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Differential maturation and chaperone dependence of the paralogous protein kinases DYRK1A and DYRK1B
Autor:
Marco Papenfuss, Svenja Lützow, Gerrit Wilms, Aaron Babendreyer, Maren Flaßhoff, Conrad Kunick, Walter Becker
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The HSP90/CDC37 chaperone system not only assists the maturation of many protein kinases but also maintains their structural integrity after folding. The interaction of mature kinases with the HSP90/CDC37 complex is governed by the conformat
Externí odkaz:
https://doaj.org/article/b25ecef2c6ec46788f3b38238ecb755f