Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Marco A. S. de Souza"'
Autor:
Milton A. D. Torres, Aurea Echevarria, Marilene M. Canto-Cavalheiro, Léa Cysne-Finkelstein, Leonor L. Leon, Marco A. S. de Souza
Publikováno v:
Arzneimittelforschung. 50:925-928
In a previous work, searching for new drugs with high efficiency and low toxicity, the in vitro antileishmanial activity of a series of seven amidine derivatives against Leishmania amazonensis promastigotes was reported. In order to compare the poten
Autor:
Claude Pirmez, Aurea Echevarria, Lenor L. Leon, Marco A. S. de Souza, Antônio José da Silva-Gonçalves, Mônica Sertã, Léa Cysne-Finkelstein, Rosane Maria Temporal
Publikováno v:
Arzneimittel-Forschung. 52(6)
In this work, the effect of amidine derivatives (with bromine and methoxy as substituents) in the "in vitro" parasite-macrophage interaction was evaluated. The potential toxicity was also analyzed. The results show that the methoxy-derivative was abl