Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Marco Abesser"'
Autor:
Franziska Werner, Estefania Prentki Santos, Konstanze Michel, Hanna Schrader, Katharina Völker, Tamara Potapenko, Lisa Krebes, Marco Abeßer, Dorothe Möllmann, Martin Schlattjan, Hannes Schmidt, Boris V. Skryabin, Katarina Špiranec Spes, Kai Schuh, Christopher P. Denton, Hideo A. Baba, Michaela Kuhn
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Excessive activation of cardiac fibroblasts (CFs) in response to injury provokes cardiac fibrosis, stiffness, and failure. The local mediators counterregulating this response remain unclear. Exogenous C-type natriuretic peptide (CNP) exerts antifibro
Externí odkaz:
https://doaj.org/article/7283f518feaf421cb1374fda596e995c
Autor:
Simone Pickel, Yiliam Cruz-Garcia, Sandra Bandleon, Katalin Barkovits, Cornelia Heindl, Katharina Völker, Marco Abeßer, Kathy Pfeiffer, Alice Schaaf, Katrin Marcus, Petra Eder-Negrin, Michaela Kuhn, Erick Miranda-Laferte
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
L-type voltage-gated calcium channels (LTCCs) regulate crucial physiological processes in the heart. They are composed of the Cavα1 pore-forming subunit and the accessory subunits Cavβ, Cavα2δ, and Cavγ. Cavβ is a cytosolic protein that regulat
Externí odkaz:
https://doaj.org/article/495d0eff559d40d68167f7a27d6ea5de
Autor:
Konstanze Michel, Melissa Herwig, Franziska Werner, Katarina Špiranec Spes, Marco Abeßer, Kai Schuh, Swati Dabral, Andreas Mügge, Hideo A. Baba, Boris V. Skryabin, Nazha Hamdani, Michaela Kuhn
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
Heart failure is often accompanied by titin-dependent myocardial stiffness. Phosphorylation of titin by cGMP-dependent protein kinase I (PKGI) increases cardiomyocyte distensibility. The upstream pathways stimulating PKGI-mediated titin phosphorylati
Externí odkaz:
https://doaj.org/article/bc488a37aaa24a19ac2437a35f753e5f
Autor:
Denis Hepbasli, Sina Gredy, Melanie Ullrich, Amelie Reigl, Marco Abeßer, Thomas Raabe, Kai Schuh
Publikováno v:
Brain Sciences, Vol 11, Iss 10, p 1365 (2021)
Vocalization is an important part of social communication, not only for humans but also for mice. Here, we show in a mouse model that functional deficiency of Sprouty-related EVH1 domain-containing 2 (SPRED2), a protein ubiquitously expressed in the
Externí odkaz:
https://doaj.org/article/61961403a09145818af2c4c1b4cfc5f3
Autor:
Leticia Prates Roma, Anna-Florentine Schiuma, Kai Schuh, Martin van der Laan, Jan Dudek, Julia Schwemmlein, Sarah Atighetchi, Michael Böhm, Edoardo Bertero, Christopher Carlein, Andreas Müller, Carolin Brune, Peter Rehling, Markus Hoth, Andrey Kazakov, Michaela Kuhn, Mathias Hohl, Christoph Maack, Ulrich Laufs, Michael Kohlhaas, Vasco Sequeira, Ilona Kutschka, Marco Abeßer, Kai Münker, Alexander Nickel, Reinhard Kappl, Karina von der Malsburg, Alexander von der Malsburg
Publikováno v:
Circulation. 144:1694-1713
Background: Barth syndrome (BTHS) is caused by mutations of the gene encoding tafazzin, which catalyzes maturation of mitochondrial cardiolipin and often manifests with systolic dysfunction during early infancy. Beyond the first months of life, BTHS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dc7d7ca51902412ab37f2eea26fcb04
https://doi.org/10.1161/circulationaha.121.053755
https://doi.org/10.1161/circulationaha.121.053755
Autor:
Marco Abeßer, Frank Schweda, Petra Eder Negrin, Katharina Völker, Kai Schuh, Antonella Cellini, Lisa Krebes, Viacheslav O. Nikolaev, Franz Hofmann, Alexander Nickel, Katarina Špiranec Spes, Michaela Kuhn, Wen Chen
Publikováno v:
