction. Previously we demonstrated that recombinant wild-type (Tm-WT) and pseudo-phosphorylated (Tm-S283D) alpha tropomyo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70019cfa7dcd15f304d9ae3469d76a5e
Autor:
Sudarsan Rajan, R. John Solaro, Beata M. Wolska, Eric M. Montminy, David F. Wieczorek, Chad M. Warren, Robert D. Gaffin, Jillian N. Simon, Marco S.L. Alves
Publikováno v:
Biophysical Journal. (3):560a
Dilated cardiomoypathy (DCM) is a disease characterized by decreased contractility and enlargement of cardiac chambers. We have previously shown that E54K mutation in α-tropomyosin (TM54) reduces myofilament Ca+2 sensitivity and causes DCM. Thus, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1d83750d6d245789c8650ce1c92538