Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marco Poleganov"'
Autor:
Valesca Bukur, Martin Löwer, Andreas Kuhn, Lena M. Kranz, Orlandini Von Niessen Alexandra, Marco Poleganov, Corina Rechner, Tim Beissert, Britta Vallazza, Mustafa Diken, Stephanie Fesser, Ugur Sahin, Arianne Plaschke, Özlem Türeci
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 27(4)
Synthetic mRNA has emerged as a powerful tool for the transfer of genetic information, and it is being explored for a variety of therapeutic applications. Many of these applications require prolonged intracellular persistence of mRNA to improve bioav
Autor:
Diana Barea Roldan, Isabell Burkhart, Brad Hamilton, Sarah Eminli, Marco Poleganov, Kevin Yi, Tim Beissert, Rosario Heck, Arianne Beyer, Ugur Sahin, Stephanie Herz, Jung-Il Moon, Johanna Goldmann, Özlem Türeci
Publikováno v:
Human Gene Therapy. 26:751-766
mRNA reprogramming results in the generation of genetically stable induced pluripotent stem (iPS) cells while avoiding the risks of genomic integration. Previously published mRNA reprogramming protocols have proven to be inconsistent and time-consumi
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 6:471-499
In recent years, the interest in using messenger RNA (mRNA) as a therapeutic means to tackle different diseases has enormously increased. This holds true not only for numerous preclinical studies, but mRNA has also entered the clinic to fight cancer.