A Human Ovarian Tumor & Liver Organ-on-Chip for Simultaneous and More Predictive Toxo-Efficacy Assays

Autor: Arianna Fedi, Chiara Vitale, Marco Fato, Silvia Scaglione

Publikováno v: Bioengineering, Vol 10, Iss 2, p 270 (2023)

In oncology, the poor success rate of clinical trials is becoming increasingly evident due to the weak predictability of preclinical assays, which either do not recapitulate the complexity of human tissues (i.e., in vitro tests) or reveal species-spe

Externí odkaz: https://doaj.org/article/01034a6870f44ec288854cae28cfb7c3

3D Perfusable Hydrogel Recapitulating the Cancer Dynamic Environment to in Vitro Investigate Metastatic Colonization

Autor: Chiara Vitale, Arianna Fedi, Alessandra Marrella, Gabriele Varani, Marco Fato, Silvia Scaglione

Publikováno v: Polymers, Vol 12, Iss 11, p 2467 (2020)

Metastasis is a dynamic process involving the dissemination of circulating tumor cells (CTCs) through blood flow to distant tissues within the body. Nevertheless, the development of an in vitro platform that dissects the crucial steps of metastatic c

Externí odkaz: https://doaj.org/article/3de7f261f3fa4ef7bf9bf9e0c9b74e80

High blood flow shear stress values are associated with circulating tumor cells cluster disaggregation in a multi-channel microfluidic device

Autor: Arianna Fedi, Nicola Aceto, Gabriele Varani, Giuseppe Firpo, Ivan Vaccari, Silvia Scaglione, Alessandra Marrella, Patrizia Guida, Marco Fato

Publikováno v: PLoS ONE, 16 (1)
PloS one 16 (2021). doi:10.1371/journal.pone.0245536
info:cnr-pdr/source/autori:Marrella A.; Fedi A.; Varani G.; Vaccari I.; Fato M.; Firpo G.; Guida P.; Aceto N.; Scaglione S./titolo:High blood flow shear stress values are associated with circulating tumor cells cluster disaggregation in a multi-channel microfluidic device/doi:10.1371%2Fjournal.pone.0245536/rivista:PloS one/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:16
PLOS ONE
PLoS ONE, Vol 16, Iss 1, p e0245536 (2021)
PLoS ONE

Metastasis represents a dynamic succession of events involving tumor cells which disseminate through the organism via the bloodstream. Circulating tumor cells (CTCs) can flow the bloodstream as single cells or as multicellular aggregates (clusters),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8579b8cb51db41a5612f6b380e849352
https://hdl.handle.net/11567/1036853

Long-range phase synchronization of high-frequency oscillations in human cortex

Autor: Lino Nobili, Satu Palva, Benedetta Toselli, Vladislav Myrov, Jonni Hirvonen, Gabriele Arnulfo, Alexander Zhigalov, Marco Fato, Jaakko Matias Palva, Sheng H. Wang, Francesco Cardinale, Annalisa Rubino

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications

Inter-areal synchronization of neuronal oscillations at frequencies below ~100 Hz is a pervasive feature of neuronal activity and is thought to regulate communication in neuronal circuits. In contrast, faster activities and oscillations have been con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e51524ed52648a39d1c2818b925ce27
https://hdl.handle.net/11567/1036844

3D Perfusable Hydrogel Recapitulating the Cancer Dynamic Environment to in Vitro Investigate Metastatic Colonization

Autor: Marco Fato, Chiara Vitale, Gabriele Varani, Silvia Scaglione, Arianna Fedi, Alessandra Marrella

Publikováno v: Polymers
Volume 12
Issue 11
Polymers, Vol 12, Iss 2467, p 2467 (2020)

Metastasis is a dynamic process involving the dissemination of circulating tumor cells (CTCs) through blood flow to distant tissues within the body. Nevertheless, the development of an in vitro platform that dissects the crucial steps of metastatic c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1179f3d527e3e40392a9be9e4c0e0b0c