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pro vyhledávání: '"Marco Jochem"'
Post-transcriptional gene regulation is accomplished by the interplay of the transcriptome with RNA-binding proteins, which occurs in a dynamic manner in response to altered cellular conditions. Recording the combined occupancy of all proteins bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::888783be2b18ab875beb9b1fd25e5d7a
https://doi.org/10.1101/2022.07.28.501819
https://doi.org/10.1101/2022.07.28.501819
Autor:
Lucy C. Robinson, Pavel Ivanov, Marco Jochem, Rini Ravindran, Hendrik Welsch, Helena M. Schnell, Kelly Tatchell, Yagmur Micoogullari, Claire L. Riggs, Paul A. Anderson, John Hanna
Publikováno v:
FEBS J
The compartmentalization of cellular function is achieved largely through the existence of membrane-bound organelles. However, recent work suggests a novel mechanism of compartmentalization mediated by membraneless structures that have liquid droplet
Autor:
Jakob Trendel, Milan Aleksić, Matilde Bertolini, Marco Jochem, Günter Kramer, Stefan Pfeffer, Bernd Bukau, Jeroen Krijgsveld
SummaryRibosomes are among the most abundant and complex machineries in the cell, however, the turnover of their subunits remains poorly understood. Here, we apply proteomic flux and cryo-electron microscopy analyses to interrogate the ribosome life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c24c1395755404520bd1b903ff68197
https://doi.org/10.1101/2022.05.13.491786
https://doi.org/10.1101/2022.05.13.491786
Publikováno v:
FEBS Lett
In the unfolded protein response (UPR), Ire1 activates Hac1 to coordinate the transcription of hundreds of genes to mitigate ER stress. Recent work in Caenorhabditis elegans suggests that oxidative stress inhibits this canonical Ire1 signalling pathw
Autor:
Jessie Ang, Marta Isasa, John Hanna, Steven P. Gygi, Meera K. Bhanu, Marco Jochem, Helena M. Schnell, Lukas Ende, Yagmur Micoogullari, Angel Guerra-Moreno
Publikováno v:
Molecular and cellular biology. 39(10)
The abundance of cell surface glucose transporters must be precisely regulated to ensure optimal growth under constantly changing environmental conditions. We recently conducted a proteomic analysis of the cellular response to trivalent arsenic, a ub