Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Marco, Rusnati"'
Autor:
Sara Taranto, Riccardo Castelli, Giuseppe Marseglia, Laura Scalvini, Federica Vacondio, Alessandra Gianoncelli, Giovanni Ribaudo, Jessica Faletti, Giorgia Gazzaroli, Edoardo Rocca, Roberto Ronca, Marco Rusnati, Antonio Sacco, Aldo Maria Roccaro, Marco Presta, Marco Mor, Arianna Giacomini, Silvia Rivara
Publikováno v:
Pharmacological Research, Vol 206, Iss , Pp 107291- (2024)
Fibroblast growth factors (FGFs) act as proangiogenic and mitogenic cytokines in several cancers, including multiple myeloma (MM). Indeed, corrupted FGF autocrine and paracrine secretion induces an aberrant activation of the FGF receptor (FGFR) signa
Externí odkaz:
https://doaj.org/article/f6f8bb6f520c433f84f652679dd1aa27
Autor:
Sergio Strizzi, Letizia Bernardo, Pasqualina D’Ursi, Chiara Urbinati, Andrea Bianco, Fiona Limanaqi, Andrea Manconi, Maria Milanesi, Alberto Macchi, Dario Di Silvestre, Adalberto Cavalleri, Giovanni Pareschi, Marco Rusnati, Mario Clerici, PierLuigi Mauri, Mara Biasin
Publikováno v:
Pharmacological Research, Vol 194, Iss , Pp 106862- (2023)
The characterization of modifications of microbial proteins is of primary importance to dissect pathogen lifecycle mechanisms and could be useful in identifying therapeutic targets. Attempts to solve this issue yielded only partial and non-exhaustive
Externí odkaz:
https://doaj.org/article/b8faaf121c8b47499bce90c1bfe39ffc
Autor:
Elena Royo-Rubio, Vanessa Martín-Cañadilla, Marco Rusnati, Maria Milanesi, Tania Lozano-Cruz, Rafael Gómez, José Luís Jiménez, Maria Ángeles Muñoz-Fernández
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 536 (2022)
Infections caused by viruses from the Herpesviridae family produce some of the most prevalent transmitted diseases in the world, constituting a serious global public health issue. Some of the virus properties such as latency and the appearance of res
Externí odkaz:
https://doaj.org/article/7bf32d3768004e50ab3d88877dad3141
Autor:
Chiara Urbinati, Maria Milanesi, Nicola Lauro, Cinzia Bertelli, Guido David, Pasqualina D’Ursi, Marco Rusnati, Paola Chiodelli
Publikováno v:
Molecules, Vol 26, Iss 24, p 7488 (2021)
HIV-1 transactivating factor Tat is released by infected cells. Extracellular Tat homodimerizes and engages several receptors, including integrins, vascular endothelial growth factor receptor 2 (VEGFR2) and heparan sulfate proteoglycan (HSPG) syndeca
Externí odkaz:
https://doaj.org/article/f2d23b145403452db13d74f779a45697
Autor:
Francesca Ferlenghi, Carmine Giorgio, Matteo Incerti, Lorenzo Guidetti, Paola Chiodelli, Marco Rusnati, Massimiliano Tognolini, Federica Vacondio, Marco Mor, Alessio Lodola
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 41 (2021)
UniPR129, an L-β-homotryptophan conjugate of the secondary bile acid lithocholic acid (LCA), acts as an effective protein-protein interaction (PPI) inhibitor of the Eph–ephrin system but suffers from a poor oral bioavailability in mice. To improve
Externí odkaz:
https://doaj.org/article/ec73d24cb22a4f48a3490411fe0f340b
Autor:
Silvia Agostini, Hashim Ali, Chiara Vardabasso, Antonio Fittipaldi, Ennio Tasciotti, Anna Cereseto, Antonella Bugatti, Marco Rusnati, Marina Lusic, Mauro Giacca
Publikováno v:
EBioMedicine, Vol 21, Iss C, Pp 170-181 (2017)
Besides its essential role in the activation of HIV-1 gene expression, the viral Tat protein has the unusual property of trafficking in and out of cells. In contrast to Tat internalization, the mechanism involved in extracellular Tat release has so f
Externí odkaz:
https://doaj.org/article/8a64912d25a74b23b44872da976b2a8e
Publikováno v:
Biomolecules, Vol 11, Iss 5, p 739 (2021)
Glycosaminoglycans (GAGs) are linear polysaccharides. In proteoglycans (PGs), they are attached to a core protein. GAGs and PGs can be found as free molecules, associated with the extracellular matrix or expressed on the cell membrane. They play a ro
Externí odkaz:
https://doaj.org/article/1d608816dea74e89934e85e90da982dc
Autor:
Angelo Musicò, Rossella Zenatelli, Miriam Romano, Andrea Zendrini, Silvia Alacqua, Selene Tassoni, Lucia Paolini, Chiara Urbinati, Marco Rusnati, Paolo Bergese, Giuseppe Pomarico, Annalisa RADEGHIERI
To be profitably exploited in medicine as drug delivery carriers, nanosized systems should be endowed with essential properties, including high biocompatibility, stealth ability to escape the immune system, prolonged circulation lifetime, and targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ccf3d00d30d90a13d37460a436f863
https://doi.org/10.26434/chemrxiv-2023-rh5s8
https://doi.org/10.26434/chemrxiv-2023-rh5s8
Publikováno v:
Molecules, Vol 20, Iss 4, Pp 6342-6388 (2015)
Angiogenesis, the process of formation of new blood vessel from pre-existing ones, is involved in various intertwined pathological processes including virus infection, inflammation and oncogenesis, making it a promising target for the development of
Externí odkaz:
https://doaj.org/article/dee0bc0f645746d38a2670e6d7daf5c9
Autor:
Paola Fossa, Matteo Uggeri, Alessandro Orro, Chiara Urbinati, Alessandro Rondina, Maria Milanesi, Nicoletta Pedemonte, Emanuela Pesce, Rita Padoan, Robert C. Ford, Xin Meng, Marco Rusnati, Pasqualina D’Ursi
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12274
Cystic fibrosis is a hereditary disease mainly caused by the deletion of the Phe 508 (F508del) of the cystic fibrosis transmembrane conductance regulator (CFTR) protein that is thus withheld in the endoplasmic reticulum and rapidly degraded by the ub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4dc9b7e78fd967f8fa5075aeb80c4d
https://pubmed.ncbi.nlm.nih.gov/36293130
https://pubmed.ncbi.nlm.nih.gov/36293130