Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marco Boettger"'
Autor:
Niels Bauer, Marco Boettger, Styliani Papadaki, Tanja Leitner, Stefan Klostermann, Hubert Kettenberger, Guy Georges, Vincent Larraillet, Dino Gluhacevic von Kruechten, Lars Hillringhaus, Annette Vogt, Simon Ausländer, Oliver Popp
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
We present a detailed mass spectrometric analysis of three 2 + 1 T-cell bispecific monoclonal antibodies (TCB mAbs), where an unexpected +15.9950 Da mass shift in tryptic peptides was observed. This modification was attributed to the occurrence of 5R
Externí odkaz:
https://doaj.org/article/57438583073e46798b89828262bbeaca
Autor:
Marco Boettger, Jens Fischer, Christophe Boetsch, Juha Lindner, Jörg Benz, Friederike Hesse, Mario Perro, Marta Cañamero, Pablo Umana, Guy Georges, Patrick Alexander Aaron Weber, Victor Levitsky, Standford Chen, Adrian Zwick, Alexander Bujotzek, Merlind Muecke, Henry Kao, Stefanie Bendels, Georg Fertig, Stephane Leclair, Laura Codarri Deak, Matthias Fueth, Valeria Lifke, Stefan Dengl, Christian Klein, Sonja Offner, Sara Colombetti, Stefan Seeber, Laura Lauener
Publikováno v:
Cancer Research. 80:2270-2270
Based on the unprecedented clinical efficacy of PD-1/PD-L1 pathway checkpoint inhibitors (CPI), non-redundant immune checkpoints like TIM-3, LAG-3, TIGIT or BTLA are currently being targeted, by combinatorial approaches using monospecific or bispecif
Autor:
Christian Hertweck, Keishi Ishida, Kyle L. Dunbar, Sébastien Coyne, Agnieszka Litomska, Marco Boettger
Publikováno v:
Angewandte Chemie (International ed. in English). 57(36)
6-Thioguanine (6TG) is a DNA-targeting therapeutic used in the treatment of various cancers. While 6TG was rationally designed as a proof of concept for antimetabolite therapy, it is also a rare thioamide-bearing bacterial natural product and critica