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Autor:
Luísa Diogo, Lodewijk IJlst, Jos P.N. Ruiter, Margarida F. B. Silva, Paula Garcia, Rob Ofman, Isabel Tavares de Almeida, Marinus Duran, Marco Moedas, Ronald J.A. Wanders, Paula B.M. Luís
Publikováno v:
Biochemical pharmacology, 82(11), 1740-1746. Elsevier Inc.
Valproic acid (VPA) is a simple branched medium-chain fatty acid with expanding therapeutic applications beyond its prime anticonvulsant properties. Aims (1) To resolve the underlying basis for the interference of valproate with the isoleucine degrad