Sais de Índio (III) promovendo reações orgânicas: IIn(SePh)2 como fonte de fenil-selenolato

Autor: Marco Antonio Ceschi, Clovis Peppe, Carlos Alberto Fernandes de Oliveira

Publikováno v: Revista Principia, Vol 0, Iss 7, Pp 33-34 (1999)

Compostos de índio no estado de oxidação +I são raros.

Externí odkaz: https://doaj.org/article/0681813a12bc4a3fa7caae766510a40b

Expedient Microwave-Assisted Synthesis of Bis(n)-lophine Analogues as Selective Butyrylcholinesterase Inhibitors: Cytotoxicity Evaluation and Molecular Modelling

Autor: Isabella A. Guedes, Aline Rigon Zimmer, Laurent E. Dardenne, Brunella Biscussi, Ana Julia Soares, Marco Antonio Ceschi, Thaís Carine Ruaro, Viktor Saraiva Câmara, Ana Paula Murray

Publikováno v: Journal of the Brazilian Chemical Society v.32 n.6 2021
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 32, Issue: 6, Pages: 1173-1185, Published: 02 JUN 2021

In the brain of patients with chronic Alzheimer’s disease (AD), the butyrylcholinesterase (BuChE) levels rise while the acetylcholinesterase (AChE) levels decrease. Therefore, development of new selective BuChE inhibitors is of vital importance. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55deba62717d1b48e725630c04a829e
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532021000601173

An Expedient Synthesis of Tacrine-Squaric Hybrids as Potent, Selective and Dual‑Binding Cholinesterase Inhibitors

Autor: Isabella A. Guedes, Blessing A. Afolabi, Henrique Dapont, Marco Antonio Ceschi, Renan Michael Pilotti, João Paulo Bizarro Lopes, João Rocha, Laurent E. Dardenne

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 31, Issue: 5, Pages: 857-866, Published: 30 APR 2020

The restoration of acetylcholine levels in the brain by inhibition of cholinesterases is currently the most successful therapeutic strategy to treat neurodegenerative disorders. In this context, tacrine has been largely investigated as a starting sca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745874ce83913d1bcb91a53c3ddc16dc
https://doi.org/10.21577/0103-5053.20200019

Lophine and pyrimidine based photoactive molecular hybrids. Synthesis, photophysics, BSA interaction and DFT study

Autor: Viktor Saraiva Camara, Paulo Goncalves, Fabiano Rodembusch, Nilda Vargas Barbosa, Dennis Russowsky, Roiney Beal, João Paulo Bizarro Lopes, Marco Antonio Ceschi, Joao Batista Teixeira da Rocha, Pablo Andrei Nogara, Fabiano Da Silveira Santos

Publikováno v: New Journal of Chemistry. 42:17126-17137

Two photoactive molecular hybrids containing both lophine and pyrimidine moieties were synthesized by multicomponent reaction. The compounds present absorption in the UV-region (below 300 nm) and fluorescence emission in the violet region due to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::edcebd4fb4c2325d06485b3b0600e01d
https://doi.org/10.1039/c8nj03315c

Tianeptine Esters Derivatives: A Study of Protein-Drug Interaction Performed by Fluorescence Quenching and Molecular Docking

Autor: Leandra Franciscato Campo, Marco Antonio Ceschi, Franciela Arenhart Soares, Paulo A. Netz, Vanessa Petry do Canto, Daniel B. Franceschini

Publikováno v: Journal of the Brazilian Chemical Society v.30 n.10 2019
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 30, Issue: 10, Pages: 2125-2135, Published: 21 OCT 2019

The nature of binding between bovine serum albumin (BSA) and the antidepressant tianeptine and a new series of esters derivatives were studied in this paper. The interactions with BSA were investigated by UV-Vis and fluorescence spectroscopy at three

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d258ec383176b882ceee99ef1c001a77
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532019001002125