Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Marco A Purbhoo"'
Autor:
Rachel E Sanborn, Trisha M Wise-Draper, Marc Van Dijk, Breelyn Wilky, Anthony El-Khoueiry, John Hamm, Benjamin Garmezy, Benedito Carneiro, Jamie Moon, Sue Ryu, Irene R Ramos, Marco A Purbhoo, Dave SB Hoon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b75f2106d8324471995322071f792703
Autor:
Mark W. Lowdell, Winnie Ip, Shreenal Patel, Claire Horlock, Arindam Mitra, Shristi Bhandari, Katy Newton, Marco A. Purbhoo, Amanda Skulte, Alka Stansfield, Waseem Qasim, Anke Friedetzky
Publikováno v:
Cytotherapy. 18:1209-1218
Background aims In pediatric patients, adenovirus (ADV) reactivation after allogeneic hematopoietic stem cell transplantation (allo HSCT) is a major cause of morbidity and mortality. For patients who do not respond to antiviral drug therapy, a new tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402c8efb6434dd3182079e3dd80bb92b
https://doi.org/10.1016/j.jcyt.2016.06.009
https://doi.org/10.1016/j.jcyt.2016.06.009
Autor:
Naveenta Kumar, Fouzia Sadiq, Marco A. Purbhoo, H. Antoniades, Salim I. Khakoo, Sujit Mukherjee, Robert D. Goldin, Fanny Lebossé, Mark Thursz, A. Dhar, Wafa Khamri
Publikováno v:
Journal of Hepatology. 70:e20-e21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15046c5298ad3f9ff73902c455de29e3
https://doi.org/10.1016/s0618-8278(19)30033-7
https://doi.org/10.1016/s0618-8278(19)30033-7
Autor:
Daniel M. Davis, Marco A. Purbhoo, Parvin S. Ahmed, Gwenoline Borhis, Salim I. Khakoo, Mohammed M. Naiyer, Berenice Mbiribindi
Publikováno v:
The Journal of Immunology. 190:2924-2930
Productive engagement of MHC class I by inhibitory NK cell receptors depends on the peptide bound by the MHC class I molecule. Peptide:MHC complexes that bind weakly to killer cell Ig-like receptors (KIRs) can antagonize the inhibition mediated by hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d718c997c1956b3195e250663282a1a7
https://doi.org/10.4049/jimmunol.1201032
https://doi.org/10.4049/jimmunol.1201032
Autor:
Mohammed M, Naiyer, Sorcha A, Cassidy, Andrea, Magri, Vanessa, Cowton, Kevin, Chen, Salah, Mansour, Hariklia, Kranidioti, Berenice, Mbiribindi, Pauline, Rettman, Scott, Harris, Liam J, Fanning, Arend, Mulder, Franz H J, Claas, Andrew D, Davidson, Arvind H, Patel, Marco A, Purbhoo, Salim I, Khakoo
Publikováno v:
Science immunology. 2(15)
Killer cell immunoglobulin-like receptors (KIRs) are rapidly evolving species-specific natural killer (NK) cell receptors associated with protection against multiple different human viral infections. We report that the activating receptor KIR2DS2 dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1131f765a7cc8cc82f41830185a5707
https://pubmed.ncbi.nlm.nih.gov/28916719
https://pubmed.ncbi.nlm.nih.gov/28916719
Autor:
Marco A. Purbhoo
Publikováno v:
Immunological Reviews. 251:36-48
Summary The immune synapse is central to the regulation of T-cell activation and effector functions. Vesicular compartments dynamically interact with the immune synapse. Here they take part in the trafficking of signaling components to and from the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c03c592e3294f1f6622f22f2383228
https://doi.org/10.1111/imr.12012
https://doi.org/10.1111/imr.12012
Autor:
Ruth Moysey, Tara Mahon, Andrew K. Sewell, Deborah H. Sutton, Anita Milicic, Peter Eamon Molloy, Annelise Vuidepot, Richard G. Carroll, Rodney E. Phillips, Bent K. Jakobsen, James L. Riley, Angel Varela-Rohena, Yi Li, Steven M. Dunn, Brian Cameron, Megan M. Suhoski, Bruno E. Laugel, Marco A. Purbhoo, David K. Cole, Carl H. June
Publikováno v:
Nature Medicine. 14:1390-1395
HIV's considerable capacity to vary its HLA-I-restricted peptide antigens allows it to escape from host cytotoxic T lymphocytes (CTLs). Nevertheless, therapeutics able to target HLA-I-associated antigens, with specificity for the spectrum of preferre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9421793372c1b32c9d3dd414d6c85d4c
https://doi.org/10.1038/nm.1779
https://doi.org/10.1038/nm.1779
Publikováno v:
Cytotherapy. 10:633-641
The discovery of new drugs has occasionally led to a better understanding of biologic processes and unforeseen therapeutic applications. One such example is the new group of tyrosine kinase inhibitors, exemplified by the Bcr-Abl inhibitor imatinib (G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4fafb321d28d760a343984140f0697
https://doi.org/10.1080/14653240802317639
https://doi.org/10.1080/14653240802317639
Autor:
Emma Gostick, David Price, Rebecca Ashfield, Joanna E. Brewer, Marco A. Purbhoo, Brendan J. Classon, Bruno Laugel, Bent K. Jakobsen, Brian Cameron, Deborah H. Sutton, Anita Milicic, Yi Li, Andrew K. Sewell, Ruth Moysey, Emma Baston, Nathaniel Liddy, Giovanna Bossi, Alan D. Bennett
Publikováno v:
Molecular Cancer Therapeutics. 6:2081-2091
Tumor-associated human telomerase reverse transcriptase (hTERT) is expressed in >85% of human tumors but not in most normal cells. As a result, this antigen has received considerable attention from those interested in cancer immunotherapy. Specifical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f092980eb1fa31069d763c01eacd2f17
https://doi.org/10.1158/1535-7163.mct-07-0092
https://doi.org/10.1158/1535-7163.mct-07-0092
Autor:
Kwasi, Kwakwa, Alexander, Savell, Timothy, Davies, Ian, Munro, Simona, Parrinello, Marco A, Purbhoo, Chris, Dunsby, Mark A A, Neil, Paul M W, French
Publikováno v:
Journal of biophotonics. 9(9)
TIRF and STORM microscopy are super-resolving fluorescence imaging modalities for which current implementations on standard microscopes can present significant complexity and cost. We present a straightforward and low-cost approach to implement STORM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0938994352bb6b169977e5ab968e8cc1
https://pubmed.ncbi.nlm.nih.gov/27592533
https://pubmed.ncbi.nlm.nih.gov/27592533