Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Marco Antonio STEPHANO"'
Autor:
Rodolfo Ferreira Marques, Wagner Quintilio, Marcos Camargo Knirsch, Tamara Mieco Fucase, Patrick Jack Spencer, Marco Antonio Stephano
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract The treatment with hyperimmune sera constitute the only specific and effective therapy available against snakebite envenomation, most common in developing countries. Serum quality is an important factor on patient recovery time and in the in
Externí odkaz:
https://doaj.org/article/ed7ecd1754b146258e29b75fada10165
Autor:
Camila Hiromi Chiba, Marcos Camargo Knirsch, Adriano Rodrigues Azzoni, Antonio R Moreira, Marco Antonio Stephano
Publikováno v:
BioTechniques, Vol 70, Iss 2, Pp 126-133 (2021)
Biopharmaceutical products are of great importance in the treatment or prevention of many diseases and represent a growing share of the global pharmaceutical market. The usual technology for protein synthesis (cell-based expression) faces certain obs
Externí odkaz:
https://doaj.org/article/1617ae5244c741a5903ade4f0664222f
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract Lung cancer is the leading cause of cancer deaths worldwide. Small cell lung cancer (SCLC) accounts for approximately 15% of all lung cancer cases. Despite a frequently good response to first-line treatment with chemotherapy and/or radiother
Externí odkaz:
https://doaj.org/article/1b536fbb79f64eeabd1c048a99ae0a36
Autor:
Juliana Souza Ribeiro Costa, Marília Medeiros, Edite Harumi Yamashiro-Kanashiro, Mussya Cisotto Rocha, Paulo Cesar Cotrim, Marco Antonio Stephano, Marcelo Lancellotti, Guilherme Diniz Tavares, Laura Oliveira-Nascimento
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 5, p e0007388 (2019)
Most treatments of leishmaniasis require hospitalization and present side effects or parasite resistance; innovations in drug formulation/reposition can overcome these barriers and must be pursued to increase therapeutic alternatives. Therefore, we t
Externí odkaz:
https://doaj.org/article/72ac2e4e074c46f8983e06efc598ccb4
Autor:
Rosalvo GUIDOLIN, Josefina Farina MORAIS, Marco Antonio STEPHANO, José Roberto MARCELINO, Ivone Kazuko YAMAGUCHI, Hisako Gondo HIGASHI
Publikováno v:
Revista do Instituto de Medicina Tropical de São Paulo, Vol 39, Iss 2, Pp 119-122 (1997)
Reduction of complement activation through an alteration of the Fc fragment of immunoglobulins by b-propiolactone treatment was carried out in equine antisera raised against rabies virus, Bothrops venoms and diphtherial toxin. Results were evaluated
Externí odkaz:
https://doaj.org/article/8af7ebfcda364f7ea08c8d21433c0118
Autor:
Keity Souza Santos, Marco Antonio Stephano, José Roberto Marcelino, Virginia Maria Resende Ferreira, Thalita Rocha, Celso Caricati, Hisako Gondo Higashi, Ana Maria Moro, Jorge Elias Kalil, Osmar Malaspina, Fabio Fernandes Morato Castro, Mário Sérgio Palma
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79971 (2013)
Victims of massive bee attacks become extremely ill, presenting symptoms ranging from dizziness and headache to acute renal failure and multiple organ failure that can lead to death. Previous attempts to develop specific antivenom to treat these vict
Externí odkaz:
https://doaj.org/article/21ebdf64ffa14cae9fd9718174363e87
Autor:
Marco Antonio Stephano
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
Enzimas, biofármacos e produtos de origem biológica de modo geral sempre foram obstáculos para o uso terapêutico. Isto em função dos riscos de reação adversa que poderiam ocasionar bem como a indução de uma resposta imunológica desejável
Autor:
Cristofher Victor Vivas, Jennifer Adriane dos Santos, Yan Borges Barreto, Sergio Hiroshi Toma, Jonnatan Julival dos Santos, Marco Antonio Stephano, Cristiano Luis Pinto de Oliveira, Koiti Araki, Adriano Mesquita Alencar, Antonio Carlos Bloise
Nowadays the bactericidal and antimicrobial properties of silver nanoparticles, AgNPs, in addition to their cytotoxic effects, have been explored to properly modulate cell biochemistry processes in order to improve the healing of wounds. Herein we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e4a3c6abe7e0c3976950cc80ab753c
https://doi.org/10.21203/rs.3.rs-2227171/v1
https://doi.org/10.21203/rs.3.rs-2227171/v1
Autor:
Luiza de O. Macedo, Ivan A. C. Morales, Eduardo J. Barbosa, Marco Antonio STEPHANO, Gabriel de Araujo, Nadia B. Chacra
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd34bed73dfdf76c471d04348c1291fa
https://doi.org/10.2139/ssrn.4160333
https://doi.org/10.2139/ssrn.4160333
Publikováno v:
Pharmaceutical Biotechnology ISBN: 9781003178361
This chapter focuses on quality aspects that can be directly measured on process and product to assure efficacy, safety and stability of the product physicochemical profile. The first case study of a Quality-by-Design-based biopharmaceutical developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26e9cf8b87184a9d100361a3c0509b58
https://doi.org/10.1201/9781003178361-21
https://doi.org/10.1201/9781003178361-21