Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Marco A. J. Iafolla"'
Autor:
Parneet K. Cheema, Marco A. J. Iafolla, Husam Abdel-Qadir, Andrew B. Bellini, Nazira Chatur, Natasha Chandok, Vikram R. Comondore, Morven Cunningham, Ilana Halperin, Anne B. Hu, Diana Jaskolka, Saeed Darvish-Kazem, Masud H. Khandaker, Abhijat Kitchlu, Jasdip S. Sachdeva, Shane Shapera, Nicholas R. J. Woolnough, Massey Nematollahi
Publikováno v:
Current Oncology, Vol 31, Iss 10, Pp 6356-6383 (2024)
The increased use of immune checkpoint inhibitors (ICIs) across cancer programs has created the need for standardized monitoring and management of immune-related adverse events (irAEs). Delayed recognition without appropriate treatment can have serio
Externí odkaz:
https://doaj.org/article/3e38519628c5425cabe1255ed3c8d53e
Autor:
Parneet K. Cheema, Marco A. J. Iafolla, Massey Nematollahi, FeRevelyn Berco, Deepanjali Kaushik, Priscilla Matthews, William R. Raskin, Kirstin A. Perdrizet, Shaan Dudani, Juhi Husain, Margaret Balcewicz, Philip G. Kuruvilla, Stephen M. Reingold, Henry J. Conter
Publikováno v:
Current Oncology, Vol 29, Iss 2, Pp 869-880 (2022)
The increased use of immune checkpoint inhibitors across cancer programs has created the need for standardized patient assessment, education, monitoring, and management of immune-related adverse events (irAEs). At William Osler Health System in Bramp
Externí odkaz:
https://doaj.org/article/a6006115821a4207b3e6e19870a4a5d7
Autor:
Brandon S. Sheffield, Andrea Beharry, Joanne Diep, Kirstin Perdrizet, Marco A. J. Iafolla, William Raskin, Shaan Dudani, Mary Anne Brett, Blerta Starova, Brian Olsen, Parneet K. Cheema
Publikováno v:
Current Oncology, Vol 29, Iss 3, Pp 1326-1334 (2022)
Purpose: Biomarker data are critical to the delivery of precision cancer care. The average turnaround of next-generation sequencing (NGS) reports is over 2 weeks, and in-house availability is typically limited to academic centers. Lengthy turnaround
Externí odkaz:
https://doaj.org/article/52d2618297474676ad438d2b00ac7538
Autor:
Esmail M. Al‐Ezzi, Husam A. Alqaisi, Marco A. J. Iafolla, Lisa Wang, Srikala S. Sridhar, Adrian G. Sacher, Nazanin Fallah‐Rad, Di M. Jiang, Geoffrey A. Watson, Charles N. Catton, Padraig R. Warde, Rob J. Hamilton, Neil E. Fleshner, Alexandre R. Zlotta, Aaron R. Hansen
Publikováno v:
Cancer Medicine, Vol 10, Iss 17, Pp 5775-5782 (2021)
Abstract Background In men with metastatic castration‐resistant prostate cancer (mCRPC) with primarily bone metastases, radium‐223 (223Ra) improves overall survival (OS). However, the selection of 223Ra is not guided by specific validated clinico
Externí odkaz:
https://doaj.org/article/da392819a41c4b0387329a1e9a5afd5b
Autor:
S. Y. Cindy Yang, Scott C. Lien, Ben X. Wang, Derek L. Clouthier, Youstina Hanna, Iulia Cirlan, Kelsey Zhu, Jeffrey P. Bruce, Samah El Ghamrasni, Marco A. J. Iafolla, Marc Oliva, Aaron R. Hansen, Anna Spreafico, Philippe L. Bedard, Stephanie Lheureux, Albiruni Razak, Vanessa Speers, Hal K. Berman, Alexey Aleshin, Benjamin Haibe-Kains, David G. Brooks, Tracy L. McGaha, Marcus O. Butler, Scott V. Bratman, Pamela S. Ohashi, Lillian L. Siu, Trevor J. Pugh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Although circulating tumour DNA (ctDNA) can predict immune checkpoint blockade (ICB) responses, its association with tumour biomarkers remains unknown. Here, the authors use ctDNA to inform exome and transcriptome profiling of >100 patients with 30 c
Externí odkaz:
https://doaj.org/article/2a55653c8f4a4ed888f461e4bdb5696f
Autor:
