Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Marco, Pravetoni"'
Autor:
Justas Rodarte, Carly Baehr, Dustin Hicks, Morgan McGovern, Yue Zhang, Pedro Silva-Ortiz, Bryan Hannon, Sowmya Duddu, Marie Pancera, Marco Pravetoni
Publikováno v:
ACS Omega, Vol 9, Iss 41, Pp 42506-42519 (2024)
Externí odkaz:
https://doaj.org/article/d5f231fee7e14678afaec8db267de2b8
Autor:
Tyler B Rollman, Zachary W Berkebile, Dustin M Hicks, Jason S Hatfield, Priyanka Chauhan, Marco Pravetoni, Mark R Schleiss, Gregg N Milligan, Terry K Morgan, Craig J Bierle
Publikováno v:
PLoS Pathogens, Vol 20, Iss 11, p e1012515 (2024)
Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus and the leading cause of infectious disease related birth defects worldwide. How the immune response modulates the risk of intrauterine transmission of HCMV after maternal infection remains poo
Externí odkaz:
https://doaj.org/article/df1cfc2017244bd68b3986eb4767e126
Autor:
Saadyah E. Averick, Andrew J. Kassick, Daihyun Song, Borui Zhang, Jennifer Vigliaturo, Diego Luengas, Pedro Silva-Ortiz, Marco Pravetoni, Michael D. Raleigh
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionFentanyl and fentanyl analogs (F/FA) have become increasingly common adulterants in counterfeit prescription pills and illicit street drug mixtures due to their ease of synthesis and exceedingly high potency. The ongoing epidemic of fatal
Externí odkaz:
https://doaj.org/article/86ed8107bf8a4408b5e7152bbfc265b8
Autor:
Bethany Crouse, Shannon M. Miller, Peter Muelken, Linda Hicks, Jennifer R. Vigliaturo, Cheryl L. Marker, Alonso G. P. Guedes, Paul R. Pentel, Jay T. Evans, Mark G. LeSage, Marco Pravetoni
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Opioid use disorders (OUD) and overdose are public health threats worldwide. Widespread access to highly potent illicit synthetic opioids such as fentanyl is driving the recent rise in fatal overdoses. Vaccines containing fentanyl-based hapt
Externí odkaz:
https://doaj.org/article/84711b1689474c11879e5e0dec9e620c
Autor:
Shannon M. Miller, Bethany Crouse, Linda Hicks, Hardik Amin, Shelby Cole, Helene G. Bazin, David J. Burkhart, Marco Pravetoni, Jay T. Evans
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Opioid use disorders (OUD) and opioid-related fatal overdoses are a public health concern in the United States. Approximately 100,000 fatal opioid-related overdoses occurred annually from mid-2020 to the present, the majority of which involv
Externí odkaz:
https://doaj.org/article/1da1be1405e24b4a9876d785eb6244f4
Autor:
Gianna Triller, Evi P. Vlachou, Hamidreza Hashemi, Monique van Straaten, Johan P. Zeelen, Yosip Kelemen, Carly Baehr, Cheryl L. Marker, Sandra Ruf, Anna Svirina, Monica Chandra, Katharina Urban, Anastasia Gkeka, Sebastian Kruse, Andreas Baumann, Aubry K. Miller, Marc Bartel, Marco Pravetoni, C. Erec Stebbins, F. Nina Papavasiliou, Joseph P. Verdi
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112049- (2023)
Summary: Poorly immunogenic small molecules pose challenges for the production of clinically efficacious vaccines and antibodies. To address this, we generate an immunization platform derived from the immunogenic surface coat of the African trypanoso
Externí odkaz:
https://doaj.org/article/c7ecefeb83cd43648db62b9d9e7b1931
Autor:
Bethany Crouse, Li Zhang, Christine Robinson, Yuguang Ban, Jennifer R Vigliaturo, Sabita Roy, Marco Pravetoni
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 11, Pp 4383-4392 (2021)
Vaccines offer a promising prophylactic and therapeutic intervention to counteract opioid use disorders (OUD) and fatal overdoses. Vaccines generate opioid-specific antibodies that bind the target opioid, reducing drug distribution to the brain and p
Externí odkaz:
https://doaj.org/article/273d73dc5eff46a8bc6848d8f04bc795
Autor:
Dustin Hicks, Carly Baehr, Pedro Silva-Ortiz, Aaron Khaimraj, Diego Luengas, Fatima A. Hamid, Marco Pravetoni
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 6 (2022)
Innovative therapies to complement current treatments are needed to curb the growing incidence of fatal overdoses related to synthetic opioids. Murine and chimeric monoclonal antibodies (mAb) specific for fentanyl and its analogs have demonstrated pr
Externí odkaz:
https://doaj.org/article/d5eb2b213dc94e53bb6b3a3efe917e33
Autor:
Addison E. Stone, Sarah E. Scheuermann, Colin N. Haile, Gregory D. Cuny, Marcela Lopez Velasquez, Joshua P. Linhuber, Anantha L. Duddupudi, Jennifer R. Vigliaturo, Marco Pravetoni, Therese A. Kosten, Thomas R. Kosten, Elizabeth B. Norton
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Fentanyl is a major contributor to the devastating increase in overdose deaths from substance use disorders (SUD). A vaccine targeting fentanyl could be a powerful immunotherapeutic. Here, we evaluated adjuvant and delivery strategies for co
Externí odkaz:
https://doaj.org/article/644008cc7a484a358b436c0687cf30dc
Autor:
Christine Robinson, Carly Baehr, Shirdi E. Schmiel, Claudia Accetturo, Daniel L. Mueller, Marco Pravetoni
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 4, Pp 909-917 (2019)
Opioid use disorders (OUD) and fatal overdoses are a national emergency in the United States. Therapeutic vaccines offer a promising strategy to treat OUD and reduce the incidence of overdose. Immunization with opioid-based haptens conjugated to immu
Externí odkaz:
https://doaj.org/article/1b30b28fd85c4879a92a06ee87143378