Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marco Merida"'
Autor:
Kimihiro Ohkubo, Marco Merida, Louis B. Hersh, James N. Baraniuk, Michael A. Kaliner, Robert J. Hohman
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background: Aminopeptidases activate bradykinin and degrade many inflammatory peptides. Objective: The objective of this study was to identify the types of aminopeptidase activities in human nasal mucosa. Methods: Human nasal mucosa was homogenized (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61d4422cc034fa2f2605091f1e9f262
https://doi.org/10.1016/s0091-6749(98)70013-2
https://doi.org/10.1016/s0091-6749(98)70013-2
Autor:
Robert J. Hohman, Helen C. Kaulbach, Kimihiro Ohkubo, James N. Baraniuk, Michael A. Kaliner, Jeffrey N. Hausfeld, Marco Merida
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 9:557-567
Neutral endopeptidase (E.C.3.4.24.11, enkephalinase, NEP) is a potentially important enzyme capable of regulating the activity of neuropeptides released in the respiratory mucosa. In order to confirm the existence of NEP in the human respiratory muco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f76ffaf12455f71ccbf42f0d2fcb88e
https://doi.org/10.1165/ajrcmb/9.5.557
https://doi.org/10.1165/ajrcmb/9.5.557
Publikováno v:
Journal of Allergy and Clinical Immunology. 89:1144-1150
To examine the localization of histamine H 1 receptors (H 1 R) in human nasal mucosa, the autoradiographic distribution of H 1 R was studied in human nasal inferior turbinates. Cryostat sections were incubated with various concentration of [ 3 H]pyri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4752964f516ae64d1b0798d2f0b599f3
https://doi.org/10.1016/0091-6749(92)90298-g
https://doi.org/10.1016/0091-6749(92)90298-g
Autor:
Marco Merida, J. Mullol, R. D. Rieves, James H. Shelhamer, Michael A. Kaliner, James N. Baraniuk, Jens D Lundgren, J.H. Hausfeld
Publikováno v:
Neuropeptides. 21:231-238
The role of neuropeptides in the regulation of macromolecule secretion from human nasal mucosa is incompletely understood. Previous in vitro explant culture studies have demonstrated the effects of neuropeptides on lactoferrin release from serous cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481671e7427dfba474bdfd874468accd
https://doi.org/10.1016/0143-4179(92)90027-t
https://doi.org/10.1016/0143-4179(92)90027-t
Autor:
Joaquim Mullol, Marco Merida, Sharon Castellino, Julie Goff, James H. Shelhamer, Michael A. Kaliner, Jens D Lundgren, James N. Baraniuk
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 3:165-173
Neuropeptide Y (NPY), a potent vasoconstrictor peptide found in sympathetic neurons, was analyzed in human inferior turbinate nasal mucosal tissue. NPY content determined by radioimmunoassay was 3.13 +/- 0.79 pmol/g tissue (n = 6) in mucosa extracted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ecceb7967084d781e1c05194dd0ad0
https://doi.org/10.1165/ajrcmb/3.2.165
https://doi.org/10.1165/ajrcmb/3.2.165
Autor:
James N. Baraniuk, Jens D Lundgren, Marco Merida, David B. Peden, James H. Shelhamer, Alexander Gawin, Michael A. Kaliner, Haruko Mizoguchi
Publikováno v:
American Review of Respiratory Disease. 141:706-714
Bradykinin (BK) and lysyl-BK (lys-BK, kallidin) have been proposed as potentially important mediators of rhinorrhea. Possible mechanisms by which BK might contribute to rhinorrhea were investigated by several approaches. (1) The autoradiographic dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7184c5533e75bb0260533219848cbdc
https://doi.org/10.1164/ajrccm/141.3.706
https://doi.org/10.1164/ajrccm/141.3.706
Autor:
Michael A. Kaliner, Kimihiro Ohkubo, Marco Merida, Hidechika Okada, James N. Baraniuk, Jeffrey N. Hausfeld
Publikováno v:
The Journal of allergy and clinical immunology. 96(6 Pt 1)
Carboxypeptidases (CPs), such as carboxypeptidase N (CPN) (kininase I, E.C.3.4.17.3), may regulate peptide-mediated vasodilation and vascular permeability in respiratory mucosa by degrading proinflammatory peptides such as bradykinin, anaphylatoxins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01dd4a85769365eeb52ea754c52402c3
https://pubmed.ncbi.nlm.nih.gov/8543751
https://pubmed.ncbi.nlm.nih.gov/8543751
Autor:
Chul Hee Lee, Jeffrey N. Hausfeld, Michael A. Kaliner, Marco Merida, K. Ohkubo, James N. Baraniuk
Publikováno v:
American journal of respiratory cell and molecular biology. 11(2)
Angiotensin-converting enzyme (ACE; EC 3.4.15.1) may participate in respiratory inflammatory diseases by regulating levels of inflammatory peptides such as bradykinin. The presence of ACE in the human nasal mucosa and in nasal secretions was determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47eae788abf2f0695672c133818d6332
https://pubmed.ncbi.nlm.nih.gov/8049077
https://pubmed.ncbi.nlm.nih.gov/8049077
Autor:
Bruce Feldman, Marco Merida, Michiko Okayama, Jeffery N. Hausfeld, Joaquim Mullol, James N. Baraniuk, Michael A. Kaliner, James H. Shelhamer
Publikováno v:
American journal of respiratory cell and molecular biology. 8(2)
Muscarinic receptors play important roles in the regulation of glandular secretion and vasomotor tone in human nasal mucosa. M1, M2, and M3 muscarinic receptor subtypes were pharmacologically characterized in human inferior turbinates by receptor-bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9229ecffdce40ce540fa329c0d30162b
https://pubmed.ncbi.nlm.nih.gov/8427708
https://pubmed.ncbi.nlm.nih.gov/8427708
Autor:
Marco Merida, James N. Baraniuk, C. Logun, J.H. Hausfeld, James H. Shelhamer, Michael A. Kaliner, J. Mullol
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 73(5)
Mucus glycoproteins (MGP) are high-molecular-weight glycoconjugates that are released from submucosal glands and epithelial goblet cells in the respiratory tract. Muscarinic receptors have an important role in the regulation of human nasal glandular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c95231a5f6705f209e9f9229dd6b666
https://pubmed.ncbi.nlm.nih.gov/1474087
https://pubmed.ncbi.nlm.nih.gov/1474087