Lillian L. Siu, Samah El Ghamrasni, Aaron R. Hansen, Pamela S. Ohashi, David G. Brooks, Benjamin Haibe-Kains, Alexey Aleshin, S. Y. Cindy Yang, Hal K. Berman, Marc Oliva, Stephanie Lheureux, Albiruni Ryan Abdul Razak, Scott V. Bratman, Kelsey Zhu, Ben X. Wang, Jeff Bruce, Marco A. J. Iafolla, Tracy L. McGaha, Marcus O. Butler, Youstina Hanna, Anna Spreafico, Philippe L. Bedard, Scott C. Lien, Trevor J. Pugh, Derek L. Clouthier, Iulia Cirlan, Vanessa Speers
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Serial circulating tumor DNA (ctDNA) monitoring is emerging as a non-invasive strategy to predict and monitor immune checkpoint blockade (ICB) therapeutic efficacy across cancer types. Yet, limited data exist to show the relationship between ctDNA dy
Autor:
Philippe L. Bedard, Youstina Hanna, Jenna Eagles, Derek L. Clouthier, Alexey Aleshin, Himanshu Sethi, Iulia Cirlan, Marco A. J. Iafolla, Svetlana Shchegrova, Aaron R. Hansen, Scott C. Lien, Paul Billings, Trevor J. Pugh, Scott V. Bratman, Maggie C. Louie, Anna Spreafico, Wei Xu, S. Y. Cindy Yang, Albiruni Ryan Abdul Razak, Pamela S. Ohashi, Zhihui Liu, Stephanie Lheureux, Kayla Marsh, Lillian L. Siu, Bernhard Zimmermann, Dax Torti
Publikováno v:
Nature Cancer. 1:873-881
Immune checkpoint blockade (ICB) provides clinical benefit to a subset of patients with cancer. However, existing biomarkers do not reliably predict treatment response across diverse cancer types. Limited data exist to show how serial circulating tum
Autor:
Bradley Alexander McGregor, Daniel Y.C. Heng, Shaan Dudani, Giovanni Zanotti, Georg A. Bjarnason, Ulka N. Vaishampayan, Frede Donskov, Lynn Huynh, J. Connor Wells, Marco A. J. Iafolla, John A. Steinharter, Aaron R. Hansen, Mei Sheng Duh, Marie-France Savard, Jeffrey Graham, Rose Chang
Publikováno v:
Savard, M F, Wells, J C, Graham, J, Dudani, S, Steinharter, J A, McGregor, B A, Donskov, F, Bjarnason, G A, Vaishampayan, U N, Hansen, A R, Iafolla, M A J, Zanotti, G, Huynh, L, Chang, R, Duh, M S & Heng, D Y C 2020, ' Real-World Assessment of Clinical Outcomes Among First-Line Sunitinib Patients with Clear Cell Metastatic Renal Cell Carcinoma (mRCC) by the International mRCC Database Consortium Risk Group ', Oncologist, vol. 25, no. 5, pp. 422-430 . https://doi.org/10.1634/theoncologist.2019-0605
Oncologist
Oncologist
Background International Metastatic Renal Cell Carcinoma (mRCC) Database Consortium (IMDC) risk groups are important when considering therapeutic options for first-line treatment. Materials and Methods Adult patients with clear cell mRCC initiating f
Autor:
Parneet K. Cheema, Marco A. J. Iafolla, Massey Nematollahi, FeRevelyn Berco, Deepanjali Kaushik, Priscilla Matthews, William R. Raskin, Kirstin A. Perdrizet, Shaan Dudani, Juhi Husain, Margaret Balcewicz, Philip G. Kuruvilla, Stephen M. Reingold, Henry J. Conter
Publikováno v:
Current oncology (Toronto, Ont.). 29(2)
The increased use of immune checkpoint inhibitors across cancer programs has created the need for standardized patient assessment, education, monitoring, and management of immune-related adverse events (irAEs). At William Osler Health System in Bramp
Autor:
Yada Kanjanapan, Jordan J. Feld, Morven Cunningham, Bettina E. Hansen, Lillian L. Siu, Philippe L. Bedard, Marco A. J. Iafolla, Orlando Cerocchi, Kendra Ross, Anna Spreafico, Marcus O. Butler
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0253070 (2021)
PLoS ONE, Vol 16, Iss 6, p e0253070 (2021)
Background and aims Immune checkpoint inhibitors (ICI) are increasingly used in cancer therapy. Elevated liver enzymes frequently occur in patients treated with ICI but evaluation is poorly described. We sought to better understand causes of liver en