Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Marco Binder"'
Autor:
Felix Hiebinger, Aiste Kudulyte, Huanting Chi, Sebastian Burbano De Lara, Doroteja Ilic, Barbara Helm, Hendrik Welsch, Viet Loan Dao Thi, Ursula Klingmüller, Marco Binder
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-24 (2023)
Abstract Type I interferons (IFNs) play a central role not only in innate immunity against viral infection, but also in the antitumour response, e.g. through a direct impact on cell proliferation. Particularly for cancer arising in the context of chr
Externí odkaz:
https://doaj.org/article/ea529176236041bc8f2ed5dbe215ae0e
Autor:
Allan Hildesheim, Tim Waterboer, Julia Butt, Mitchell H Gail, Alejandro Calderón, Rolando Herrero, Carolina Porras, Bernal Cortes, Viviana Loría, Amada Aparicio, Gloriana Barrientos, Daniela Retana, Kaiyuan Sun, Rebeca Ocampo, D. Rebecca Prevots, Michael Zúñiga, Roy Wong-McClure, Melvin Morera, Marco Binder, Arturo Abdelnour, Ruth M Pfeiffer, Cristina Barboza Solís, Romain Fantin, Juan Carlos Vanegas, Rachel Mercado, Carlos Ávila
Publikováno v:
BMJ Open, Vol 13, Iss 12 (2023)
Purpose The RESPIRA cohort aims to describe the nature, magnitude, time course and efficacy of the immune response to SARS-CoV-2 infection and vaccination, population prevalence, and household transmission of COVID-19.Participants From November 2020,
Externí odkaz:
https://doaj.org/article/7a40c3b8191647a2b1b163cf7a27a64b
Autor:
Romain Fantin, Neha Agarwala, Amada Aparicio, Ruth Pfeiffer, Tim Waterboer, Arturo Abdelnour, Julia Butt, Julia Flock, Kim Remans, D. Rebecca Prevots, Carolina Porras, Allan Hildesheim, Viviana Loria, Mitchell H. Gail, Rolando Herrero, Alejandro Calderón, Karla Moreno, Melvin Morera, Roy Wong, Roberto Castro, Bernal Cortés, Rebecca Ocampo, Michael Zúñiga, Juan Carlos Vanegas, Kaiyuan Sun, Cristina Barboza-Solís, Marco Binder
Publikováno v:
The Lancet Regional Health. Americas, Vol 27, Iss , Pp 100616- (2023)
Summary: Background: The true incidence of SARS-CoV-2 infection in Costa Rica was likely much higher than officially reported, because infection is often associated with mild symptoms and testing was limited by official guidelines and socio-economic
Externí odkaz:
https://doaj.org/article/f219aeb23bad49cd82fa5b7d5ff63bdd
Autor:
Riccardo Pecori, Weicheng Ren, Mohammad Pirmoradian, Xianhuo Wang, Dongbing Liu, Mattias Berglund, Wei Li, Rafail Nikolaos Tasakis, Salvatore Di Giorgio, Xiaofei Ye, Xiaobo Li, Annette Arnold, Sandra Wüst, Martin Schneider, Karthika-Devi Selvasaravanan, Yvonne Fuell, Thorsten Stafforst, Rose-Marie Amini, Kristina Sonnevi, Gunilla Enblad, Birgitta Sander, Björn Engelbrekt Wahlin, Kui Wu, Huilai Zhang, Dominic Helm, Marco Binder, F. Nina Papavasiliou, Qiang Pan-Hammarström
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106864- (2023)
Summary: Diffuse large B cell lymphoma (DLBCL) is one of the most common types of aggressive lymphoid malignancies. Here, we explore the contribution of RNA editing to DLBCL pathogenesis. We observed that DNA mutations and RNA editing events are ofte
Externí odkaz:
https://doaj.org/article/06e7c6d062c04ab1819616c3c1a37e1a
Autor:
Carolin Zitzmann, Christopher Dächert, Bianca Schmid, Hilde van der Schaar, Martijn van Hemert, Alan S Perelson, Frank J M van Kuppeveld, Ralf Bartenschlager, Marco Binder, Lars Kaderali
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 4, p e1010423 (2023)
Plus-strand RNA viruses are the largest group of viruses. Many are human pathogens that inflict a socio-economic burden. Interestingly, plus-strand RNA viruses share remarkable similarities in their replication. A hallmark of plus-strand RNA viruses
Externí odkaz:
https://doaj.org/article/e39053271cc943da86c1d0cfb984c664
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-10 (2022)
Abstract Properly responding to DNA damage is vital for eukaryotic cells, including the induction of DNA repair, growth arrest and, as a last resort to prevent neoplastic transformation, cell death. Besides being crucial for ensuring homeostasis, the
Externí odkaz:
https://doaj.org/article/0c687c3a76444845bafb869c4b7def0a
Autor:
Christopher J. Neufeldt, Berati Cerikan, Mirko Cortese, Jamie Frankish, Ji-Young Lee, Agnieszka Plociennikowska, Florian Heigwer, Vibhu Prasad, Sebastian Joecks, Sandy S. Burkart, David Y. Zander, Baskaran Subramanian, Rayomand Gimi, Seetharamaiyer Padmanabhan, Radhakrishnan Iyer, Mathieu Gendarme, Bachir El Debs, Niels Halama, Uta Merle, Michael Boutros, Marco Binder, Ralf Bartenschlager
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Neufeldt et al. evaluate transcriptional and cytokine secretion profiles of cells and patient sera following SARS-CoV-2 infection and detect distinct upregulation of inflammatory cytokines. They also demonstrate that this upregulation is mediated by
Externí odkaz:
https://doaj.org/article/e74d2975b29b4848bc2c7e84d04fd670
Autor:
Riccardo Pecori, Isabel Chillón, Claudio Lo Giudice, Annette Arnold, Sandra Wüst, Marco Binder, Marco Marcia, Ernesto Picardi, Fotini Nina Papavasiliou
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Despite hundreds of RNA modifications described to date, only RNA editing results in a change in the nucleotide sequence of RNA molecules compared to the genome. In mammals, two kinds of RNA editing have been described so far, adenosine to inosine (A
Externí odkaz:
https://doaj.org/article/0a436a508c1a41ffa1230acaf8099786
Autor:
Beatrice T. Laudenbach, Karsten Krey, Quirin Emslander, Line Lykke Andersen, Alexander Reim, Pietro Scaturro, Sarah Mundigl, Christopher Dächert, Katrin Manske, Markus Moser, Janos Ludwig, Dirk Wohlleber, Andrea Kröger, Marco Binder, Andreas Pichlmair
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
RNA of some viruses is protected from degradation by a 5′ triphosphate group. Here the authors identify nudix hydrolase 2 (NUDT2) as novel antiviral defense protein that dephosphorylates viral RNA and thereby enables its degradation.
Externí odkaz:
https://doaj.org/article/83808abd13804cb1901e95ef41afb37f
Autor:
Mitchell G. Kluesner, Rafail Nikolaos Tasakis, Taga Lerner, Annette Arnold, Sandra Wüst, Marco Binder, Beau R. Webber, Branden S. Moriarity, Riccardo Pecori
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 515-523 (2021)
We present MultiEditR (Multiple Edit Deconvolution by Inference of Traces in R), the first algorithm specifically designed to detect and quantify RNA editing from Sanger sequencing (z.umn.edu/multieditr). Although RNA editing is routinely evaluated b
Externí odkaz:
https://doaj.org/article/6ae1106ace65443689c12fb1b0a3e6cd