Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Marco Pignatelli"'
Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior
Autor:
Juan L. Gomez, Jordi Bonaventura, Jacqueline Keighron, Kelsey M. Wright, Dondre L. Marable, Lionel A. Rodriguez, Sherry Lam, Meghan L. Carlton, Randall J. Ellis, Chloe J. Jordan, Guo-hua Bi, Oscar Solis, Marco Pignatelli, Michael J. Bannon, Zheng-Xiong Xi, Gianluigi Tanda, Michael Michaelides
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Cocaine binds to the dopamine (DA) transporter (DAT) to regulate cocaine reward and seeking behavior. Zinc (Zn2+) also binds to the DAT, but the in vivo relevance of this interaction is unknown. We found that Zn2+ concentrations in postmorte
Externí odkaz:
https://doaj.org/article/7c2c5e8de1754235a1d3f93bf616dd57
Autor:
Robert Nisticò, Dalila Mango, Georgia Mandolesi, Sonia Piccinin, Nicola Berretta, Marco Pignatelli, Marco Feligioni, Alessandra Musella, Antonietta Gentile, Francesco Mori, Giorgio Bernardi, Ferdinando Nicoletti, Nicola B Mercuri, Diego Centonze
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54666 (2013)
Abnormal use-dependent synaptic plasticity is universally accepted as the main physiological correlate of memory deficits in neurodegenerative disorders. It is unclear whether synaptic plasticity deficits take place during neuroinflammatory diseases,
Externí odkaz:
https://doaj.org/article/1fff451029b24956b5522a191751b724
Autor:
Carol A. Tamminga, Antonello Bonci, David J. Barker, Jocelyn Wu, Eric M. Parise, Leonardo Bontempi, Sissi Palma Ribeiro, Angélica Torres-Berrío, Alejandra Lopez, Marisela Morales, Marco Pignatelli, Hugo A. Tejeda, Mingshan Xue, Zhao-Lin Cai, Yocasta Alvarez-Bagnarol, Eric J. Nestler, Federica Lucantonio, Rosa Anna Maria Marino
Publikováno v:
Molecular Psychiatry
Stress promotes negative affective states, which include anhedonia and passive coping. While these features are in part mediated by neuroadaptations in brain reward circuitry, a comprehensive framework of how stress-induced negative affect may be enc
Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior
Autor:
Dondre L. Marable, Kelsey M. Wright, Michael J. Bannon, Lionel A. Rodriguez, Zheng-Xiong Xi, Jordi Bonaventura, Juan Gómez, Marco Pignatelli, Guo Hua Bi, Randall J. Ellis, Sherry Lam, Oscar Solis, Michael Michaelides, Gianluigi Tanda, Jacqueline D. Keighron, Meghan L. Carlton, Chloe J. Jordan
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Translational Psychiatry
Universidad de Barcelona
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Translational Psychiatry
Cocaine binds to the dopamine (DA) transporter (DAT) to regulate cocaine reward and seeking behavior. Zinc (Zn2+) also binds to the DAT, but the in vivo relevance of this interaction is unknown. We found that Zn2+ concentrations in postmortem brain (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1b7660b944fbfa906b0ed1b4b25373
http://hdl.handle.net/2445/189285
http://hdl.handle.net/2445/189285
Autor:
Kelsey M. Wright, Sherry Lam, Dondre L. Marable, Lionel A. Rodriguez, Juan Gómez, Michael J. Bannon, Chloe J. Jordan, Marco Pignatelli, Oscar Solis, Jacqueline D. Keighron, Jordi Bonaventura, Michael Michaelides, Guo Hua Bi, Gianluigi Tanda, Zheng-Xiong Xi, Randall J. Ellis, Meghan L. Carlton
Cocaine binds to the dopamine (DA) transporter (DAT) to regulate cocaine reward and seeking behavior. Zinc (Zn2+) also binds to the DAT, but thein vivorelevance of this interaction is unknown. We found that Zn2+concentrations in postmortem brain (cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df576d3f88a55eda9dc1ead2fbd656e9
https://doi.org/10.1101/2020.08.29.273482
https://doi.org/10.1101/2020.08.29.273482
Autor:
Wendy Xin, Roy A. Wise, Hui Shen, Antonello Bonci, Marco Pignatelli, Rosa Anna Maria Marino, Stephanie C. Gantz, Ross A. McDevitt
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Stimulation of lateral hypothalamic (LH) neurons produces eating in sated animals and increases activity of dopamine neurons. The present study shows that the activation of dopamine neurons failed to induce eating. Rather, food approach
Autor:
Julia Levinsson, Markus Heilig, Antonello Bonci, Carla Canal, Maarit Jaarola, Michael Fritz, Juan Hidalgo, Anna M. Klawonn, David Engblom, Johan Jakobsson, Hugo A. Tejeda, Silvia Castany, Marco Pignatelli, Fredrik Similä
Publikováno v:
Immunity. 54(2)
Microglia are activated in many neurological diseases and have been suggested to play an important role in the development of affective disorders including major depression. To investigate how microglial signaling regulates mood, we used bidirectiona
Autor:
Antonello Bonci, Marco Pignatelli
Publikováno v:
Neuron. 97(2)
Mesolimbic dopamine (DA) neurons play a central role in motivation and reward processing. Although the activity of these mesolimbic DA neurons is controlled by afferent inputs, little is known about the circuits in which they are embedded. Using retr
Autor:
Mikhail V. Pletnikov, Leslie A. Scarffe, Shaida A. Andrabi, Stewart Neifert, Xiling Yin, Ted M. Dawson, Valina L. Dawson, Cibele Canal Castro, David Valle, Joshua Crawford, Li Chen, Marco Pignatelli, Rong Chen, Erica Ma, Adam A. Behensky, Antonello Bonci, Noah Guiberson, Dimitrios Avramopoulos, Ann E. Pulver, Jin Wan Kim, Melissa Chang, George K.E. Umanah, Xiaobo Mao
Publikováno v:
Science Translational Medicine. 9
The AAA+ adenosine triphosphatase (ATPase) Thorase plays a critical role in controlling synaptic plasticity by regulating the expression of surface α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs). Bidirectional sequencing of
Autor:
Marisela Morales, Nicholas J Edwards, Hugo A. Tejeda, Caroline E. Bass, Marco Pignatelli, Bernhard Bettler, Shiliang Zhang, Antonello Bonci, Jocelyn Wu, Ross A. McDevitt
Publikováno v:
Nature Neuroscience
Inputs to midbrain dopamine neurons control rewarding and drug-related behaviors. The authors found that nucleus accumbens inputs and local GABA neurons inhibit dopamine neurons through distinct populations of GABA receptors. Furthermore, genetic del