Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Marco Pontoglio"'
Autor:
Aurore Claude-Taupin, Pierre Isnard, Alessia Bagattin, Nicolas Kuperwasser, Federica Roccio, Biagina Ruscica, Nicolas Goudin, Meriem Garfa-Traoré, Alice Regnier, Lisa Turinsky, Martine Burtin, Marc Foretz, Marco Pontoglio, Etienne Morel, Benoit Viollet, Fabiola Terzi, Patrice Codogno, Nicolas Dupont
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Shear stress generated by urinary fluid flow is an important regulator of renal function. Its dysregulation is observed in various chronic and acute kidney diseases. Previously, we demonstrated that primary cilium-dependent autophagy allows
Externí odkaz:
https://doaj.org/article/e254472962f4442b9d2e6ee13c808669
Autor:
Pierre Isnard, Paul Vergnaud, Serge Garbay, Matthieu Jamme, Maeva Eloudzeri, Alexandre Karras, Dany Anglicheau, Valérie Galantine, Arwa Jalal Eddine, Clément Gosset, Franck Pourcine, Mohammed Zarhrate, Jean-Baptiste Gibier, Elena Rensen, Stefano Pietropaoli, Giovanna Barba-Spaeth, Jean-Paul Duong-Van-Huyen, Thierry J. Molina, Florian Mueller, Christophe Zimmer, Marco Pontoglio, Fabiola Terzi, Marion Rabant
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
Acute kidney injury is one of the most important complications in patients with COVID-19 and is considered a negative prognostic factor with respect to patient survival. The occurrence of direct infection of the kidney by SARS-CoV-2, and its contribu
Externí odkaz:
https://doaj.org/article/d5535bb2d784429fa9e74433c60f3cbf
Autor:
Zhen Miao, Michael S. Balzer, Ziyuan Ma, Hongbo Liu, Junnan Wu, Rojesh Shrestha, Tamas Aranyi, Amy Kwan, Ayano Kondo, Marco Pontoglio, Junhyong Kim, Mingyao Li, Klaus H. Kaestner, Katalin Susztak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Epigenetic and transcriptional dynamics are critical for both tissue homeostasis and injury response in the kidney. Leveraging a single cell multiomics atlas of the developing mouse kidney, the authors reveal key events in chromatin regulation and ge
Externí odkaz:
https://doaj.org/article/041359208fd74d1f952a6f800451b64e
Autor:
Martina Bonucci, Nicolas Kuperwasser, Serena Barbe, Vonda Koka, Delphine de Villeneuve, Chi Zhang, Nishit Srivastava, Xiaoying Jia, Matthew P. Stokes, Frank Bienaimé, Virginie Verkarre, Jean Baptiste Lopez, Fanny Jaulin, Marco Pontoglio, Fabiola Terzi, Benedicte Delaval, Matthieu Piel, Mario Pende
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
mTOR activation is known to generate polycystic kidneys, which show both increased proliferation and loss of oriented cell division (OCD). Here, Bonucci et al. show that loss of OCD is linked to S6K1 activation through its direct target Afadin and is
Externí odkaz:
https://doaj.org/article/7932503fbce7452fbc9e9d545274ef7a
Autor:
Aurélie Phelep, Denise Laouari, Kapil Bharti, Martine Burtin, Salvina Tammaccaro, Serge Garbay, Clément Nguyen, Florence Vasseur, Thomas Blanc, Sophie Berissi, Francina Langa-Vives, Evelyne Fischer, Anne Druilhe, Heinz Arnheiter, Gerard Friedlander, Marco Pontoglio, Fabiola Terzi
Publikováno v:
PLoS Genetics, Vol 13, Iss 12, p e1007093 (2017)
Congenital nephron number varies widely in the human population and individuals with low nephron number are at risk of developing hypertension and chronic kidney disease. The development of the kidney occurs via an orchestrated morphogenetic process
Externí odkaz:
https://doaj.org/article/6752b6f74c8d47d5b382dee7a6c03339
Autor:
Denise Laouari, Martine Burtin, Aurélie Phelep, Frank Bienaime, Laure‐Hélène Noel, David C. Lee, Christophe Legendre, Gérard Friedlander, Marco Pontoglio, Fabiola Terzi
Publikováno v:
EMBO Molecular Medicine, Vol 4, Iss 8, Pp 825-839 (2012)
Abstract The molecular networks that control the progression of chronic kidney diseases (CKD) are poorly defined. We have recently shown that the susceptibility to development of renal lesions after nephron reduction is controlled by a locus on mouse
Externí odkaz:
https://doaj.org/article/68b374ece3734a02a77a276f057bf70f
Supplementary Table 1 from A Genomic Map of p53 Binding Sites Identifies Novel p53 Targets Involved in an Apoptotic Network
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43093631885e977da4a4ecfde087740f
https://doi.org/10.1158/0008-5472.22363940
https://doi.org/10.1158/0008-5472.22363940
The transcriptional activity of the p53 protein is central to its role in tumor suppression. Identification of the complete repertoire of p53-regulated genes is critical for dissecting the complexity of the p53 network. Although several different app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e2b36e7174a052a2f067ed8c82d21c
https://doi.org/10.1158/0008-5472.c.6493952
https://doi.org/10.1158/0008-5472.c.6493952
Supplementary Tables 2-3 from A Genomic Map of p53 Binding Sites Identifies Novel p53 Targets Involved in an Apoptotic Network
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8765510e18e12a3344874947da343bfd
https://doi.org/10.1158/0008-5472.22363937
https://doi.org/10.1158/0008-5472.22363937
Autor:
ANA ACOSTA-MONTALVO, CHIARA SAPONARO, JULIEN THEVENET, MAGALI CHIRAL, ANTHONY PIRON, NATHALIE DELALLEAU, GIANNI PASQUETTI, ANAÏS CODDEVILLE, MARIA MORENO, VALERY GMYR, MIRIAM CNOP, JULIE A. KERR-CONTE, FRANCOIS PATTOU, MARCO PONTOGLIO, ADRIAN LISTON, CAROLINE BONNER
Publikováno v:
Diabetes. 71
Hepatocyte Nuclear Factor-1A (HNF1A) is a master regulator of key glucose-responsive genes in metabolic organs such as the intestine, liver, kidney, and pancreas. Heterozygous mutations in HNF1A cause Maturity-Onset-Diabetes-of-the-Young (HNF1A-MODY)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf5114a9fa5964052d9eeeb95d6c625b
https://doi.org/10.2337/db22-149-or
https://doi.org/10.2337/db22-149-or