Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Marco Lepore"'
Autor:
Anna-Lisa Lanz, Giulia Masi, Nicla Porciello, André Cohnen, Deborah Cipria, Dheeraj Prakaash, Štefan Bálint, Roberto Raggiaschi, Donatella Galgano, David K. Cole, Marco Lepore, Omer Dushek, Michael L. Dustin, Mark S.P. Sansom, Antreas C. Kalli, Oreste Acuto
Publikováno v:
Cell Reports, Vol 36, Iss 6, Pp 109531- (2021)
Externí odkaz:
https://doaj.org/article/a6cb432e0b0a4011bea51b73db0ce5dd
Autor:
Frank Camacho, María E Sarmiento, Fatima Reyes, Louise Kim, Jim Huggett, Marco Lepore, Oscar Otero, Martine Gilleron, Germain Puzo, Mohd Nor Norazmi, Graham Rook, Lucia Mori, Gennaro De Libero, Armando Acosta
Publikováno v:
International Journal of Mycobacteriology, Vol 5, Iss 2, Pp 120-127 (2016)
Objective/background: The development of new tools capable of targeting Mycobacterium tuberculosis (Mtb)-infected cells have potential applications in diagnosis, treatment, and prevention of tuberculosis. In Mtb-infected cells, CD1b molecules present
Externí odkaz:
https://doaj.org/article/99975624cc9f4975a1db3f4d7cbb2f23
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The definition “unconventional T cells” identifies T lymphocytes that recognize non-peptide antigens presented by monomorphic antigen-presenting molecules. Two cell populations recognize lipid antigens and small metabolites presented by CD1 and M
Externí odkaz:
https://doaj.org/article/4dca8bcddeb24434b153dba3a94d0288
Autor:
Marco Lepore, Artem Kalinichenko, Salvatore Calogero, Pavanish Kumar, Bhairav Paleja, Mathias Schmaler, Vipin Narang, Francesca Zolezzi, Michael Poidinger, Lucia Mori, Gennaro De Libero
Publikováno v:
eLife, Vol 6 (2017)
Externí odkaz:
https://doaj.org/article/3374ccea4ada4b3e9c91ab2953cb90b9
Autor:
Marco Lepore, Artem Kalinichenko, Salvatore Calogero, Pavanish Kumar, Bhairav Paleja, Mathias Schmaler, Vipin Narang, Francesca Zolezzi, Michael Poidinger, Lucia Mori, Gennaro De Libero
Publikováno v:
eLife, Vol 6 (2017)
MHC class I-related molecule MR1 presents riboflavin- and folate-related metabolites to mucosal-associated invariant T cells, but it is unknown whether MR1 can present alternative antigens to other T cell lineages. In healthy individuals we identifie
Externí odkaz:
https://doaj.org/article/ff20e9a13f644a6d899b550d0f9e97dd
Autor:
Alessandro Vacchini, Qinmei Yang, Andrew Chancellor, Julian Spagnuolo, Daniel Joss, Ove Øyås, Aisha Beshirova, Corinne De Gregorio, Michael Pfeffer, Jörg Stelling, Daniel Häussinger, Marco Lepore, Lucia Mori, Gennaro De Libero
SummaryMR1T lymphocytes are a recently identified population of T cells that recognize unknown self-antigens presented by the non-polymorphic MHC-I-related molecule, MR1. MR1T cells can kill tumor cells and modulate the functions of other immune cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::849c28716effa236a9d7ad52e4500711
https://doi.org/10.1101/2022.08.26.505411
https://doi.org/10.1101/2022.08.26.505411
Publikováno v:
Mol Immunol
The monomorphic MHC-class I-like molecule, MR1, presents small metabolites to T cells. MR1 is the restriction element for microbe-reactive mucosal-associated invariant T (MAIT) cells. MAIT cells have limited TCR usage, including a semi-invariant TCR
Autor:
Said Jongo, Jean-Pierre Dangy, Daniela Di Blasi, Stephen L. Hoffman, Marco Lepore, Claudia Daubenberger, B. Kim Lee Sim, Salim Abdulla, Tobias Rutishauser, Kamaka Ramadhani, Marcel Tanner, Gennaro De Libero
Publikováno v:
The Journal of Immunology. 204:180-191
Our understanding of the human immune response to malaria remains incomplete. Clinical trials using whole-sporozoite-based vaccination approaches such as the Sanaria PfSPZ Vaccine, followed by controlled human malaria infection (CHMI) to assess vacci
Publikováno v:
Bio-Protocol, Vol 5, Iss 11 (2015)
Autoreactive T cells restricted to CD1 molecules and specific for endogenous lipids are abundant in human blood (de Jong et al., 2010; de Lalla et al., 2011). A few self-lipid molecules recognized by diverse individual T cell clones and accumulated w
Externí odkaz:
https://doaj.org/article/93fe70d9f7c04152aadaf6ab696dfcc4
Autor:
Nicla Porciello, Dheeraj Prakaash, Michael L. Dustin, Antreas C. Kalli, Oreste Acuto, Roberto Raggiaschi, Marco Lepore, Omer Dushek, Giulia Masi, Andre Cohnen, Deborah Cipria, Mark S.P. Sansom, Anna-Lisa Lanz, David K. Cole, Donatella Galgano, Štefan Bálint
Publikováno v:
Cell Reports, Vol 36, Iss 6, Pp 109531-(2021)
Cell Reports
Cell Reports, Vol 36, Iss 2, Pp 109375-(2021)
Cell Reports
Cell Reports, Vol 36, Iss 2, Pp 109375-(2021)
Summary The mechanism of T cell antigen receptor (TCR-CD3) signaling remains elusive. Here, we identify mutations in the transmembrane region of TCRβ or CD3ζ that augment peptide T cell antigen receptor (pMHC)-induced signaling not explicable by en