Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Marco Fuenzalida"'
Autor:
Carla Álvarez-Ferradas, Mario Wellmann, Koyam Morales, Marco Fuenzalida, Waldo Cerpa, Nibaldo C. Inestrosa, Christian Bonansco
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Synapse unsilencing is an essential mechanism for experience-dependent plasticity. Here, we showed that the application of the ligand Wnt-5a converts glutamatergic silent synapses into functional ones by increasing both α-amino-3-hydroxy-5-methyl-4-
Externí odkaz:
https://doaj.org/article/1082d02777fb4dc8a7a9cef7fab67bd7
Autor:
Rossy Olivares-Barraza, José Luis Marcos, Jonathan Martínez-Pinto, Marco Fuenzalida, Javier A. Bravo, Katia Gysling, Ramón Sotomayor-Zárate
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Obesity is a pandemic associated with lifestyles changes. These include excess intake of obesogenic foods and decreased physical activity. Brain areas, like the lateral hypothalamus (LH), ventral tegmental area (VTA), and nucleus accumbens (NAcc) hav
Externí odkaz:
https://doaj.org/article/7dd7183860134192baf1af65265e2596
Autor:
Francisca García-Rojas, Carolina Flores-Muñoz, Odra Santander, Pamela Solis, Agustín D. Martínez, Álvaro O. Ardiles, Marco Fuenzalida
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 887 (2023)
Pannexin-1 (Panx1) hemichannel is a non-selective transmembrane channel that may play important roles in intercellular signaling by allowing the permeation of ions and metabolites, such as ATP. Although recent evidence shows that the Panx1 hemichanne
Externí odkaz:
https://doaj.org/article/8ecaa2306d264fb7b9d02fe0f0e00e12
Autor:
Carolina Flores-Muñoz, Francisca García-Rojas, Miguel A. Pérez, Odra Santander, Elena Mery, Stefany Ordenes, Javiera Illanes-González, Daniela López-Espíndola, Arlek M. González-Jamett, Marco Fuenzalida, Agustín D. Martínez, Álvaro O. Ardiles
Publikováno v:
Cells, Vol 11, Iss 22, p 3646 (2022)
Enhanced activity and overexpression of Pannexin 1 (Panx1) channels contribute to neuronal pathologies such as epilepsy and Alzheimer’s disease (AD). The Panx1 channel ablation alters the hippocampus’s glutamatergic neurotransmission, synaptic pl
Externí odkaz:
https://doaj.org/article/b2ec816e17904dd487b66dbd7a5d8337
Autor:
Viviana Pérez, Francisca Bermedo-Garcia, Diego Zelada, Felipe A. Court, Miguel Ángel Pérez, Marco Fuenzalida, Johanna Ábrigo, Claudio Cabello-Verrugio, Guillermo Moya-Alvarado, Juan Carlos Tapia, Vicente Valenzuela, Claudio Hetz, Francisca C. Bronfman, Juan Pablo Henríquez
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract The coordinated movement of organisms relies on efficient nerve-muscle communication at the neuromuscular junction. After peripheral nerve injury or neurodegeneration, motor neurons and Schwann cells increase the expression of the p75NTR pan
Externí odkaz:
https://doaj.org/article/0b9402c28e954f8a8bcf73f82d244d49
Publikováno v:
Neurobiology of Disease, Vol 146, Iss , Pp 105132- (2020)
Epilepsy is characterized by a progressive predisposition to suffer seizures due to neuronal hyperexcitability, and one of its most common co-morbidities is cognitive decline. In animal models of chronic epilepsy, such as kindling, electrically induc
Externí odkaz:
https://doaj.org/article/e93eb9d0d6e848cab024a027bb25167e
Autor:
Miguel Ángel Pérez, Camila Morales, Odra Santander, Francisca García, Isabel Gómez, Valentín Peñaloza-Sancho, Pablo Fuentealba, Alexies Dagnino-Subiabre, Pablo R. Moya, Marco Fuenzalida
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Schizophrenia (SZ) is associated with changes in the structure and function of several brain areas. Several findings suggest that these impairments are related to a dysfunction in γ-aminobutyric acid (GABA) neurotransmission in brain areas such as t
Externí odkaz:
https://doaj.org/article/239005d8197d42ec83e796f39b6f1259
Autor:
Marco Fuenzalida, Claudia Espinoza, Miguel Ángel Pérez, Cheril Tapia-Rojas, Loreto Cuitino, Enrique Brandan, Nibaldo C. Inestrosa
Publikováno v:
Neurobiology of Disease, Vol 86, Iss , Pp 109-120 (2016)
The dystrophin-associated glycoprotein complex (DGC) that connects the cytoskeleton, plasma membrane and the extracellular matrix has been related to the maintenance and stabilization of channels and synaptic receptors, which are both essential for s
Externí odkaz:
https://doaj.org/article/dfa54dda5c394768b07b7a58efa3bbab
Autor:
Gertrudis Perea, Ricardo Gómez, Sara Mederos, Ana Covelo, Jesús J Ballesteros, Laura Schlosser, Alicia Hernández-Vivanco, Mario Martín-Fernández, Ruth Quintana, Abdelrahman Rayan, Adolfo Díez, Marco Fuenzalida, Amit Agarwal, Dwight E Bergles, Bernhard Bettler, Denise Manahan-Vaughan, Eduardo D Martín, Frank Kirchhoff, Alfonso Araque
Publikováno v:
eLife, Vol 5 (2016)
Interneurons are critical for proper neural network function and can activate Ca2+ signaling in astrocytes. However, the impact of the interneuron-astrocyte signaling into neuronal network operation remains unknown. Using the simplest hippocampal Ast
Externí odkaz:
https://doaj.org/article/702faf8590a54ed9848dcd7914edf025
Autor:
Christian Bonansco, Marco Fuenzalida
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Synaptic plasticity is the capacity generated by experience to modify the neural function and, thereby, adapt our behaviour. Long-term plasticity of glutamatergic and GABAergic transmission occurs in a concerted manner, finely adjusting the excitator
Externí odkaz:
https://doaj.org/article/3d5913026fa7464f8ebb880cc18d0509