Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Marco, Bortoli"'
Autor:
Luca Sancineto, Francesca Mangiavacchi, Agnieszka Dabrowska, Agata J. Pacuła-Miszewska, Magdalena Obieziurska-Fabisiak, Cecilia Scimmi, Veronica Ceccucci, Juan Kong, Yao Zhao, Gianluca Ciancaleoni, Vanessa Nascimento, Bruno Rizzuti, Marco Bortoli, Laura Orian, Anna Kula-Pacurar, Haitao Yang, Jacek Ścianowski, Ying Lei, Krzysztof Pyrc, Claudio Santi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Although global vaccination campaigns alleviated the SARS-CoV-2 pandemic in terms of morbidity and mortality, the ability of the virus to originate mutants may reduce the efficacy of vaccines, posing a serious risk of a renewed pandemic. The
Externí odkaz:
https://doaj.org/article/226d7ea937b54aa098a61f09b34778cd
Autor:
Giovanni Ribaudo, Davide Zeppilli, Alberto Ongaro, Marco Bortoli, Giuseppe Zagotto, Laura Orian
Publikováno v:
Chemistry, Vol 5, Iss 3, Pp 1488-1496 (2023)
Due to its endogenously high oxygen consumption, the central nervous system (CNS) is vulnerable to oxidative stress conditions. Notably, the activity of several CNS-targeting compounds, such as antidepressant and hypnotic drugs, or endogenous mediato
Externí odkaz:
https://doaj.org/article/5d40696b3d9940f8beb41a2c1ac5989c
Autor:
Giovanni Ribaudo, Marco Bortoli, Colby E. Witt, Brenna Parke, Sergio Mena, Erika Oselladore, Giuseppe Zagotto, Parastoo Hashemi, Laura Orian
Publikováno v:
ACS Omega, Vol 7, Iss 10, Pp 8314-8322 (2022)
Externí odkaz:
https://doaj.org/article/9a46637c867c44b498b643e54f45aaaf
Autor:
Davide Zeppilli, Anna Aldinio-Colbachini, Giovanni Ribaudo, Cristina Tubaro, Marco Dalla Tiezza, Marco Bortoli, Giuseppe Zagotto, Laura Orian
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11797 (2023)
We set up an in silico experiment and designed a chimeric compound integrating molecular features from different efficient ROS (Reactive Oxygen Species) scavengers, with the purpose of investigating potential relationships between molecular structure
Externí odkaz:
https://doaj.org/article/0467adda07224390955d1e503110e662
Autor:
Davide Zeppilli, Giovanni Ribaudo, Nicola Pompermaier, Andrea Madabeni, Marco Bortoli, Laura Orian
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 525 (2023)
The reactive oxygen species (ROS) scavenging capacities of ginkgolides and bilobalide, which are the peculiar constituents of the extract of Ginkgo biloba, are investigated in silico (level of theory: (SMD)-M06-2X/6-311+G(d,p)//M06-2X/6-31G(d)). Unli
Externí odkaz:
https://doaj.org/article/8ba06ba21d7c46008260269bbb8381aa
Autor:
Marco Bortoli, Marco Dalla Tiezza, Cecilia Muraro, Chiara Pavan, Giovanni Ribaudo, Anna Rodighiero, Cristina Tubaro, Giuseppe Zagotto, Laura Orian
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 311-318 (2019)
Zolpidem (N,N-Dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide) is a well-known drug for the treatment of sleeping disorders. Recent literature reports on positive effects of zolpidem therapy on improving renal damage after
Externí odkaz:
https://doaj.org/article/1e79f86ffd194e5f8b6f23af684fd6a3
Autor:
Folorunsho Bright Omage, Andrea Madabeni, Amanda Resende Tucci, Pablo Andrei Nogara, Marco Bortoli, Alice dos Santos Rosa, Vivian Neuza dos Santos Ferreira, João Batista Teixeira Rocha, Milene Dias Miranda, Laura Orian
Publikováno v:
Journal of Chemical Information and Modeling. 63:2226-2239
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fed44f9838b9204114d1ff5874c0c8e
https://doi.org/10.1021/acs.jcim.3c00168
https://doi.org/10.1021/acs.jcim.3c00168
Autor:
Pablo A. Nogara, Cláudia S. Oliveira, Andrea Madabeni, Marco Bortoli, João Batista T. Rocha, Laura Orian
Publikováno v:
New Journal of Chemistry. 47:5796-5803
A combination of spectroscopic, chromatographic and computational approaches was employed to investigate the reaction of several diselenides with a thiolate nucleophile, leading to the breaking of the selenium–selenium (Se–Se) bond.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b217126a8bda808985f61409e0ccda43
https://doi.org/10.1039/d2nj05976b
https://doi.org/10.1039/d2nj05976b
Autor:
Giuseppe Zagotto, Marco Bortoli
Publikováno v:
Molecules, Vol 26, Iss 22, p 7061 (2021)
Medicinal chemistry is facing new challenges in approaching precision medicine. Several powerful new tools or improvements of already used tools are now available to medicinal chemists to help in the process of drug discovery, from a hit molecule to
Externí odkaz:
https://doaj.org/article/f8ec789563cf48f1a37e870e8109bc0e
Autor:
Xueqing Wang, Lilia Kinziabulatova, Marco Bortoli, Anju Manickoth, Marisa A. Barilla, Haiyan Huang, Lluís Blancafort, Bern Kohler, Jean-Philip Lumb
Publikováno v:
Nature Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d34a4d1266af27a1f89bace36be503f
https://doi.org/10.1038/s41557-023-01175-4
https://doi.org/10.1038/s41557-023-01175-4