Synthesis of dicarba-cyclooctapeptide Somatostatin analogs by conventional and MW-assisted RCM: A study about the impact of the configuration at C α of selected amino acids

Autor: Alfonso Carotenuto, Anna Maria Papini, Diego Brancaccio, Giuseppina Sabatino, Samuele Stazzoni, Marco Chinol, Mauro Ginanneschi, Paolo Rovero, Marco Lumini, Alessandro Pratesi, Ettore Novellino

Publikováno v: Chemical engineering and processing
122 (2017): 365–372. doi:10.1016/j.cep.2017.02.005
info:cnr-pdr/source/autori:Pratesi A.; Stazzoni S.; Lumini M.; Sabatino G.; Carotenuto A.; Brancaccio D.; Novellino E.; Chinol M.; Rovero P.; Ginanneschi M.; Papini A.M./titolo:Synthesis of dicarba-cyclooctapeptide Somatostatin analogs by conventional and MW-assisted RCM: A study about the impact of the configuration at C? of selected amino acids/doi:10.1016%2Fj.cep.2017.02.005/rivista:Chemical engineering and processing (Print)/anno:2017/pagina_da:365/pagina_a:372/intervallo_pagine:365–372/volume:122

This work describes the synthesis of thirteen cyclooctapeptides dicarba-analogues of Somatostatin, containing l- or d-allylglycine (Agl) residues at the termini of the peptide chain, through on resin Ring Closing Metathesis (RCM) of the linear octape

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7379a30f423e837c8a6c3d550c178220
https://doi.org/10.1016/j.cep.2017.02.005

Straightforward Synthesis of α-Substituted Prolines by Cross-Metathesis

Autor: Marco Lumini, Federica Pisaneschi, Franca M. Cordero, Alberto Brandi

Publikováno v: European Journal of Organic Chemistry. 2008:2817-2824

The synthesis of several α-substituted N-Boc-protected prolines has been achieved by cross metathesis (CM) of N-Boc-allylproline 5 with terminal long chain alkenes and alkenes bearing hydroxy, silyloxy, ester, and O-acetylglucosamido groups. The CM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ecce49dd0261b3e1bcbe3003e02efa68
https://doi.org/10.1002/ejoc.200800044

ChemInform Abstract: Straightforward Synthesis of α-Substituted Prolines by Cross-Metathesis

Autor: Federica Pisaneschi, Marco Lumini, Franca M. Cordero, Alberto Brandi

Publikováno v: ChemInform. 39

The synthesis of several α-substituted N-Boc-protected prolines has been achieved by cross metathesis (CM) of N-Boc-allylproline 5 with terminal long chain alkenes and alkenes bearing hydroxy, silyloxy, ester, and O-acetylglucosamido groups. The CM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62ad1980346f83ada569eca42c43b85a
https://doi.org/10.1002/chin.200840183