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Intravital & laser speckle investigations of the role of interleukin36 in myocardial ischaemia reperfusion injury; a new therapeutic target for the aged heart

Autor: Juma El-awaisi, Dean Kavanagh, Marco Rink, Chris Weston, Nigel Drury, Neena Kalia

Publikováno v: Cardiovascular Research. 118

Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): British Heart Foundation Introduction Whilst blood flow restoration is critical following myocardial infarction (MI), ischemia-reperfusion injury (IRI) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7409e2075c57f4f84dc30139d7961b2
https://doi.org/10.1093/cvr/cvac066.051

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Targeting IL-36 improves age-related coronary microcirculatory dysfunction and attenuates myocardial ischemia/reperfusion injury in mice

Autor: Dean Kavanagh, Chris Weston, Marco Rink, Juma El-Awaisi, NEENA KALIA, Nigel Drury

Publikováno v: JCI Insight. 7

Following myocardial infarction (MI), elderly patients have a poorer prognosis than younger patients, which may be linked to increased coronary microvessel susceptibility to injury. Interleukin-36 (IL-36), a newly discovered proinflammatory member of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbce3e07745ce720b87213398aff26bd
https://doi.org/10.1172/jci.insight.155236

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