Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device

Autor: Brian D. Reed, Michael J. Meyer, Valentin Abramzon, Omer Ad, Pat Adcock, Faisal R. Ahmad, Gün Alppay, James A. Ball, James Beach, Dominique Belhachemi, Anthony Bellofiore, Michael Bellos, Juan Felipe Beltrán, Andrew Betts, Mohammad Wadud Bhuiya, Kristin Blacklock, Robert Boer, David Boisvert, Norman D. Brault, Aaron Buxbaum, Steve Caprio, Changhoon Choi, Thomas D. Christian, Robert Clancy, Joseph Clark, Thomas Connolly, Kathren Fink Croce, Richard Cullen, Mel Davey, Jack Davidson, Mohamed M. Elshenawy, Michael Ferrigno, Daniel Frier, Saketh Gudipati, Stephanie Hamill, Zhaoyu He, Sharath Hosali, Haidong Huang, Le Huang, Ali Kabiri, Gennadiy Kriger, Brittany Lathrop, An Li, Peter Lim, Stephen Liu, Feixiang Luo, Caixia Lv, Xiaoxiao Ma, Evan McCormack, Michele Millham, Roger Nani, Manjula Pandey, John Parillo, Gayatri Patel, Douglas H. Pike, Kyle Preston, Adeline Pichard-Kostuch, Kyle Rearick, Todd Rearick, Marco Ribezzi-Crivellari, Gerard Schmid, Jonathan Schultz, Xinghua Shi, Badri Singh, Nikita Srivastava, Shannon F. Stewman, TR Thurston, T. R. Thurston, Philip Trioli, Jennifer Tullman, Xin Wang, Yen-Chih Wang, Eric A. G. Webster, Zhizhuo Zhang, Jorge Zuniga, Smita S. Patel, Andrew D. Griffiths, Antoine M. van Oijen, Michael McKenna, Matthew D. Dyer, Jonathan M. Rothberg

Publikováno v: Science. 378:186-192

Studies of the proteome would benefit greatly from methods to directly sequence and digitally quantify proteins and detect posttranslational modifications with single-molecule sensitivity. Here, we demonstrate single-molecule protein sequencing using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d3367086ac787e208c4c79a68cbb83f
https://doi.org/10.1126/science.abo7651

Work extraction, information-content and the Landauer bound in the continuous Maxwell Demon

Autor: Marco Ribezzi-Crivellari, Felix Ritort

Publikováno v: Journal of Statistical Mechanics: Theory and Experiment

In a recent paper we have introduced a continuous version of the Maxwell demon (CMD) that is capable of extracting large amounts of work per cycle by repeated measurements of the state of the system. Here we underline its main features such as the ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52df5631b0b498c6929d72d462c44a1d

Elastic Properties of Nucleic Acids by Single-Molecule Force Spectroscopy

Autor: Joan Camunas-Soler, Marco Ribezzi-Crivellari, Felix Ritort

Publikováno v: Annual Review of Biophysics. 45:65-84

We review the current knowledge on the use of single-molecule force spectroscopy techniques to extrapolate the elastic properties of nucleic acids. We emphasize the lesser-known elastic properties of single-stranded DNA. We discuss the importance of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0561cf8876a2522d5742028c559325e0
https://doi.org/10.1146/annurev-biophys-062215-011158

Derivation of nearest-neighbor DNA parameters in magnesium from single-molecule experiments

Autor: Cristiano Valim Bizarro, Josep Maria Huguet, Marco Ribezzi-Crivellari, Felix Ritort

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Nucleic Acids Research

DNA hybridization is an essential molecular reaction in biology with many applications. The nearest-neighbor (NN) model for nucleic acids predicts DNA thermodynamics using energy values for the different base pair motifs. These values have been deriv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fcc1a8ae11dcfb7a07fc1bd0f1e01b9
http://hdl.handle.net/2445/125475

From free energy measurements to thermodynamic inference in nonequilibrium small systems

Autor: Felix Ritort, Anna Alemany, Marco Ribezzi-Crivellari

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname

Fluctuation theorems (FTs), such as the Crooks or Jarzynski equalities (JEs), have become an important tool in single-molecule biophysics where they allow experimentalists to exploit thermal fluctuations and measure free-energy differences from non-e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41ed93447101fd4a24c1ff20feeca03
http://hdl.handle.net/2445/101806