Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Marco Annandale"'
1
Akademický článek
Methods for detection of cardiac glycogen-autophagy
Autor: Parisa Koutsifeli, Lorna J. Daniels, Joshua Neale, Sarah Fong, Upasna Varma, Marco Annandale, Xun Li, Yohanes Nursalim, James R. Bell, Kate L. Weeks, Aleksandr Stotland, David J. Taylor, Roberta A. Gottlieb, Lea M.D. Delbridge, Kimberley M. Mellor
Publikováno v: Autophagy Reports, Vol 3, Iss 1 (2024)
Glycogen-autophagy (‘glycophagy’) is a selective autophagy process involved in delivering glycogen to the lysosome for bulk degradation. Glycophagy protein intermediaries include STBD1 as a glycogen tagging receptor, delivering the glycogen cargo
Externí odkaz: https://doaj.org/article/896be00534814dda8ffacc5947942049
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2
Akademický článek
Elevated myocardial fructose and sorbitol levels are associated with diastolic dysfunction in diabetic patients, and cardiomyocyte lipid inclusions in vitro
Autor: Lorna J. Daniels, Marco Annandale, Parisa Koutsifeli, Xun Li, Carol T. Bussey, Isabelle van Hout, Richard W. Bunton, Philip J. Davis, Sean Coffey, Rajesh Katare, Regis R. Lamberts, Lea M. D. Delbridge, Kimberley M. Mellor
Publikováno v: Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Diabetes is associated with cardiac metabolic disturbances and increased heart failure risk. Plasma fructose levels are elevated in diabetic patients. A direct role for fructose involvement in diabetic heart pathology has not been investigat
Externí odkaz: https://doaj.org/article/71cc5f2d30f7420783f9df21ea649854
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3
Glycogen-autophagy: molecular machinery and cellular mechanisms of glycophagy
Autor: Parisa Koutsifeli, Upasna Varma, Lorna J. Daniels, Marco Annandale, Xun Li, Joshua P.H. Neale, Sarah Hayes, Kate L. Weeks, Samuel James, Lea M.D. Delbridge, Kimberley M. Mellor
Autophagy is an essential cellular process involving degradation of superfluous or defective macromolecules and organelles as a form of homeostatic recycling. Initially proposed to be a "bulk" degradation pathway, a more nuanced appreciation of selec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50264938f0a42db528b10483520df879
https://ora.ox.ac.uk/objects/uuid:f992b919-a36d-41b1-b7bd-2c824c8b5f4a
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4
Fructose metabolism and cardiac metabolic stress
Autor: S. L. James, H. A. Ambalawanar, L.M.D. Delbridge, Kimberley M. Mellor, J. P. H. Neale, Marco Annandale, A. H. L. Chau, L. J. Daniels, Parisa Koutsifeli, X. Li
Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Cardiovascular disease is one of the leading causes of mortality in diabetes. High fructose consumption has been linked with the development of diabetes and cardiovascular disease. Serum and cardiac tissue fructose levels are elevated in diabetic pat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808653870e7046de0ea178e2b7a212ab
https://ora.ox.ac.uk/objects/uuid:71340f71-7b78-477b-98c3-703571b7777f
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6
Glycophagy — the physiological perspective on a newly characterized glycogen-selective autophagy
Autor: Lea M.D. Delbridge, Parisa Koutsifeli, Sarah P.T. Fong, Marco Annandale, Kate L. Weeks, James R. Bell, Kimberley M. Mellor
Publikováno v: Current Opinion in Physiology. 30:100598
Degradation of intracellular components through autophagy is a fundamental process to maintain cellular integrity and homeostasis. Recently a glycogen-selective autophagy pathway has been described, termed ‘glycophagy’. Glycogen is a primary stor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8bc965d0b95777a78ff6564eb5d044
https://doi.org/10.1016/j.cophys.2022.100598
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8
Elevated myocardial fructose and sorbitol levels are associated with diastolic dysfunction in diabetic patients, and cardiomyocyte lipid inclusions in vitro
Autor: Rajesh Katare, L. Daniels, Parisa Koutsifeli, Carol T. Bussey, Isabelle van Hout, Sean Coffey, Kimberley M. Mellor, Lea M.D. Delbridge, Philip Davis, Richard W. Bunton, Regis R. Lamberts, Marco Annandale, X. Li
Publikováno v: Nutrition & Diabetes
Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-7 (2021)
Diabetes is associated with cardiac metabolic disturbances and increased heart failure risk. Plasma fructose levels are elevated in diabetic patients. A direct role for fructose involvement in diabetic heart pathology has not been investigated. The g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ee8d2fb60a03b9afd7dd8ec208aea6
https://doi.org/10.1038/s41387-021-00150-7
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9
Myocardial energy stress, autophagy induction, and cardiomyocyte functional responses
Autor: Marco Annandale, L. Daniels, Kimberley M. Mellor, Eleia Chan, Lea M.D. Delbridge, U. Varma
Publikováno v: Antioxidants and Redox Signaling. 31(6)
Significance: Energy stress in the myocardium occurs in a variety of acute and chronic pathophysiological contexts, including ischemia, nutrient deprivation, and diabetic disease settings of substrate disturbance. Although the heart is highly adaptiv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f87757b0fbc38588a5caba7f9b72506
http://ora.ox.ac.uk/objects/uuid:
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