Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Marco Moracci"'
Autor:
Stefano Cinti, Sima Singh, Giovanni Covone, Luca Tonietti, Annarita Ricciardelli, Angelina Cordone, Roberta Iacono, Arianna Mazzoli, Marco Moracci, Alessandra Rotundi, Donato Giovannelli
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The space race is entering a new era of exploration, in which the number of robotic and human missions to various places in our solar system is rapidly increasing. Despite the recent advances in propulsion and life support technologies, there is a gr
Externí odkaz:
https://doaj.org/article/3126398d19c04788a6fb29e43155de5c
Autor:
Antonietta Tarallo, Carla Damiano, Sandra Strollo, Nadia Minopoli, Alessia Indrieri, Elena Polishchuk, Francesca Zappa, Edoardo Nusco, Simona Fecarotta, Caterina Porto, Marcella Coletta, Roberta Iacono, Marco Moracci, Roman Polishchuk, Diego Luis Medina, Paola Imbimbo, Daria Maria Monti, Maria Antonietta De Matteis, Giancarlo Parenti
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 11, Pp 1-21 (2021)
Abstract Pompe disease is a metabolic myopathy due to acid alpha‐glucosidase deficiency. In addition to glycogen storage, secondary dysregulation of cellular functions, such as autophagy and oxidative stress, contributes to the disease pathophysiol
Externí odkaz:
https://doaj.org/article/c9d76b1dfda5478da27f60239b67fa37
Autor:
Martina Aulitto, Andrea Strazzulli, Ferdinando Sansone, Flora Cozzolino, Maria Monti, Marco Moracci, Gabriella Fiorentino, Danila Limauro, Simonetta Bartolucci, Patrizia Contursi
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-17 (2021)
Abstract Background The spore-forming lactic acid bacterium Bacillus coagulans MA-13 has been isolated from canned beans manufacturing and successfully employed for the sustainable production of lactic acid from lignocellulosic biomass. Among lactic
Externí odkaz:
https://doaj.org/article/ba718cd6ae3e41e6ab41aaf0fc01f234
Autor:
Roberta Iacono, Nadia Minopoli, Maria Carmina Ferrara, Antonietta Tarallo, Carla Damiano, Caterina Porto, Sandra Strollo, Véronique Roig-Zamboni, Gianfranco Peluso, Gerlind Sulzenbacher, Beatrice Cobucci-Ponzano, Giancarlo Parenti, Marco Moracci
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 2068-2079 (2021)
Pompe disease is an inherited metabolic disorder due to the deficiency of the lysosomal acid α-glucosidase (GAA). The only approved treatment is enzyme replacement therapy with the recombinant enzyme (rhGAA). Further approaches like pharmacological
Externí odkaz:
https://doaj.org/article/7db4e2f4002a4340b38daa8d1bb2c018
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 114 (2023)
Archaea represents the third domain of life, displaying a closer relationship with eukaryotes than bacteria. These microorganisms are valuable model systems for molecular biology and biotechnology. In fact, nowadays, methanogens, halophiles, thermoph
Externí odkaz:
https://doaj.org/article/df80f78770cb4b8b8a33804238911b24
Autor:
Federica De Lise, Andrea Strazzulli, Roberta Iacono, Nicola Curci, Mauro Di Fenza, Luisa Maurelli, Marco Moracci, Beatrice Cobucci-Ponzano
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Genetic code decoding, initially considered to be universal and immutable, is now known to be flexible. In fact, in specific genes, ribosomes deviate from the standard translational rules in a programmed way, a phenomenon globally termed recoding. Tr
Externí odkaz:
https://doaj.org/article/0bfe613ee4374e0f91a5e78157d5deb7
Autor:
Andrea Strazzulli, Giuseppe Perugino, Marialuisa Mazzone, Mosè Rossi, Stephen G. Withers, Marco Moracci
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 973-980 (2019)
The reaction mechanism of glycoside hydrolases belonging to family 1 (GH1) of carbohydrate-active enzymes classification, hydrolysing β-O-glycosidic bonds, is well characterised. This family includes several thousands of enzymes with more than 20 di
Externí odkaz:
https://doaj.org/article/0530f2b6eba446bd9eb035a48b6d9df8
Autor:
Rosanna Mattossovich, Roberta Iacono, Giuseppina Cangiano, Beatrice Cobucci-Ponzano, Rachele Isticato, Marco Moracci, Ezio Ricca
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-9 (2017)
Abstract Background The Bacillus subtilis spore has long been used to display antigens and enzymes. Spore display can be accomplished by a recombinant and a non-recombinant approach, with the latter proved more efficient than the recombinant one. We
Externí odkaz:
https://doaj.org/article/cc27aff15b384965828df3efdb98dd1c
Autor:
Véronique Roig-Zamboni, Beatrice Cobucci-Ponzano, Roberta Iacono, Maria Carmina Ferrara, Stanley Germany, Yves Bourne, Giancarlo Parenti, Marco Moracci, Gerlind Sulzenbacher
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Pompe disease is caused by mutations in lysosomal acid α-glucosidase (GAA) and patients are being treated with recombinant human α-glucosidase (rhGAA). Here the authors present the crystal structures of rhGAA and its complexes with inhibitors and a
Externí odkaz:
https://doaj.org/article/1092edf30ccd4d65964b3a4b8b5fdd66
Autor:
Federica De Lise, Roberta Iacono, Andrea Strazzulli, Rosa Giglio, Nicola Curci, Luisa Maurelli, Rosario Avino, Antonio Carandente, Stefano Caliro, Alessandra Tortora, Fabio Lorenzini, Paola Di Donato, Marco Moracci, Beatrice Cobucci-Ponzano
Publikováno v:
Molecules, Vol 26, Iss 7, p 1861 (2021)
Genetic decoding is flexible, due to programmed deviation of the ribosomes from standard translational rules, globally termed “recoding”. In Archaea, recoding has been unequivocally determined only for termination codon readthrough events that re
Externí odkaz:
https://doaj.org/article/2c6f2d6a1c4842fe88e443fe6a0f13b0