Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marco I. Gonzalez"'
Autor:
Allison E. Tipton, Yasmin Cruz Del Angel, Kathryn Hixson, Jessica Carlsen, Dana Strode, Nicolas Busquet, Michael H. Mesches, Marco I. Gonzalez, Eleonora Napoli, Shelley J. Russek, Amy R. Brooks‐Kayal
Publikováno v:
Ann Neurol
Annals of neurology, vol 94, iss 1
Annals of neurology, vol 94, iss 1
ObjectiveTemporal lobe epilepsy (TLE) is a progressive disorder mediated by pathological changes in molecular cascades and hippocampal neural circuit remodeling that results in spontaneous seizures and cognitive dysfunction. Targeting these cascades
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b313d9fbbfa42a4052456591a1d346fa
https://europepmc.org/articles/PMC10313781/
https://europepmc.org/articles/PMC10313781/
Autor:
Marco I Gonzalez
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 7 (2013)
The term epileptogenesis refers to a dynamic alteration in neuronal excitability that promotes the appearance of spontaneous seizures. Temporal lobe epilepsy (TLE), the most common type of acquired epilepsy, often develops after an insult to the brai
Externí odkaz:
https://doaj.org/article/cf264db9d7a24cb3ba169ead03916d6a
Autor:
Philip M. Lam, Marco I. González
Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 141-151 (2019)
Epilepsy is a brain disorder characterized by a predisposition to suffer epileptic seizures. Acquired epilepsy might be the result of brain insults like head trauma, stroke, brain infection, or status epilepticus (SE) when one of these triggering inj
Externí odkaz:
https://doaj.org/article/c4bbc7852a064dfd9da97e275d40d98a
Autor:
Md. Mahiuddin Ahmed, Andrew J. Carrel, Yasmin Cruz Del Angel, Jessica Carlsen, Ajay X. Thomas, Marco I. González, Katheleen J. Gardiner, Amy Brooks-Kayal
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Epilepsy is characterized by recurrent, spontaneous seizures and is a major contributor to the global burden of neurological disease. Although epilepsy can result from a variety of brain insults, in many cases the cause is unknown and, in a significa
Externí odkaz:
https://doaj.org/article/2dd34466bf12465bb4794d3c67504428
Publikováno v:
Neurobiology of Disease, Vol 102, Iss , Pp 1-10 (2017)
In this study, we used the pilocarpine model of epilepsy to evaluate the involvement of calpain dysregulation on epileptogenesis. Detection of spectrin breakdown products (SBDPs, a hallmark of calpain activation) after induction of pilocarpine-induce
Externí odkaz:
https://doaj.org/article/b8fc0b0905d0401d8add062c216375d7
Autor:
Marco I. González, Heidi L. Grabenstatter, Christian A. Cea-Del Rio, Yasmin Cruz Del Angel, Jessica Carlsen, Rick P. Laoprasert, Andrew M. White, Molly M. Huntsman, Amy Brooks-Kayal
Publikováno v:
Neurobiology of Disease, Vol 77, Iss , Pp 246-256 (2015)
In this study, we analyzed the impact that spontaneous seizures might have on the plasma membrane expression, composition and function of GABAA receptors (GABAARs). For this, the tissue of chronically epileptic rats was collected within 3 h of seizur
Externí odkaz:
https://doaj.org/article/c049b342e2c54635bd33858d0df35b9f