Reconstruction of the Swine Pulmonary Artery Using a Graft Engineered With Syngeneic Cardiac Pericytes

Autor: Valeria Vincenza Alvino, Anita C. Thomas, Mohamed T. Ghorbel, Filippo Rapetto, Srinivas A. Narayan, Michael Kilcooley, Dominga Iacobazzi, Michele Carrabba, Marco Fagnano, William Cathery, Elisa Avolio, Massimo Caputo, Paolo Madeddu

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)

The neonatal heart represents an attractive source of regenerative cells. Here, we report the results of a randomized, controlled, investigator-blinded preclinical study, which assessed the safety and effectiveness of a matrix graft cellularized with

Externí odkaz: https://doaj.org/article/2389eec8c4f148f888db784ea00ac5a8

In Vitro and In Vivo Preclinical Testing of Pericyte‐Engineered Grafts for the Correction of Congenital Heart Defects

Autor: Valeria Vincenza Alvino, Michael Kilcooley, Anita C. Thomas, Michele Carrabba, Marco Fagnano, William Cathery, Elisa Avolio, Dominga Iacobazzi, Mohamed Ghorbel, Massimo Caputo, Paolo Madeddu

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 4 (2020)

Background We have previously reported the possibility of using pericytes from leftovers of palliative surgery of congenital heart disease to engineer clinically certified prosthetic grafts. Methods and Results Here, we assessed the feasibility of us

Externí odkaz: https://doaj.org/article/061936df9811481ba567e5290313ed83

Reconstruction of the Swine Pulmonary Artery Using a Graft Engineered With Syngeneic Cardiac Pericytes

Autor: Srinivas A. Narayan, Michele Carrabba, Marco Fagnano, Anita C Thomas, Michael Kilcooley, Filippo Rapetto, Paolo Madeddu, Elisa Avolio, Mohamed T. Ghorbel, Dominga Iacobazzi, William Cathery, Valeria Vincenza Alvino, Massimo Caputo

Publikováno v: Frontiers in Bioengineering and Biotechnology
Alvino, V V, Thomas, A C, Ghorbel, M, Rapetto, F, Narayan, S, Kilcooley, M, Iacobazzi, D, Carrabba, M, Fagnano, M, Cathery, W R, Avolio, E, Caputo, M & Madeddu, P R 2021, ' Reconstruction of the swine pulmonary artery using a graft engineered with syngeneic cardiac pericytes ', Frontiers in Bioengineering and Biotechnology, vol. 9, 715717 . https://doi.org/10.3389/fbioe.2021.715717
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)

The neonatal heart represents an attractive source of regenerative cells. Here, we report the results of a randomized, controlled, investigator-blinded preclinical study, which assessed the safety and effectiveness of a matrix graft cellularized with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab90827b9d2ae7dc18741e63f529d2a
http://europepmc.org/articles/PMC8459923

Human saphenous vein provides a unique source of anti-calcific pericytes for prosthetic cardiac valve engineering

Autor: Eva Jover, Marco Fagnano, William Cathery Meng, Sadie Slater, Emanuela Pisanu, Yue Gu, Elisa Avolio, Domenico Bruno, Daniel Baz-Lopez, Ashton Faulkner, Michele Carrabba, Gianni Angelini, Paolo Madeddu

AimsTissue engineering seeks to improve the longevity of prosthetic heart valves, but the cell source of choice has yet to be determined. This study aimed to establish a mechanistic rationale supporting the suitability of human adventitial pericytes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f76b03e34bb1dc0ce245ff6c200df29
https://doi.org/10.1101/2020.07.14.202846

Cell Sources for Tissue Engineering Strategies to Treat Calcific Valve Disease

Autor: Gianni D Angelini, Paolo Madeddu, Eva Jover, Marco Fagnano

Publikováno v: Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Fagnano, M, Jover Garcia, E, Madeddu, P & Angelini, G 2018, ' Cell Sources for Tissue Engineering Strategies to Treat Calcific Valve Disease ', Frontiers in Cardiovascular Medicine, vol. 5, 155 . https://doi.org/10.3389/fcvm.2018.00155

Cardiovascular calcification is an independent risk factor and an established predictor of adverse cardiovascular events. Despite concomitant factors leading to atherosclerosis and heart valve disease (VHD), the latter has been identified as an indep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13abf89715f11aa614fdde6bcecc0bb2
http://europepmc.org/articles/PMC6232262