Zobrazeno 1 - 10
of 399
pro vyhledávání: '"Marco A Coelho"'
Autor:
Marco A Coelho, Márcia David-Palma, Terrance Shea, Katharine Bowers, Sage McGinley-Smith, Arman W Mohammad, Andreas Gnirke, Andrey M Yurkov, Minou Nowrousian, Sheng Sun, Christina A Cuomo, Joseph Heitman
Publikováno v:
PLoS Biology, Vol 22, Iss 6, p e3002682 (2024)
In exploring the evolutionary trajectories of both pathogenesis and karyotype dynamics in fungi, we conducted a large-scale comparative genomic analysis spanning the Cryptococcus genus, encompassing both global human fungal pathogens and nonpathogeni
Externí odkaz:
https://doaj.org/article/7d4fb4fbff1a4c5cbc0badce4e9fce91
Autor:
Andrew Ryan Passer, Shelly Applen Clancey, Terrance Shea, Márcia David-Palma, Anna Floyd Averette, Teun Boekhout, Betina M Porcel, Minou Nowrousian, Christina A Cuomo, Sheng Sun, Joseph Heitman, Marco A Coelho
Publikováno v:
eLife, Vol 11 (2022)
Sexual reproduction is a ubiquitous, ancient eukaryotic trait. While most sexual organisms have to find a mating partner, species as diverse as animals, plants, and fungi have evolved the ability to reproduce sexually without requiring another indivi
Externí odkaz:
https://doaj.org/article/c4c8b2e7b5fb448f82773746fdc8c47d
Autor:
Ci Fu, Aaliyah Davy, Simeon Holmes, Sheng Sun, Vikas Yadav, Asiya Gusa, Marco A Coelho, Joseph Heitman
Publikováno v:
PLoS Genetics, Vol 17, Iss 11, p e1009935 (2021)
Genome copy number variation occurs during each mitotic and meiotic cycle and it is crucial for organisms to maintain their natural ploidy. Defects in ploidy transitions can lead to chromosome instability, which is a hallmark of cancer. Ploidy in the
Externí odkaz:
https://doaj.org/article/c33c415486c340caad11ea79ca74d83e
Autor:
Shelby J Priest, Marco A Coelho, Verónica Mixão, Shelly Applen Clancey, Yitong Xu, Sheng Sun, Toni Gabaldón, Joseph Heitman
Publikováno v:
PLoS Genetics, Vol 17, Iss 1, p e1008871 (2021)
Hybridization has resulted in the origin and variation in extant species, and hybrids continue to arise despite pre- and post-zygotic barriers that limit their formation and evolutionary success. One important system that maintains species boundaries
Externí odkaz:
https://doaj.org/article/337fa6e2fd9644cc92a567870e3cb15d
Autor:
Yufeng Fang, Marco A Coelho, Haidong Shu, Klaas Schotanus, Bhagya C Thimmappa, Vikas Yadav, Han Chen, Ewa P Malc, Jeremy Wang, Piotr A Mieczkowski, Brent Kronmiller, Brett M Tyler, Kaustuv Sanyal, Suomeng Dong, Minou Nowrousian, Joseph Heitman
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008646 (2020)
Centromeres are chromosomal regions that serve as platforms for kinetochore assembly and spindle attachments, ensuring accurate chromosome segregation during cell division. Despite functional conservation, centromere DNA sequences are diverse and oft
Externí odkaz:
https://doaj.org/article/3f08afed9e0a4bb9a2e31162032e496d
Autor:
Sundar Ram Sankaranarayanan, Giuseppe Ianiri, Marco A Coelho, Md Hashim Reza, Bhagya C Thimmappa, Promit Ganguly, Rakesh Netha Vadnala, Sheng Sun, Rahul Siddharthan, Christian Tellgren-Roth, Thomas L Dawson Jnr, Joseph Heitman, Kaustuv Sanyal
Publikováno v:
eLife, Vol 9 (2020)
Genomic rearrangements associated with speciation often result in variation in chromosome number among closely related species. Malassezia species show variable karyotypes ranging between six and nine chromosomes. Here, we experimentally identified a
Externí odkaz:
https://doaj.org/article/d4c86b0564844bb99bff5e9333b6e56c
Publikováno v:
PLoS Genetics, Vol 15, Iss 9, p e1008365 (2019)
Sexual development is a key evolutionary innovation of eukaryotes. In many species, mating involves interaction between compatible mating partners that can undergo cell and nuclear fusion and subsequent steps of development including meiosis. Mating
Externí odkaz:
https://doaj.org/article/3ed697ba40af462ab5c5f74e5721ee10
Publikováno v:
PLoS Genetics, Vol 9, Iss 6, p e1003587 (2013)
Comparative genomics revealed in the last decade a scenario of rampant horizontal gene transfer (HGT) among prokaryotes, but for fungi a clearly dominant pattern of vertical inheritance still stands, punctuated however by an increasing number of exce
Externí odkaz:
https://doaj.org/article/3561037204624416822fb787521ccdca
Autor:
Jéssica A Gomes-Rezende, Ana G Gomes-Alves, João F Menino, Marco A Coelho, Paula Ludovico, Paula Gonçalves, Mark H J Sturme, Fernando Rodrigues
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47033 (2012)
Recent evidence suggests that Paracoccidioides species have the potential to undergo sexual reproduction, although no sexual cycle has been identified either in nature or under laboratory conditions. In the present work we detected low expression lev
Externí odkaz:
https://doaj.org/article/0dcf0fdecf8f4beb94ee29154bc548e0
Publikováno v:
PLoS Genetics, Vol 6, Iss 8 (2010)
In fungi, sexual identity is determined by specialized genomic regions called MAT loci which are the equivalent to sex chromosomes in some animals and plants. Usually, only two sexes or mating types exist, which are determined by two alternate sets o
Externí odkaz:
https://doaj.org/article/561547135dea4e2a85cb03580463f670