Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marco, Craveiro"'
Autor:
François Van Laethem, Abhisek Bhattacharya, Marco Craveiro, Jinghua Lu, Peter D. Sun, Alfred Singer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Understanding the generation of an MHC-restricted T cell repertoire is the cornerstone of modern T cell immunology. The unique ability of αβT cells to only recognize peptide antigens presented by MHC molecules but not conformational antigens is ref
Externí odkaz:
https://doaj.org/article/76e87e0eec1242be99fc58fb598e83f1
Autor:
Jinghua Lu, François Van Laethem, Abhisek Bhattacharya, Marco Craveiro, Ingrid Saba, Jonathan Chu, Nicholas C. Love, Anastasia Tikhonova, Sergei Radaev, Xiaoping Sun, Annette Ko, Tomer Arnon, Eric Shifrut, Nir Friedman, Nan-Ping Weng, Alfred Singer, Peter D. Sun
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
For T cells, functional antigen receptors are selected in the thymus from a pre-selection repertoire by interaction with self MHCs. Here the authors show that specific, non-germline coded features located in the complementarity determining region 3 o
Externí odkaz:
https://doaj.org/article/2135b8948a994dbda344f75d21b684fb
Autor:
Xuguang Tai, Alyssa Indart, Mirelle Rojano, Jie Guo, Nicolai Apenes, Tejas Kadakia, Marco Craveiro, Amala Alag, Ruth Etzensperger, Mohamed Elsherif Badr, Flora Zhang, Zhongmei Zhang, Jie Mu, Terry Guinter, Assiatu Crossman, Larry Granger, Susan Sharrow, Xuyu Zhou, Alfred Singer
Publikováno v:
Nature Immunology. 24:637-651
Thymocytes bearing autoreactive T cell receptors (TCRs) are agonist-signaled by TCR/co-stimulatory molecules to either undergo clonal deletion or to differentiate into specialized regulatory T (Treg) or effector T (Teff) CD4+ cells. How these differe
Autor:
Alice Machado, Marie Pouzolles, Sarah Gailhac, Vanessa Fritz, Marco Craveiro, Uriel López-Sánchez, Taisuke Kondo, Francesca Pala, Marita Bosticardo, Luigi D. Notarangelo, Vincent Petit, Naomi Taylor, Valérie S. Zimmermann
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Thymocyte differentiation is dependent on the availability and transport of metabolites in the thymus niche. As expression of metabolite transporters is a rate-limiting step in nutrient utilization, cell surface transporter levels generally reflect t
Externí odkaz:
https://doaj.org/article/ca18d4a5e29d4484a335f110d8e2fd0c
Autor:
Cem Sievers, Marco Craveiro, Jay Friedman, Yvette Robbins, Xinping Yang, Ke Bai, Andy Nguyen, Jason M. Redman, Raj Chari, Patrick Soon-Shiong, Jeffrey Schlom, James Gulley, Clint T. Allen
Publikováno v:
Cancer Cell. 41:887-902.e5
Publikováno v:
Cancer Research. 83:6422-6422
Head and neck squamous cell carcinoma (HNSCC) unrelated to human papillomavirus (HPV) confers poor prognosis, with half of patients experiencing disease relapse in advanced stages. Response rates to traditional immunotherapies are low and novel appro
Autor:
Marco Craveiro
MDE (Model Driven Engineering) is an approach to software engineering centred around modeling. Code generators are an important component of the MDE toolset because they bridge the gap between models and their implementation. Studies have demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369bf7e5a9adb52bc72b5a1059403ce9
Autor:
Marco Craveiro
This paper is an experience report that analyses the use of MDDtechniques to create and maintain a new software system for a large financial company. At the time of writing, the system has been in production for over nine years, providing a platform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684bba93a2737cb706cb372b158076aa
Autor:
Taisuke Kondo, Francesca Pala, Sarah Gailhac, Naomi Taylor, Vanessa Fritz, Alice Machado, Uriel López-Sánchez, Vincent Petit, Luigi D. Notarangelo, Marita Bosticardo, Valérie S. Zimmermann, Marco Craveiro, Marie Pouzolles
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2020, ⟨10.3389/fimmu.2020.01562⟩
Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2020, ⟨10.3389/fimmu.2020.01562⟩
Thymocyte differentiation is dependent on the availability and transport of metabolites in the thymus niche. As expression of metabolite transporters is a rate-limiting step in nutrient utilization, cell surface transporter levels generally reflect t