Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marco Carvalho Oliveira"'
Autor:
Mania Ackermann, Fawaz Saleh, Shifaa M. Abdin, Anna Rafiei Hashtchin, Ingrid Gensch, Julia Golgath, Marco Carvalho Oliveira, Ariane H. H. Nguyen, Svenja Gaedcke, Arno Fenske, Mi-Sun Jang, Adan C. Jirmo, Markus Abeln, Gesine Hansen, Nico Lachmann
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background There is a significant demand for intermediate-scale bioreactors in academic and industrial institutions to produce cells for various applications in drug screening and/or cell therapy. However, the application of these bioreactor
Externí odkaz:
https://doaj.org/article/a386a9eed5a141dcb1f49f98b94c1d5f
Autor:
Gesine Hansen, Axel Schambach, Christine S Falk, Arnold Kloos, Michael Morgan, Shifaa M. Abdin, Daniela Paasch, Nico Lachmann, Marco Carvalho Oliveira, Mi-Sun Jang, Mania Ackermann, Andriana Stamopoulou, Philipp J Mroch, Constantin S von Kaisenberg, Michael Heuser, Thomas Moritz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Background Macrophages have recently become attractive therapeutics in cancer immunotherapy. The potential of macrophages to infiltrate and influence solid malignancies makes them promising targets for the chimeric antigen receptor (CAR) technology t
Externí odkaz:
https://doaj.org/article/95887552adbe4426b971a8b340ad3b4a
Autor:
Emilio Valdivia, Marina Bertolin, Claudia Breda, Marco Carvalho Oliveira, Anna Katharina Salz, Nicola Hofmann, Martin Börgel, Rainer Blasczyk, Stefano Ferrari, Constanca Figueiredo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Limbal stem cell (LSC) transplantation is the only efficient treatment for patients affected by LSC deficiency (LSCD). Allogeneic LSC transplantation is one of the most successful alternative for patients with bilateral LSCD. Nevertheless, the high v
Externí odkaz:
https://doaj.org/article/855923347e4f4f2fa2749f850be3fb65
Autor:
Constanca Figueiredo, Reinhard Schwinzer, Yuliia Yuzefovych, Murielle Verboom, Rainer Blasczyk, Emilio Valdivia, Heiner Niemann, Björn Petersen, Marco Carvalho Oliveira, Hendrik Sake, Olena Pogozhykh, Jochen Seissler
Publikováno v:
Journal of Cellular and Molecular Medicine
Xenotransplantation of pancreatic islets offers a promising alternative to overcome the shortage of allogeneic donors. Despite significant advances, either immune rejection or oxygen supply in immune protected encapsulated islets remains major bottle
Autor:
Mania Ackermann, Anna Rafiei Hashtchin, Felix Manstein, Marco Carvalho Oliveira, Henning Kempf, Robert Zweigerdt, Nico Lachmann
Publikováno v:
Nat Protoc
Nature Protocols
Nature Protocols
Macrophages derived from human induced pluripotent stem cells (iPSC) have the potential to enable the development of cell-based therapies for numerous disease conditions. We here provide a detailed protocol for the mass-production of iPSC-derived mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c14f4d1e47f41537e96688f0c29e02
https://europepmc.org/articles/PMC7612500/
https://europepmc.org/articles/PMC7612500/
Autor:
Klaus Höffler, Olena Pogozhykh, Gregor Warnecke, Constanca Figueiredo, Mark P. Kühnel, Marco Carvalho Oliveira, Rainer Blasczyk, Bettina Wiegmann, Axel Haverich, Yuliia Yuzefovych, Chen Chen-Wacker, Danny Jonigk, Wiebke Sommer, Zhu Jin, Katharina Jansson
Publikováno v:
Human Gene Therapy. 30:485-496
Disparities at the major histocompatibility complex (MHC) antigens and associated minor antigens trigger harmful immune responses, leading to graft rejection after transplantation. We showed that MHC-silenced cells and tissues are efficiently protect
Publikováno v:
International journal of immunogeneticsREFERENCES. 48(2)
Xenotransplantation may become the highly desired solution to close the gap between the availability of donated organs and number of patients on the waiting list. In recent years, enormous progress has been made in the development of genetically engi
Autor:
E. Tavares-Silva, Mafalda Laranjo, Maria Filomena Botelho, Rui Caetano-Oliveira, Paulo Rodrigues Santos, Marco Carvalho Oliveira, Denise Gonçalves Priolli, Rosa H A M Henriques de Gouveia, Lina Carvalho, Débora Basílio Queirós, Ana M. Abrantes, João Casalta-Lopes, Marcos António Gomes, Salomé Pires, José Guilherme Tralhão
Publikováno v:
Pathophysiology. 25:89-99
Colorectal cancer (CRC) is the second most frequent and fatal cancer in Western countries. Understanding its biology with different incidence along the colon and rectum, genetic profile and how these factors contribute to local/distant progression, h
Autor:
Florian W. R. Vondran, A. Akhdar, Yuliia Yuzefovych, Eva-Maria Wittauer, Oliver Beetz, Constança Figueiredo, Rainer Blasczyk, Chen Chen-Wacker, Felix Oldhafer, Marco Carvalho-Oliveira, Christine S. Falk
Publikováno v:
Journal of Cellular and Molecular Medicine
In contrast to the whole liver, primary hepatocytes are highly immunogenic. Thus, alternative strategies of immunomodulation after hepatocyte transplantation are of special interest. Silencing of HLA class I expression is expected to reduce the stren
Autor:
Marco Carvalho Oliveira, Katharina Jansson, Constanca Figueiredo, Gregor Warnecke, Chen Chen-Wacker, Mark Kuehnel, Axel Haverich, Rainer Blasczyk, Klaus Hoeffler
Publikováno v:
Human Immunology. 79:8
Aim HLA and minor antigen mismatches are the main causes of allograft rejection and graft failure. We have shown in mice and rats that MHC silenced cells and tissues are protected against immune rejection. We also demonstrated in porcine lungs that S