Výsledky vyhledávání - "Marco Elegante"

Zebrafish models to study drug abuse-related phenotypes

Autor: Siddharth Gaikwad, Marco Elegante, Allan V. Kalueff, Eli Utterback, David Tien, Keith Wong, Nadine Wu, Evan J. Kyzar, Valerie Piet, Jonathan Cachat, Adam Stewart, Peter C. Hart

Publikováno v: revneuro. 22:95-105

Mounting evidence implicates the zebrafish (Danio rerio) as a promising model species for reward and addiction research. Modeling drug abuse-related behavior in both adult and larval zebrafish produced a wealth of clinically translatable data, also d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da19c193f112c44cd3c89eda5c71d2d
https://doi.org/10.1515/rns.2011.011

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Characterization of behavioral and endocrine effects of LSD on zebrafish

Autor: Keith Wong, Kyung Min Chung, Adam Stewart, Eli Utterback, Marco Elegante, John DiLeo, Nadine Wu, Julia Tan, Christopher Suciu, Thomas Gilder, Jonathan Cachat, Allan V. Kalueff, Siddharth Gaikwad, Salem Elkhayat, Leah Grossman

Publikováno v: Behavioural Brain Research. 214:277-284

Lysergic acid diethylamide (LSD) is a potent hallucinogenic drug that strongly affects animal and human behavior. Although adult zebrafish (Danio rerio) are emerging as a promising neurobehavioral model, the effects of LSD on zebrafish have not been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f4691ae43460b8ce345cba048adebb
https://doi.org/10.1016/j.bbr.2010.05.039

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Neurosteroid vitamin D system as a nontraditional drug target in neuropsychopharmacology

Autor: Tom Gilder, Marco Elegante, Keith Wong, Anna Minasyan, Jonathan Cachat, Adam Stewart, Allan V. Kalueff, Pentti Tuohimaa, Nadine Wu, Sopan Mohnot

Publikováno v: Behavioural Pharmacology. 21:420-426

Vitamin D is becoming increasingly recognized as a nontraditional drug target for different brain pathologies. Although widely known for their role in calcium metabolism, vitamin D and its receptor have been linked to several brain disorders, includi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ddc1301fdfc82234d006a709466af9
https://doi.org/10.1097/fbp.0b013e32833c850f

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The effects of chronic social defeat stress on mouse self-grooming behavior and its patterning

Publikováno v: Behavioural Brain Research. 208:553-559

Stress induced by social defeat is a strong modifier of animal anxiety and depression-like phenotypes. Self-grooming is a common rodent behavior, and has an ordered cephalo-caudal progression from licking of the paws to head, body, genitals and tail.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1fbd5e879178ce2254f10aae327042
https://doi.org/10.1016/j.bbr.2009.12.041

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Measuring behavioral and endocrine responses to novelty stress in adult zebrafish

Publikováno v: Nature protocols. 5(11)

Several behavioral assays are currently used for high-throughput neurophenotyping and screening of genetic mutations and psychotropic drugs in zebrafish (Danio rerio). In this protocol, we describe a battery of two assays to characterize anxiety-rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f3ed0ad59d1b317ad50dc4ae2e0bd7
https://pubmed.ncbi.nlm.nih.gov/21030954

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Phenotyping of Zebrafish Homebase Behaviors in Novelty-Based Tests

Publikováno v: Neuromethods ISBN: 9781607619529

Various novelty-based assays used to quantify zebrafish (Danio rerio) behavior show a striking similarity to behavioral responses in rodents. Exposed to the open field test, zebrafish establish overt homebases demonstrating clear preference for a par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::256519d75c86597a858129e6599148cd
https://doi.org/10.1007/978-1-60761-953-6_12

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Assessing the Maximum Predictive Validity for Neuropharmacological Anxiety Screening Assays Using Zebrafish

Autor: Amanda Linker, Siddharth Gaikwad, Jason E. Warnick, Allan V. Kalueff, Adam Stewart, Marco Elegante, Jonathan Cachat

Publikováno v: Neuromethods ISBN: 9781607619529

The development of reliable pharmacological screening assays is an important task. However, it is based upon the ability of animal models, such as the zebrafish, to demonstrate predictive validity for a specific set of drug classes. A popular assay u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::857ce8d468444d69741e03ef382e5d32
https://doi.org/10.1007/978-1-60761-953-6_15

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Measuring Endocrine (Cortisol) Responses of Zebrafish to Stress

Autor: David Tien, Allan V. Kalueff, Esther Beeson, Marco Elegante, Sopan Mohnot, Whitlee A.M. Haymore, Autumn L. Laffoon, Peter R. Canavello, Chelsea Grimes, Brett Bartels, Salem Elkhayat, Peter C. Hart, Hakima Amri, Jonathan Cachat

Publikováno v: Neuromethods ISBN: 9781607619529

The zebrafish (Danio rerio) is rapidly becoming a popular model species in stress and neuroscience research. Their behavior, robustly affected by environmental and pharmacological manipulations, can be paralleled by physiological (endocrine) analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb82b8d1137dcc25c0fb62f0ea538602
https://doi.org/10.1007/978-1-60761-953-6_11

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Modeling Stress and Anxiety in Zebrafish

Autor: Whitlee A.M. Haymore, Anna K. Tien, Autumn L. Laffoon, Salem Elkhayat, Keith Wong, Jonathan Cachat, Sopan Mohnot, Siddharth Gaikwad, Esther Beeson, David Tien, Adam Stewart, Peter C. Hart, Marco Elegante, Brett Bartels, Allan V. Kalueff, Peter R. Canavello

Publikováno v: Neuromethods ISBN: 9781607619215

While zebrafish (Danio rerio) are widely utilized as a model species for neuroscience research, they also possess several qualities that make them particularly useful for studying stress and anxiety-related behaviors. Zebrafish neuroendocrine respons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::919add1d82394d5ff3ed067fbcb4fa3c
https://doi.org/10.1007/978-1-60761-922-2_3

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