Výsledky vyhledávání - "Marco A. C. Versluis"

Lymphadenectomy and Adjuvant Therapy Improve Survival with Uterine Carcinosarcoma: A Large Retrospective Cohort Study

Autor: Cindy Pielsticker, Maaike A. van der Aa, Marco A. C. Versluis, Hans W. Nijman, Harry Hollema, Marco de Bruyn

Publikováno v: Oncology : journal of clinical and experimental cancer research, 95(2), 100-108. KARGER

Objective: Uterine carcinosarcoma is a rare, aggressive subtype of endometrial cancer. Treatment consists of hysterectomy, bilateral salpingo-oophorectomy, and lymphadenectomy (LND). The survival benefit of LND in relation to adjuvant radio- and/or c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2fc7ab46bbcfd3a5c25db5980a2436f
https://doi.org/10.1159/000488531

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The prognostic benefit of tumour-infiltrating Natural Killer cells in endometrial cancer is dependent on concurrent overexpression of Human Leucocyte Antigen-E in the tumour microenvironment

Autor: Harry Hollema, Marco A. C. Versluis, S. Marchal, M. de Bruyn, Hans W. Nijman, T. van Hall, G. H. de Bock, Annechien Plat

Publikováno v: European Journal of Cancer, 86, 285. Elsevier Limited
European Journal of Cancer, 86, 285-295
European Journal of Cancer, 86, 285-295. ELSEVIER SCI LTD

Background: Human Leucocyte Antigen-E (HLA-E) has been reported as both a positive and negative prognostic marker in cancer. This apparent discrepancy may be due to opposing actions of HLA-E on tumour-infiltrating immune cells. Therefore, we evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756d3ed0a23dca540ec0ff05eea1e22d
https://doi.org/10.1016/j.ejca.2017.09.008

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Immunological, molecular and therapeutic mechanisms in endometrial cancer

Autor: Marco A. C. Versluis

Improving outcome for patients with endometrial cancer (EC) has fueled research into immunological, molecular and therapeutic mechanisms in EC. The research in this thesis aims to further increase our understanding of the interplay between these mech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34af2a9607f49820c02673fbf0ea732
https://doi.org/10.33612/diss.97965520

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CD103 defines intraepithelial CD8+ PD1+ tumour-infiltrating lymphocytes of prognostic significance in endometrial adenocarcinoma

Autor: Hagma H. Workel, Marco de Bruyn, Evelien W. Duiker, Annechien Plat, G. Bea A. Wisman, Harry Hollema, Marian J.E. Mourits, Maartje C.A. Wouters, Hans W. Nijman, Florine A. Eggink, Henriette J. G. Arts, R. Yigit, Harry G. Klip, Fenne L. Komdeur, Maaike H. M. Oonk, Marco A. C. Versluis

Publikováno v: European Journal of Cancer, 60, 1-11. ELSEVIER SCI LTD

Introduction: Intraepithelial CD8+ tumour-infiltrating T-lymphocytes (TIL) are associated with a prolonged survival in endometrial cancer (EC). By contrast, stromal infiltration of CD8+ TIL does not confer prognostic benefit. A single marker to discr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20db3ae9ecd01bc73878cb0b6e285831
https://doi.org/10.1016/j.ejca.2016.02.026

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L1CAM expression in uterine carcinosarcoma is limited to the epithelial component and may be involved in epithelial-mesenchymal transition

Autor: Camilla Krakstad, Marco A. C. Versluis, Harry Hollema, Annechien Plat, G. H. de Bock, Tjalling Bosse, Xavier Matias-Guiu, J. Trovic, Hans W. Nijman, M. de Bruyn

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Virchows Archiv, 473(5), 591-598
Repositorio Abierto de la UdL
Universitad de Lleida
Virchows Archiv : an International Journal of Pathology, 473(5), 591-598. SPRINGER
Dipòsit Digital de la UB
Universidad de Barcelona

Uterine carcinosarcoma (UCS) has been proposed as a model for epithelial–mesenchymal transition (EMT), a process characterized by a functional change facilitating migration and metastasis in many types of cancer. L1CAMis an adhesion molecule that h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f6723dbdd677295aedc601b5b6cec2e
http://hdl.handle.net/2445/172130

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Prediction model for regional or distant recurrence in endometrial cancer based on classical pathological and immunological parameters

Autor: Emma J Crosbie, Carien L. Creutzberg, Helen Mackay, Vincent T.H.B.M. Smit, R A de Jong, Linda Mileshkin, Hans W. Nijman, Toos Daemen, Marco A. C. Versluis, Richard J. Edmondson, Henry C Kitchener, Alexandra Leary, Harry Hollema, Annechien Plat, G. H. de Bock, Tjalling Bosse, Melanie E Powell

Publikováno v: British Jounal of Cancer, 113(5), 786-793. Nature Publishing Group
British Journal of Cancer, 113(5), 786-793
British Journal of Cancer

Background: Adjuvant therapy increases disease-free survival in endometrial cancer (EC), but has no impact on overall survival and negatively influences the quality of life. We investigated the discriminatory power of classical and immunological pred

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1c5f02ed97af838865ea83e28b57d9
https://research.rug.nl/en/publications/189d2088-fe51-4432-9751-e3ff43f6958e

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Microsatellite instability derived JAK1 frameshift mutations are associated with tumor immune evasion in endometrioid endometrial cancer

Autor: Harry Hollema, Marco de Bruyn, Geertruida H. de Bock, Tjalling Bosse, Ellen Stelloo, Carien L. Creutzberg, Reinhardt H van Dijk, Elisabeth M. Osse, Annechien Plat, Marco A. C. Versluis, Remi A. Nout, Hans W. Nijman, Vincent T.H.B.M. Smit

Publikováno v: Oncotarget, 7(26), 39885-39893
Oncotarget
Oncotarget, 7(26), 39885-39893. Impact Journals LLC

JAK1 frameshift mutations may promote cancer cell immune evasion by impeding upregulation of the antigen presentation pathway in microsatellite unstable endometrial cancers (ECs). This study investigated the JAK1 mutation frequency, its functional im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7078136974e6ceb455428525eb8bc00a
http://hdl.handle.net/1887/112884

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Patients' attitude towards residents' participation during gynaecological surgery

Autor: Marco A. C. Versluis, Paul J.Q. van der Linden

Publikováno v: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 153(2), 203-206. ELSEVIER SCIENCE BV

Objective: To evaluate patients' attitude towards participation of residents in training in gynaecological surgery and patients understanding of resident position.Study design: An observational survey study was performed between July and February 200

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a30a10afb44916f948df9ac33b1f361
https://pubmed.ncbi.nlm.nih.gov/20728982

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Telemedicine: a dream come true?

Autor: Marco A. C. Versluis

Publikováno v: Postgraduate medical journal, 86(1022), 687-687. BMJ PUBLISHING GROUP

The UN millennium goals 4 and 5 aim to reduce child mortality and improve maternal health.1 The international community has done a lot of work to bring us closer to these goals, “… but we are moving much too slow” as UN Secretary-General Ban Ki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f105a018c673d8b51bd12f2d8c7a68c
https://doi.org/10.1136/pgmj.2009.092692

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