Zobrazeno 1 - 10
of 422
pro vyhledávání: '"Marco A M Prado"'
Autor:
Sudesna Chakraborty, Roy A. M. Haast, Kate M. Onuska, Prabesh Kanel, Marco A. M. Prado, Vania F. Prado, Ali R. Khan, Taylor W. Schmitz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Cortical cholinergic projections originate from subregions of the basal forebrain (BF). To examine its organization in humans, we computed multimodal gradients of BF connectivity by combining 7 T diffusion and resting state functional MRI. M
Externí odkaz:
https://doaj.org/article/4309096a79a2481a992268a71e9788f8
Autor:
Mariana Gavioli, Aline Lara, Pedro W M Almeida, Augusto Martins Lima, Denis D Damasceno, Cibele Rocha-Resende, Marina Ladeira, Rodrigo R Resende, Patricia M Martinelli, Marcos Barrouin Melo, Patricia C Brum, Marco Antonio Peliky Fontes, Robson A Souza Santos, Marco A M Prado, Silvia Guatimosim
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100179 (2014)
Cholinergic control of the heart is exerted by two distinct branches; the autonomic component represented by the parasympathetic nervous system, and the recently described non-neuronal cardiomyocyte cholinergic machinery. Previous evidence has shown
Externí odkaz:
https://doaj.org/article/c2ca11c35bd142bfba48e8d39b5bbbb8
Autor:
Hermann A Rodrigues, Matheus de C Fonseca, Wallace L Camargo, Patrícia M A Lima, Patrícia M Martinelli, Lígia A Naves, Vânia F Prado, Marco A M Prado, Cristina Guatimosim
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78342 (2013)
In vertebrates, nerve muscle communication is mediated by the release of the neurotransmitter acetylcholine packed inside synaptic vesicles by a specific vesicular acetylcholine transporter (VAChT). Here we used a mouse model (VAChT KD(HOM)) with 70%
Externí odkaz:
https://doaj.org/article/b5e39797f3a84a2b9c9312c42f7c8c27
Autor:
Ashbeel Roy, Aline Lara, Diogo Guimarães, Rita Pires, Eneas R Gomes, David E Carter, Marcus V Gomez, Silvia Guatimosim, Vania F Prado, Marco A M Prado, Robert Gros
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39997 (2012)
Autonomic dysfunction is observed in many cardiovascular diseases and contributes to cardiac remodeling and heart disease. We previously reported that a decrease in the expression levels of the vesicular acetylcholine transporter (VAChT) in genetical
Externí odkaz:
https://doaj.org/article/5914918505cb42bc87b9df72c5e4d88c
Autor:
Monica S Guzman, Xavier De Jaeger, Sanda Raulic, Ivana A Souza, Alex X Li, Susanne Schmid, Ravi S Menon, Raul R Gainetdinov, Marc G Caron, Robert Bartha, Vania F Prado, Marco A M Prado
Publikováno v:
PLoS Biology, Vol 9, Iss 11, p e1001194 (2011)
Cholinergic neurons in the striatum are thought to play major regulatory functions in motor behaviour and reward. These neurons express two vesicular transporters that can load either acetylcholine or glutamate into synaptic vesicles. Consequently ch
Externí odkaz:
https://doaj.org/article/b8e704cc8e744454b8e838e381964c94
Autor:
Cristina Martins-Silva, Xavier De Jaeger, Monica S Guzman, Ricardo D F Lima, Magda S Santos, Christopher Kushmerick, Marcus V Gomez, Marc G Caron, Marco A M Prado, Vania F Prado
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17611 (2011)
Defining the contribution of acetylcholine to specific behaviors has been challenging, mainly because of the difficulty in generating suitable animal models of cholinergic dysfunction. We have recently shown that, by targeting the vesicular acetylcho
Externí odkaz:
https://doaj.org/article/4ac73b1ec9294da192a0874c76d99dd4
Autor:
Sadik Bay, Chander S. Digwal, Ananda M. Rodilla Martín, Sahil Sharma, Aleksandra Stanisavljevic, Anna Rodina, Anoosha Attaran, Tanaya Roychowdhury, Kamya Parikh, Eugene Toth, Palak Panchal, Eric Rosiek, Chiranjeevi Pasala, Ottavio Arancio, Paul E. Fraser, Melissa J. Alldred, Marco A. M. Prado, Stephen D. Ginsberg, Gabriela Chiosis
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1252 (2024)
Neurodegenerative disorders, including Alzheimer’s disease (AD) and Parkinson’s disease (PD), represent debilitating conditions with complex, poorly understood pathologies. Epichaperomes, pathologic protein assemblies nucleated on key chaperones,
Externí odkaz:
https://doaj.org/article/4dbcf551145247a7b517292e9d2527fa
Autor:
Sara Memar, Eric Jiang, Vania F. Prado, Lisa M. Saksida, Timothy J. Bussey, Marco A. M. Prado
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-13 (2023)
Abstract Open access to rodent cognitive data has lagged behind the rapid generation of large open-access datasets in other areas of neuroscience, such as neuroimaging and genomics. One contributing factor has been the absence of uniform standardizat
Externí odkaz:
https://doaj.org/article/1935e4365c724f179b5f09c6b0cbce55
Autor:
Miguel Skirzewski, Oren Princz-Lebel, Liliana German-Castelan, Alycia M. Crooks, Gerard Kyungwook Kim, Sophie Henke Tarnow, Amy Reichelt, Sara Memar, Daniel Palmer, Yulong Li, R. Jane Rylett, Lisa M. Saksida, Vania F. Prado, Marco A. M. Prado, Timothy J. Bussey
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Nucleus accumbens cholinergic interneurons release acetylcholine and glutamate. Here, authors show that acetylcholine, rather than glutamate, is predominantly involved in updating dopamine dynamics mediating Pavlovian approach behaviours.
Externí odkaz:
https://doaj.org/article/f4d1dc4e75374f81957db4a31c2850f0
Autor:
Xiaoyun Xu, Matthew Cowan, Flavio Beraldo, Amy Schranz, Patrick McCunn, Nicole Geremia, Zalman Brown, Maitray Patel, Karen L. Nygard, Reza Khazaee, Lihong Lu, Xingyu Liu, Michael J. Strong, Gregory A. Dekaban, Ravi Menon, Robert Bartha, Mark Daley, Haojie Mao, Vania Prado, Marco A. M. Prado, Lisa Saksida, Tim Bussey, Arthur Brown
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-27 (2021)
Abstract We have previously reported long-term changes in the brains of non-concussed varsity rugby players using magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) and functional magnetic imaging (fMRI). Others have reported cogni
Externí odkaz:
https://doaj.org/article/8a4b058cb2f44d0f99bb08a4296f09b7