Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Marco Aurelio, Krieger"'
Autor:
Otacilio C. Moreira, Alice Gomes Fernandes, Natalia Lins da Silva Gomes, Carolina Messias dos Santos, Thiago Jacomasso, Alexandre Dias Tavares Costa, Lucas de O. Rossetti Nascimento, Alejandro Marcel Hasslocher-Moreno, Pedro Emmanuel Alvarenga Americano do Brasil, Luis Gustavo Morello, Fabricio Klerynton Marchini, Marco Aurelio Krieger, Constança Britto
Publikováno v:
Life, Vol 13, Iss 6, p 1236 (2023)
In the absence of validated biomarkers to control the cure of Chagas disease, PCR-based diagnosis is being used as the main tool for an early indication of therapeutic failure. However, since it is considered a technique of complex reproducibility, m
Externí odkaz:
https://doaj.org/article/7ecc1aca7ffa4dc7a750874ad043947f
Autor:
Fernanda Saloum de Neves Manta, Thiago Jacomasso, Rita de Cássia Pontello Rampazzo, Suelen Justo Maria Moreira, Najua M Zahra, Stewart T Cole, Charlotte Avanzi, Thyago Leal-Calvo, Sidra Ezidio Gonçalves Vasconcellos, Phillip Suffys, Marcelo Ribeiro-Alves, Marco Aurelio Krieger, Alexandre Dias Tavares Costa, Milton Ozório Moraes
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 2, p e0009850 (2022)
Leprosy is a chronic dermato-neurological disease caused by Mycobacterium leprae, an obligate intracellular bacterium. Timely detection is a challenge in leprosy diagnosis, relying on clinical examination and trained health professionals. Furthermore
Externí odkaz:
https://doaj.org/article/9eb1604e210244ddab1884dd60d1b4c4
Autor:
Christian Macagnan Probst, Myllena de Fátima Alheiros Dias Melo, Daniela Parada Pavoni, Max Jean de Ornelas Toledo, Tainah Silva Galdino, Adeilton Alves Brandão, Constança Britto, Marco Aurelio Krieger
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 116 (2021)
BACKGROUND Trypanosoma cruzi is an important human pathogen in Latin America with nearly seven million people infected. It has a large degree of genetic diversity, classified into six discrete typing units (DTUs), which probably influences its physio
Externí odkaz:
https://doaj.org/article/f584c3f2b3d94fc18768f23b7548b38e
Autor:
Fernanda Saloum de Neves Manta, Thyago Leal-Calvo, Suelen Justo M Moreira, Brunna L C Marques, Marcelo Ribeiro-Alves, Patrícia S Rosa, José Augusto C Nery, Rita de Cássia Pontello Rampazzo, Alexandre Dias Tavares Costa, Marco Aurelio Krieger, Milton Ozório Moraes
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 5, p e0008325 (2020)
Leprosy urgently needs a precise and early diagnostic tool. The sensitivity of the direct (bacilli staining, Mycobacterium leprae DNA) and indirect (antibody levels, T cell assays) diagnostics methods vary based on the clinical form. Recently, PCR-ba
Externí odkaz:
https://doaj.org/article/fc8b0c55953a497a81a46acc45e48411
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background Trypanosomatids are a group of protozoan parasites that includes the etiologic agents of important human illnesses as Chagas disease, sleeping sickness and leishmaniasis. These parasites have a significant distinction from other e
Externí odkaz:
https://doaj.org/article/bec9c58ebf204ee18701f673c2de2e25
Autor:
Nasir Ali, Graziele Lima Bello, Maria Lúcia Rosa Rossetti, Marco Aurelio Krieger, Alexandre Dias Tavares Costa
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0242408 (2020)
We sought to develop a smooth and low cost sample preparation and DNA extraction protocol, streamlined with a ready-to-use qPCR in a portable instrument to overcome some of the existing hurdles. Several solutions were evaluated as to their ability to
Externí odkaz:
https://doaj.org/article/5b985fc7ee6c40eeba2b1e7ed56140e1
Autor:
Afranio Kritski, Draurio Barreira, Ana Paula Junqueira-Kipnis, Milton Ozorio Moraes, Maria Martha Campos, Wim Mauritz Degrave, Silvana Spindola Miranda, Marco Aurelio Krieger, Erica Chimara, Carlos Morel, Margareth Pretti Dalcolmo, Ethel Leonor Noia Maciel, Maria do Socorro Nantua Evangelista, Teresa Scatena Villa, Mauro Sanchez, Fernanda Dockhorn Costa, Inacio Queiroz, Martha Maria Oliveira, Ruy Souza Junior, Jose Roberto Lapa e Silva, Antonio Ruffino-Netto
Publikováno v:
Revista da Sociedade Brasileira de Medicina Tropical, Vol 49, Iss 1, Pp 135-145 (2016)
Externí odkaz:
https://doaj.org/article/b372a5cd811c4d75a514d4360b40f9ab
Autor:
Fernanda G Kugeratski, Michel Batista, Alexandre Haruo Inoue, Bruno Dias Ramos, Marco Aurelio Krieger, Fabricio K Marchini/
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 110, Iss 5, Pp 687-690 (2015)
The functional characterisation of thousands of Trypanosoma cruzi genes remains a challenge. Reverse genetics approaches compatible with high-throughput cloning strategies can provide the tool needed to tackle this challenge. We previously published
Externí odkaz:
https://doaj.org/article/32a07c7f3d834be29ca2e0c068284e9d
Autor:
Tiago Feitosa Mota, Claudia Ida Brodskyn, Luis Gustavo Morello, Fabricio Klerynton Marchini, Marco Aurelio Krieger, Rita Cássia Pontello Rampazzo, Deborah Bittencourt Mothé Fraga
Publikováno v:
Medical and veterinary entomologyREFERENCES. 36(2)
The study aimed to develop a multiplex qPCR to detect Leishmania infantum load in different sandfly sample settings using Leishmania kDNA and sandfly vacuolar ATPase (VATP) subunit C as internal control gene. The amplification of Lutzomyia longipalpi
Autor:
Marco Aurelio Krieger, Andrea Rodrigues Ávila, Sueli Fumie Yamada Ogatta, Claire Plazanet-Menut, Samuel Goldenberg
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 94, Pp 165-168 (1999)
The transformation of epimastigotes into metacyclic trypomastigotes involves changes in the pattern of expressed genes, resulting in important morphological and functional differences between these developmental forms of Trypanosoma cruzi. In order t
Externí odkaz:
https://doaj.org/article/041613fe7e9241b1a6b90bce4f19df5e