Výsledky vyhledávání - "Marco, Vacchiano"

Inhalation of peptide-loaded nanoparticles improves heart failure

Publikováno v: Science translational medicine 10 (2018). doi:10.1126/scitranslmed.aan6205
info:cnr-pdr/source/autori:Michele Miragoli, Paola Ceriotti, Michele Iafisco, Marco Vacchiano, Nicolò Salvarani, Alessio Alogna, Pierluigi Carullo, Gloria Belén Ramirez-Rodríguez, Tatiana Patrício, Lorenzo Degli Esposti, Francesca Rossi, Francesca Ravanetti, Silvana Pinelli, Rossella Alinovi, Marco Erreni, Stefano Rossi, Gianluigi Condorelli, Heiner Post, Anna Tampieri, Daniele Catalucci/titolo:Inhalation of peptide-loaded nanoparticles improves heart failure/doi:10.1126%2Fscitranslmed.aan6205/rivista:Science translational medicine/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Science Translational Medicine

Peptides are highly selective and efficacious for the treatment of cardiovascular and other diseases. However, it is currently not possible to administer peptides for cardiac-targeting therapy via a noninvasive procedure, thus representing scientific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0607564ac529f0bd0a70d2dcb1f654e

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CX3CR1-expressing inflammatory dendritic cells contribute to the progression of steatohepatitis

Autor: Cristina Bozzola, Salvatore Sutti, Aastha Jindal, S. Bruzzì, Irene Locatelli, Emanuele Albano, Marco Vacchiano

Publikováno v: Clinical Science. 129:797-808

Liver monocytes play a major role in the development of NASH (non-alcoholic steatohepatitis). In inflamed tissues, monocytes can differentiate in both macrophages and dendritic cells. In the present study, we investigated the role of moDCs (monocyte-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df99f7f3cc79313c6eb3b7ae78813ca4
https://doi.org/10.1042/cs20150053

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Bioinspired negatively charged calcium phosphate nanocarriers for cardiac delivery of MicroRNAs

Autor: Daniele Catalucci, Marco Vacchiano, Nicolò Salvarani, Pierluigi Carullo, Gloria Belén Ramírez-Rodríguez, Anna Tampieri, Tatiana Patrício, Michele Iafisco, Vittoria Di Mauro, Michele Miragoli

Publikováno v: Nanomedicine (London. Online) (2016). doi:10.2217/nnm.16.26
info:cnr-pdr/source/autori:Vittoria Di Mauro, Michele Iafisco, Nicolò Salvarani, Marco Vacchiano, Pierluigi Carullo, Gloria Belén Ramírez-Rodríguez, Tatiana Patrício, Anna Tampieri, Michele Miragoli, & Daniele Catalucci/titolo:Bio-Inspired Negatively-Charged Calcium Phosphate Nanocarriers for Cardiac Delivery of MicroRNAs/doi:10.2217%2Fnnm.16.26/rivista:Nanomedicine (London. Online)/anno:2016/pagina_da:/pagina_a:/intervallo_pagine:/volume

Aim: To develop biocompatible and bioresorbable negatively charged calcium phosphate nanoparticles (CaP-NPs) as an innovative therapeutic system for the delivery of bioactive molecules to the heart. Materials & methods: CaP-NPs were synthesized via a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e2e272ecd6ca5d0e564d06af384bb7
https://pubmed.ncbi.nlm.nih.gov/26979495

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NF-κB1 deficiency stimulates the progression of non-alcoholic steatohepatitis (NASH) in mice by promoting NKT-cell-mediated responses

Autor: Cristina Bozzola, Salvatore Sutti, Marco Vacchiano, Emanuele Albano, Irene Locatelli

Publikováno v: Clinical Science. 124:279-287

Growing evidence indicates that NF-κB (nuclear factor κB) activation contributes to the pathogenesis of NASH (non-alcoholic steatohepatisis). Among the NF-κB subunits, p50/NF-κB1 has regulatory activities down-modulating NF-κB-mediated responses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effe12f091b3a39a8ccf2e9948648ffe
https://doi.org/10.1042/cs20120289

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Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice

Autor: Irene, Locatelli, Salvatore, Sutti, Aastha, Jindal, Marco, Vacchiano, Cristina, Bozzola, Chris, Reutelingsperger, Dennis, Kusters, Stefania, Bena, Parola, Maurizio, Claudia, Paternostro, Bugianesi, Elisabetta, Simon, Mcarthur, Emanuele, Albano, Mauro, Perretti

Publikováno v: Hepatology (Baltimore, Md.)

Annexin A1 (AnxA1) is an effector of the resolution of inflammation and is highly effective in terminating acute inflammatory responses. However, its role in chronic settings is less investigated. Because changes in AnxA1 expression within adipose ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::716586ea5d409716726b322b84140028
https://pubmed.ncbi.nlm.nih.gov/24668763

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Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH

Autor: Irene Locatelli, Cristina Bozzola, Emanuele Albano, Aastha Jindal, Salvatore Sutti, Marco Vacchiano, Luca Gigliotti

Publikováno v: Hepatology (Baltimore, Md.). 59(3)

Previous studies have shown that human nonalcoholic steatohepatitis (NASH) is often associated with the presence of circulating antibodies against protein adducted by lipid peroxidation products. Here we used the methionine-choline deficient (MCD) mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0df0b739d1ba274bb54cecb64480d54
https://pubmed.ncbi.nlm.nih.gov/24115128

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