Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marco B, Schaaf"'
Autor:
Jelle Verhoeven, Kathryn A Jacobs, Francesca Rizzollo, Francesca Lodi, Yichao Hua, Joanna Poźniak, Adhithya Narayanan Srinivasan, Diede Houbaert, Gautam Shankar, Sanket More, Marco B Schaaf, Nikolina Dubroja Lakic, Maarten Ganne, Jochen Lamote, Johan Van Weyenbergh, Louis Boon, Oliver Bechter, Francesca Bosisio, Yasuo Uchiyama, Mathieu JM Bertrand, Jean Christophe Marine, Diether Lambrechts, Gabriele Bergers, Madhur Agrawal, Patrizia Agostinis
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-25 (2023)
Abstract Tumor endothelial cells (TECs) actively repress inflammatory responses and maintain an immune‐excluded tumor phenotype. However, the molecular mechanisms that sustain TEC‐mediated immunosuppression remain largely elusive. Here, we show t
Externí odkaz:
https://doaj.org/article/bbcea8700d3946d0a54b3724c68d12c4
Autor:
Marco B. Schaaf, Diede Houbaert, Odeta Meçe, San Kit To, Maarten Ganne, Hannelore Maes, Patrizia Agostinis
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Cancer cell-stromal cell crosstalk is orchestrated by a plethora of ligand-receptor interactions generating a tumor microenvironment (TME) which favors tumor growth. The high pro-angiogenic nature of the TME perpetuates the chaotic network of structu
Externí odkaz:
https://doaj.org/article/2b8edf2f58d5435990cab0d500e19790
Autor:
Judith, Hounjet, Roger, Habets, Marco B, Schaaf, Tessa C, Hendrickx, Lydie M O, Barbeau, Sanaz, Yahyanejad, Kasper M, Rouschop, Arjan J, Groot, Marc, Vooijs
Publikováno v:
Oncogene. 38(27)
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive cancer arising from T-cell progenitors. Although current treatments, including chemotherapy and glucocorticoids, have significantly improved survival, T-ALL remains a fatal disease and new