Zobrazeno 1 - 10
of 297
pro vyhledávání: '"Marco Losa"'
Autor:
Marco Losa, Marc Emmenegger, Pierre De Rossi, Patrick M Schürch, Tetiana Serdiuk, Niccolò Pengo, Danaëlle Capron, Dimitri Bieli, Niklas Bargenda, Niels J Rupp, Manfredi C Carta, Karl J Frontzek, Veronika Lysenko, Regina R Reimann, Petra Schwarz, Mario Nuvolone, Gunilla T Westermark, K Peter R Nilsson, Magdalini Polymenidou, Alexandre PA Theocharides, Simone Hornemann, Paola Picotti, Adriano Aguzzi
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2024-2042 (2024)
Abstract Extracellularly released molecular inflammasome assemblies -ASC specks- cross-seed Aβ amyloid in Alzheimer’s disease. Here we show that ASC governs the extent of inflammation-induced amyloid A (AA) amyloidosis, a systemic disease caused b
Externí odkaz:
https://doaj.org/article/361701b3ccf5457e8ccf997a37e06f01
Autor:
Marco Losa, Yasser Morsy, Marc Emmenegger, Salomon M. Manz, Petra Schwarz, Adriano Aguzzi, Michael Scharl
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Commensal intestinal bacteria shape our microbiome and have decisive roles in preserving host metabolic and immune homeostasis. They conspicuously impact disease development and progression, including amyloid-beta (Aβ) and alpha (α)-synuclein patho
Externí odkaz:
https://doaj.org/article/0103b0e8cf014ae0b00f0ac00548060d
Autor:
Mario Detomas, Katrin Ritzel, Isabella Nasi-Kordhishti, Stefan Wolfsberger, Marcus Quinkler, Marco Losa, Viola Tröger, Matthias Kroiss, Martin Fassnacht, Greisa Vila, Jürgen Bernd Honegger, Martin Reincke, Timo Deutschbein
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveTo evaluate diagnostic accuracy of the corticotropin-releasing hormone (CRH) stimulation test and the overnight 8 mg dexamethasone suppression test (DST) for the differentiation of Cushing’s disease (CD) and ectopic Cushing’s syndrome (E
Externí odkaz:
https://doaj.org/article/f4471333053a43fe8bd82c377faafd46
Autor:
Asvin K K Lakkaraju, Karl Frontzek, Emina Lemes, Uli Herrmann, Marco Losa, Rajlakshmi Marpakwar, Adriano Aguzzi
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 9, Pp 1-17 (2021)
Abstract Brain-matter vacuolation is a defining trait of all prion diseases, yet its cause is unknown. Here, we report that prion infection and prion-mimetic antibodies deplete the phosphoinositide kinase PIKfyve—which controls endolysosomal matura
Externí odkaz:
https://doaj.org/article/bf837fe83aa247b2b6e9fcd8e3b7e998
Autor:
Camilla Recordati, Marcella De Maglie, Claudia Cella, Simona Argentiere, Saverio Paltrinieri, Silvia Bianchessi, Marco Losa, Fabio Fiordaliso, Alessandro Corbelli, Gianpaolo Milite, Federica Aureli, Marilena D’Amato, Andrea Raggi, Francesco Cubadda, Sabina Soldati, Cristina Lenardi, Eugenio Scanziani
Publikováno v:
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-18 (2021)
Abstract Background Widespread use of silver in its different forms raises concerns about potential adverse effects after ingestion, the main exposure route for humans. The aim of this study was to investigate in CD-1 (ICR) male mice the tissue distr
Externí odkaz:
https://doaj.org/article/b038edb23696447b9f4f3f6541df44cd
Autor:
Assunta Senatore, Karl Frontzek, Marc Emmenegger, Andra Chincisan, Marco Losa, Regina Reimann, Geraldine Horny, Jingjing Guo, Sylvie Fels, Silvia Sorce, Caihong Zhu, Nathalie George, Stefan Ewert, Thomas Pietzonka, Simone Hornemann, Adriano Aguzzi
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 9, Pp 1-19 (2020)
Abstract Prion immunotherapy may hold great potential, but antibodies against certain PrP epitopes can be neurotoxic. Here, we identified > 6,000 PrP‐binding antibodies in a synthetic human Fab phage display library, 49 of which we characterized in
Externí odkaz:
https://doaj.org/article/c41b503363134ee683fd9afef525f6b5
Publikováno v:
Expert Review of Endocrinology & Metabolism. :1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fc4f1a1015c33ed837587ef784a6906
https://doi.org/10.1080/17446651.2023.2216794
https://doi.org/10.1080/17446651.2023.2216794
Autor:
Mario Detomas, Katrin Ritzel, Isabella Nasi-Kordhishti, Marie Helene Schernthaner-Reiter, Marco Losa, Viola Tröger, Barbara Altieri, Matthias Kroiss, Ralph Kickuth, Martin Fassnacht, Alexander Micko, Jürgen Honegger, Martin Reincke, Timo Deutschbein
Publikováno v:
European Journal of Endocrinology. 188:448-456
Objective Bilateral inferior petrosal sinus sampling (BIPSS) is regarded as the gold standard to differentiate between Cushing´s disease (CD) and ectopic Cushing's syndrome (ECS). However, published data on the diagnostic value of additional prolact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f81587a4876a1912dd658e44fadcf29
https://doi.org/10.1093/ejendo/lvad050
https://doi.org/10.1093/ejendo/lvad050
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 14 (2021)
Colorectal cancers (CRCs) remain one of the most common and challenging neoplasia in the Western world. The response rate of immunotherapeutic treatment approaches in a subset of advanced CRCs is remarkable and has sustainably changed treatment regim
Externí odkaz:
https://doaj.org/article/30c8f617b79743c8b71dd2e1b1ee8590
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/8c4a2e94689a4d76a16800cefe541c23