Hypertension. 76:1637-1648
Cardiac ANP (atrial natriuretic peptide) moderates arterial blood pressure. The mechanisms mediating its hypotensive effects are complex and involve inhibition of the renin-angiotensin-aldosterone system, increased natriuresis, endothelial permeabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1dc8397e8bd1859babc9698f11b84c
https://doi.org/10.1161/hypertensionaha.120.15772
https://doi.org/10.1161/hypertensionaha.120.15772
Autor:
Edoardo, Bertero, Alexander, Nickel, Michael, Kohlhaas, Mathias, Hohl, Vasco, Sequeira, Carolin, Brune, Julia, Schwemmlein, Marco, Abeßer, Kai, Schuh, Ilona, Kutschka, Christopher, Carlein, Kai, Münker, Sarah, Atighetchi, Andreas, Müller, Andrey, Kazakov, Reinhard, Kappl, Karina, von der Malsburg, Martin, van der Laan, Anna-Florentine, Schiuma, Michael, Böhm, Ulrich, Laufs, Markus, Hoth, Peter, Rehling, Michaela, Kuhn, Jan, Dudek, Alexander, von der Malsburg, Leticia, Prates Roma, Christoph, Maack
Publikováno v:
Circulation. 144(21)
Barth syndrome (BTHS) is caused by mutations of the gene encoding tafazzin, which catalyzes maturation of mitochondrial cardiolipin and often manifests with systolic dysfunction during early infancy. Beyond the first months of life, BTHS cardiomyopat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcf43f159d12506e4114c3628bb70e29
https://pubmed.ncbi.nlm.nih.gov/34648376
https://pubmed.ncbi.nlm.nih.gov/34648376
Autor:
Simone, Pickel, Yiliam, Cruz-Garcia, Sandra, Bandleon, Katalin, Barkovits, Cornelia, Heindl, Katharina, Völker, Marco, Abeßer, Kathy, Pfeiffer, Alice, Schaaf, Katrin, Marcus, Petra, Eder-Negrin, Michaela, Kuhn, Erick, Miranda-Laferte
Publikováno v:
Frontiers in Cardiovascular Medicine
L-type voltage-gated calcium channels (LTCCs) regulate crucial physiological processes in the heart. They are composed of the Cavα1 pore-forming subunit and the accessory subunits Cavβ, Cavα2δ, and Cavγ. Cavβ is a cytosolic protein that regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e11e4e8c0048461ee2b647f768d88440
https://pubmed.ncbi.nlm.nih.gov/34307509
https://pubmed.ncbi.nlm.nih.gov/34307509
Autor:
Swati Dabral, Marco Abeßer, Kai Schuh, Andreas Mügge, Franziska Werner, Katarina Špiranec Spes, Hideo A. Baba, Boris V. Skryabin, Konstanze Michel, Melissa Herwig, Nazha Hamdani, Michaela Kuhn
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
JCI Insight
JCI Insight
Heart failure is often accompanied by titin-dependent myocardial stiffness. Phosphorylation of titin by cGMP-dependent protein kinase I (PKGI) increases cardiomyocyte distensibility. The upstream pathways stimulating PKGI-mediated titin phosphorylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b1fe0b9e3e2a63568d62bb8ec44725
https://doaj.org/article/bc488a37aaa24a19ac2437a35f753e5f
https://doaj.org/article/bc488a37aaa24a19ac2437a35f753e5f
Autor:
Wolfgang A. Linke, Peter M. Benz, Ralf Erkens, Andreas Unger, Hannes Häbich, Sandra Umbenhauer, Kai Schuh, Benjamin Aßmus, Helga Wagner, Michaela Kuhn, Stefan Frantz, Jorge Martin Machado, Hideo A. Baba, Anahi-Paula Arias-Loza, Melanie Ullrich, Anne Marie Augustin, Marco Abeßer, Franziska Werner
Cardiac functionality is dependent on a balanced protein turnover. Accordingly, regulated protein decay is critical to maintain cardiac function. Here we demonstrate that deficiency of SPRED2, an intracellular repressor of ERK-MAPK signaling markedly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e98c38b70e7dbec7b2124acf7005a3d
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85061543232
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85061543232
