Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Marco Bruno Morelli"'
Autor:
Marco Bruno Morelli, Chiara Bongiovanni, Silvia Da Pra, Carmen Miano, Francesca Sacchi, Mattia Lauriola, Gabriele D’Uva
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Chemotherapy and targeted therapies have significantly improved the prognosis of oncology patients. However, these antineoplastic treatments may also induce adverse cardiovascular effects, which may lead to acute or delayed onset of cardiac dysfuncti
Externí odkaz:
https://doaj.org/article/841c511ff53f40b1a5d3e55dac2448e0
Publikováno v:
ESC Heart Failure, Vol 7, Iss 1, Pp 285-289 (2020)
Abstract Aims We hypothesize that specific microRNAs (miRNAs) within cardiomyocyte‐derived exosomes play a pivotal role in the phenoconversion of cardiac myofibroblasts following myocardial infarction (MI). Methods and results We used an establishe
Externí odkaz:
https://doaj.org/article/c9f8133d774c49988b24155bb85df4a6
Autor:
Chiara Bongiovanni, Francesca Sacchi, Silvia Da Pra, Elvira Pantano, Carmen Miano, Marco Bruno Morelli, Gabriele D'Uva
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Despite considerable efforts carried out to develop stem/progenitor cell-based technologies aiming at replacing and restoring the cardiac tissue following severe damages, thus far no strategies based on adult stem cell transplantation have been demon
Externí odkaz:
https://doaj.org/article/c0cbd644bde1437bbbcc34f1f4d999dd
Autor:
Giorgio Aquila, Cinzia Fortini, Antonio Pannuti, Serena Delbue, Micaela Pannella, Marco Bruno Morelli, Cristiana Caliceti, Fausto Castriota, Monica de Mattei, Alessia Ongaro, Agnese Pellati, Pasquale Ferrante, Lucio Miele, Luigi Tavazzi, Roberto Ferrari, Paola Rizzo, Alberto Cremonesi
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-14 (2017)
Abstract Background The lack of early diagnosis, progression markers and effective pharmacological treatment has dramatic unfavourable effects on clinical outcomes in patients with peripheral artery disease (PAD). Addressing these issues will require
Externí odkaz:
https://doaj.org/article/9e1246f8b9fa43e4a5a52d1518ad5a9e
Autor:
Jessica Gambardella, Wafiq Khondkar, Marco Bruno Morelli, Xujun Wang, Gaetano Santulli, Valentina Trimarco
Publikováno v:
Biomedicines, Vol 8, Iss 8, p 277 (2020)
Arginine (L-arginine), is an amino acid involved in a number of biological processes, including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide production. In this systematic review, we focus on the functional role of
Externí odkaz:
https://doaj.org/article/853a27b3061a4b3fb512f03da224c080
Autor:
Paola eRizzo, Donato eMele, Cristiana eCaliceti, Cinzia eFortini, Anthony George Clementz, Marco Bruno Morelli, Giorgio eAquila, Pietro eAmeri, Roberto eFerrari
Publikováno v:
Frontiers in Oncology, Vol 4 (2015)
Targeting the Notch pathway is a new promising therapeutic approach for cancer patients. Inhibition of Notch is effective in the oncology setting because it causes a reduction of highly proliferative tumor cells and it inhibits survival of cancer ste
Externí odkaz:
https://doaj.org/article/73530d876a8145a1947314c7a547374d
Autor:
Cristiana Caliceti, Giorgio Aquila, Micaela Pannella, Marco Bruno Morelli, Cinzia Fortini, Paolo Pinton, Massimo Bonora, Silvana Hrelia, Antonio Pannuti, Lucio Miele, Paola Rizzo, Roberto Ferrari
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71440 (2013)
Estrogens play a protective role in coronary artery disease. The mechanisms of action are still poorly understood, although a role for estrogens in stimulation of angiogenesis has been suggested. In several cell types, estrogens modulate the Notch pa
Externí odkaz:
https://doaj.org/article/ebe7e8eefd654597a8d74c39a69f6c19
Publikováno v:
Expert Opin Ther Targets
INTRODUCTION: Angiopoietin-like (ANGPTL) proteins belong to a family of eight secreted factors that are structurally related to proteins that modulate angiogenesis; these are commonly known as angiopoietins. Angiopoietin-like proteins, ANGPTL3, ANGPT
Publikováno v:
JACC: Basic to Translational Science
Heart failure is an important, and growing, cause of morbidity and mortality. Half of patients with heart failure have preserved ejection fraction, for whom therapeutic options are limited. Here we report that cardiac bridging integrator 1 gene thera
Autor:
Marco Bruno Morelli, Xujun Wang, Pasquale Mone, Jessica Gambardella, Vanessa Castellanos, Gaetano Santulli
Publikováno v:
Expert Opin Drug Discov
INTRODUCTION: Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular calcium (Ca(2+)) release channels located on the endoplasmic/sarcoplasmic reticulum. The availability of the structure of the ligand-binding domain of IP3Rs has enabled th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1256ec98f6cdb1a9bd392fcb1cf06f67
http://hdl.handle.net/11588/831639
http://hdl.handle.net/11588/831639